Results 51 to 60 of about 105,353 (261)

A review of the genetics and epigenetics of central precocious puberty

open access: yesFrontiers in Endocrinology, 2022
Gonadotrophin dependent sexual precocity, commonly referred to as central precocious puberty (CPP), results from a premature reactivation of the hypothalamic-pituitary-gonadal (HPG) axis before the normal age of pubertal onset.
J. Moise-Silverman, L. Silverman
semanticscholar   +1 more source

On the origin of trisomy 21 Down syndrome [PDF]

open access: yes, 2008
Background: Down syndrome, characterized by an extra chromosome 21 is the most common genetic cause for congenital malformations and learning disability.
Hultén, Maj A.   +6 more
core   +2 more sources

A preliminary study on the relationship between environmental endocrine disruptors and precocious puberty in girls

open access: yesJournal of Pediatric Endocrinology & Metabolism (JPEM), 2022
Objectives To explore the associations of environmental endocrine disruptors on precocious puberty in girls. Methods This was a case-control study in which 30 girls with precocious puberty and 46 age- and race-matched prepubertal females were enrolled ...
Fang Zhou   +5 more
semanticscholar   +1 more source

The critical BMI hypothesis for puberty initiation and the gender prevalence difference: Evidence from an epidemiological survey in Beijing, China

open access: yesFrontiers in Endocrinology, 2022
BackgroundAlthough previous studies suggested that there is a certain level of body fat mass before puberty can be initiated, most studies have focused on girls.ObjectiveTo investigate the relationship between precocious puberty and physical growth in ...
Meijuan Liu   +10 more
doaj   +1 more source

Genetic, epigenetic and enviromental influencing factors on the regulation of precocious and delayed puberty

open access: yesFrontiers in Endocrinology, 2022
The pubertal development onset is controlled by a network of genes that regulate the gonadotropin releasing hormone (GnRH) pulsatile release and the subsequent increase of the circulating levels of pituitary gonadotropins that activate the gonadal ...
M. Faienza   +5 more
semanticscholar   +1 more source

The effect of environmental factors on precocious puberty in children: a case–control study

open access: yesBMC Pediatrics, 2023
Background Recently the prevalence of precocious puberty development is increasing among Chinese children. Proper understanding of the risk factors for precocious puberty in children is pivotal as could help to improve children's health.
Francis Manyori Bigambo   +6 more
doaj   +1 more source

Identification and Characterization of lncRNA and mRNA in Testes of Landrace and Hezuo Boars

open access: yesAnimals, 2021
Chinese HZ boars are typical plateau miniature boars characterized by precocious puberty, which is closely related to testicular development and spermatogenesis.
Bo Zhang   +9 more
doaj   +1 more source

Atualização em etiologia, diagnóstico e manejo da precocidade sexual [PDF]

open access: yes, 2008
Precocious puberty is defined as the development of secondary sexual characteristics before the age of 8 years in girls and 9 years in boys. Gonadotropin-dependent precocious puberty (GDPP) results from the premature activation of the hypothalamic ...
ARNHOLD, Ivo J. P.   +3 more
core   +2 more sources

Central precocious puberty: Recent advances in understanding the aetiology and in the clinical approach

open access: yesClinical Endocrinology, 2021
Central precocious puberty (CPP) results from early activation of the hypothalamic‐pituitary‐gonadal (HPG) axis. The current state of knowledge of the complex neural network acting at the level of the hypothalamus and the GnRH neuron to control puberty ...
L. Maione, C. Bouvattier, U. Kaiser
semanticscholar   +1 more source

Central precocious puberty in a girl with LEGIUS syndrome: an accidental association?

open access: yesItalian Journal of Pediatrics, 2021
Background Central precocious puberty is a condition characterized by precocious activation of the hypothalamic-pituitary-gonadal axis. It may be idiopathic or secondary to organic causes, including syndromes such as Neurofibromatosis type 1 (NF1).
Valentina Orlandi   +4 more
doaj   +1 more source

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