Results 91 to 100 of about 100,999 (254)

Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche. [PDF]

open access: yes, 2014
Age at menarche is a marker of timing of puberty in females. It varies widely between individuals, is a heritable trait and is associated with risks for obesity, type 2 diabetes, cardiovascular disease, breast cancer and all-cause mortality.
A Kong   +271 more
core   +7 more sources

Distinct gray matter and metabolic characteristics in hypothalamic hamartoma network with different semiology

open access: yesEpilepsia, EarlyView.
Abstract Objective Hypothalamic hamartomas (HHs) are developmental malformations associated with focal epilepsy. We investigated the patterns of gray matter morphology and cerebral metabolism in individuals with HHs, with and without focal to bilateral tonic–clonic seizures (FBTCSs), aiming to clarify the accompanying network abnormalities.
Yihe Wang   +12 more
wiley   +1 more source

A Testicular Leydig Cell Tumor; An Uncommon Cause of Precocious Puberty: A Case Report With Secondary Central Precocious Puberty

open access: yesActa Medica Iranica, 2023
Sexual precocity in boys is defined as any sign of secondary sexual characteristics present before the age of 9. Leydig cell tumors of the testes are a rare cause of peripheral precocious puberty in boys.
Seyede Tahereh Mousavi   +2 more
doaj  

The Association of Gut Microbiota With Idiopathic Central Precocious Puberty in Girls

open access: yesFrontiers in Endocrinology, 2020
Idiopathic central precocious puberty (ICPP) is a relatively common condition in preadolescent girls, and its pathogenesis remains to be uncovered. A variety of studies have highlighted the association of gut microbiota (GM) with endocrine diseases, such
G. Dong   +15 more
semanticscholar   +1 more source

Central Precocious Puberty Alters the Mammary Gland Epithelial Landscape in Female Rats [PDF]

open access: yes, 2017
Precocious puberty (PP) is a serious endocrine disorder associated with an increased risk for development of breast cancer (BC) later in life. However, the lack of a strong in vivo model has made it difficult to study this relationship.
Hamilton, Alina M.
core   +1 more source

Persistence of EEG abnormalities in KCNT1‐related DEE in an adult patient

open access: yes
Epileptic Disorders, EarlyView.
Haania Kakwan   +3 more
wiley   +1 more source

Body size of male Atlantic salmon (Salmo salar L.) at introduction of a 5‐week LD12:12 winter signal influences their decision to mature early or smoltify

open access: yesJournal of Fish Biology, EarlyView.
Abstract Sexual maturation of male Atlantic salmon post‐smolts (‘jacking’) is undesired in aquaculture and seems to occur due to the intensification in modern facilities. Maturation depends on internal and external factors (temperature, photoperiod, feed availability, energy levels, body size, genetic background) that act on the brain‐pituitary‐gonad ...
Enrique Pino‐Martinez   +5 more
wiley   +1 more source

Prenatal exposure to mercury and precocious puberty: a prospective birth cohort study.

open access: yesHuman Reproduction, 2020
STUDY QUESTION Is in utero exposure to mercury associated with the risk of precocious puberty? SUMMARY ANSWER Prenatal exposure to high levels of mercury was associated with increased risk of precocious puberty, which was strengthened by concomitant ...
Guoying Wang   +3 more
semanticscholar   +1 more source

Long-Term Follow-Up Results of Gamma Knife Radiosurgery for Hypothalamic Hamartoma : How can we Improve the Results? [PDF]

open access: yes, 2005
Objective: Hypothalamic hamartomas (HH) constitute rare developmental lesions associated with gelastic seizure, precocious puberty, and abnormal behavior. Treatment for this lesion is very complicated due to its location.
김동석   +6 more
core  

Reproductive and developmental effects of phthalate diesters in females. [PDF]

open access: yes, 2013
Phthalate diesters, widely used in flexible plastics and consumer products, have become prevalent contaminants in the environment. Human exposure is ubiquitous and higher phthalate metabolite concentrations documented in patients using medications with ...
Chambers, Christina   +2 more
core   +1 more source

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