Results 41 to 50 of about 10,062 (208)

PRMT1 driven PTX3 regulates ferritinophagy in glioma

Autophagy, 2023
Mutations in the Krebs cycle enzyme IDH1 (isocitrate dehydrogenase (NADP(+)) 1) are associated with better prognosis in gliomas. Though IDH1 mutant (IDH1R132H) tumors are characterized by their antiproliferative signatures maintained through hypermethylation of DNA and chromatin, mechanisms affecting cell death pathways in these tumors are not well ...
Kirti Lathoria, Pruthvi Gowda, Sonia B Umdor, Shruti Patrick, Vaishali Suri, Ellora Sen   +5 more
openaire   +2 more sources

Long pentraxin PTX3 exacerbates pressure overload-induced left ventricular dysfunction.

PLoS ONE, 2013
BackgroundLeft ventricular hypertrophy is enhanced by an inflammatory state and stimulation of various cytokines. Pentraxin 3 (PTX3) is rapidly produced in response to inflammatory signals, and high plasma PTX3 levels are seen in patients with heart ...
Satoshi Suzuki, Tetsuro Shishido, Akira Funayama, Shunsuke Netsu, Mitsunori Ishino, Tatsuro Kitahara, Toshiki Sasaki, Shigehiko Katoh, Yoichiro Otaki, Tetsu Watanabe, Yoko Shibata, Alberto Mantovani, Yasuchika Takeishi, Isao Kubota   +13 more
doaj   +1 more source

Plasma Pentraxin-3 Combined with Plaque Characteristics Predict Cardiovascular Risk in ST-Segment Elevated Myocardial Infarction: An Optical Coherence Tomography Study

Journal of Inflammation Research, 2021
Ying Wang,1 Xiaoxiao Zhao,1 Peng Zhou,1 Chen Liu,1 Zhaoxue Sheng,1,2 Jiannan Li,1 Jinying Zhou,1 Runzhen Chen,1 Yi Chen,1 Li Song,1 Hanjun Zhao1 *, Hongbing Yan3 𪇞partment of Cardiology, Fuwai Hospital, National Center for Cardiovascular ...
Wang Y, Zhao X, Zhou P, Liu C, Sheng Z, Li J, Zhou J, Chen R, Chen Y, Song L, Zhao H, Yan H   +11 more
doaj  

Role of complement and Fc{gamma} receptors in the protective activity of the long pentraxin PTX3 against Aspergillus fumigatus

, 2010
Pentraxin 3 (PTX3) is a soluble pattern recognition molecule playing a nonredundant role in resistance against Aspergillus fumigatus. The present study was designed to investigate the molecular pathways involved in the opsonic activity of PTX3.
F. Moalli, Luigina Romani, Livija Deban, Moalli, Federica, Romani, Luigina, Doni, Andrea, A. Doni, Federica Moalli, Andrea Doni, L. Deban, B. Bottazzi, Teresa Zelante, Cecilia Garlanda, Deban, Livija, C. Garlanda, L. Romani, Zagarella, Silvia, Barbara Bottazzi, Bottazzi, Barbara, Mantovani, Alberto, Alberto Mantovani, T. Zelante, A. Mantovani, Silvia Zagarella, S. Zagarella, Zelante, Teresa, Garlanda, Cecilia   +26 more
core   +2 more sources

Prognostic Value of Plasma Pentraxin-3 Levels in Patients with Stable Coronary Artery Disease after Drug-Eluting Stent Implantation

Mediators of Inflammation, 2014
Pentraxin-3 (PTX3) is an inflammatory marker thought to be more specific to cardiovascular inflammation than C-reactive protein (CRP). Our aim was to assess the prognostic value of PTX3 in patients with stable coronary artery disease (CAD) after drug ...
Liu Haibo, Guo Xiaofang, Wang Chunming, Yuan Jie, Chen Guozhong, Zhang Limei, Cao Yong, Fang Yu, Bao Yingchun, Yu Wangjun, Ge Junbo   +10 more
doaj   +1 more source

Circulating Pentraxin3-Specific B Cells Are Decreased in Lupus Nephritis

Frontiers in Immunology, 2019
Background: Pentraxin3 (PTX3) is overexpressed in kidneys of patients developing lupus nephritis (LN). Active LN is associated with reduced anti-PTX3 antibodies. However, abnormalities of B cell differentiation against PTX3 have not been characterized in
Mariele Gatto, Mariele Gatto, Annika Wiedemann, Nadja Nomovi, Karin Reiter, Eva Schrezenmeier, Thomas Rose, Franziska Szelinski, Andreia C. Lino, Sonia Valentino, Anna Ghirardello, Thomas Dörner, Andrea Doria   +12 more
doaj   +1 more source

Host-protective effect of circulating pentraxin 3 (PTX3) and complex formation with neutrophil extracellular traps

Frontiers in Immunology, 2012
Pentraxin 3 (PTX3) is a soluble pattern recognition receptor which is classified as a long-pentraxin in the pentraxin family. It is known to play an important role in innate immunity, inflammatory regulation and female fertility.
Kenji eDaigo, Takao eHamakubo
doaj   +1 more source

PTX3 promotes fibrocyte differentiation.

, 2015
Human PBMC were incubated for 5 days in the absence A) or presence B) of 1 μg/ml PTX3. Bar is 50 μm. C) The effect of the indicated concentrations of PTX3 on fibrocyte numbers. For each donor, numbers were normalized to the no-PTX3 control.
Richard H. Gomer (214653), J. Sjef Verbeek (237095), Darrell Pilling (68014), Nehemiah Cox (307503), Varsha Vakil (65341)   +4 more
core   +1 more source

Anti-pentraxin 3 auto-antibodies might be protective in lupus nephritis: a large cohort study

Renal Failure, 2017
Objectives: Anti-pentraxin 3 (PTX3) auto-antibodies were found to be associated with the absence of renal involvement in systemic lupus erythematosus (SLE).
Mo Yuan, Ying Tan, Yun Pang, Yong-zhe Li, Yan Song, Feng Yu, Ming-hui Zhao   +6 more
doaj   +1 more source

Predictors of PTX3.

, 2017
Predictors of PTX3.
Gia Deyab (3772243), Stefan Agewall (3772246), Pier Luigi Meroni (630402), Jon Elling Whist (703534), Milada Cvancarova Småstuen (670566), Ivana Hollan (569836), Roberto Leone (351422), Gunnbjorg Hjeltnes (3772249), Torstein Lyberg (193898), Ingrid Hokstad (3772240), Barbara Bottazzi (291673)   +10 more
core   +1 more source