Results 81 to 90 of about 100,999 (254)

Weight Gain in Infancy and Childhood Were Associated With Pubertal Development in Boys and Girls

Acta Paediatrica, EarlyView.
ABSTRACT Aim As earlier puberty has been associated with higher later metabolic risk, we studied how weight gain in infancy and childhood is associated with pubertal timing and duration in healthy children. Method Leveraging the longitudinal data from the Special Turku Coronary Risk Factor Intervention Project study, we used linear regression analyses ...
Saga Rebecca Nummela, Katja Pahkala, Sinikka Karppinen, Jorma Toppari, Olli Raitakari, Harri Niinikoski   +5 more
wiley   +1 more source

Ovarian cysts and tumors as the cause of isosexual pseudoprecocious puberty [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2006
Introduction. Precocious puberty in girls is generally defined as appearance of secondary sexual characteristics before eight years of age. Menarche before the ninth birthday may serve as an additional criterion.
Mitrović Katarina, Zdravković Dragan, Milenković Tatjana, Sedlecki Katarina, Stanković Zoran   +4 more
doaj   +1 more source

Trends in the Incidence of Central Precocious Puberty and Normal Variant Puberty Among Children in Denmark, 1998 to 2017

JAMA Network Open, 2020
Key Points Question Have the annual incidence rates of central precocious puberty (CPP) and normal variant puberty (ie, premature thelarche and premature adrenarche) increased during the past 20 years in Denmark?
E. V. Bräuner, A. Busch, Camilla Eckert-Lind, T. Koch, M. Hickey, A. Juul   +5 more
semanticscholar   +1 more source

Moderate Day‐To‐Day Variation in First‐Morning Urine Total Luteinizing Hormone Levels Supports the Use of a Single Determination to Identify Imminent Puberty

Clinical Endocrinology, Volume 102, Issue 5, Page 578-588, May 2025.
ABSTRACT Objectives We aimed to study the daily variation in first‐morning urinary total luteinizing hormone (U‐LH) determination and validate it as a noninvasive method for analyzing age‐ and pubertal stage‐related changes in LH immunoreactivity (LH‐ir) levels to predict imminent onset of central puberty.
And Demir, Matti Hero, Anders Juul, Katharina M. Main   +3 more
wiley   +1 more source

Society for Endocrinology Clinical Practice Guideline for the Evaluation of Androgen Excess in Women

Clinical Endocrinology, EarlyView.
ABSTRACT Context Androgen excess is common in women and refers to clinical or biochemical evidence of elevated androgenic steroids such as testosterone. It is associated with underlying polycystic ovary syndrome in the majority of cases. However severe androgen excess is less common and may indicate the presence of underlying adrenal or ovarian ...
Yasir S. Elhassan, James M. Hawley, Leanne Cussen, Ali Abbara, Sophie A. Clarke, Punith Kempegowda, Rima K. Dhillon‐Smith, Puja Thadani, Maureen Busby, Lucy Owusu‐Darkwah, Rachel Marrington, W. Colin Duncan, Robert K. Semple, Richard Quinton, Michael W. O'Reilly   +14 more
wiley   +1 more source

GENETICS IN ENDOCRINOLOGY: Genetic etiologies of central precocious puberty and the role of imprinted genes.

European Journal of Endocrinology, 2020
Pubertal timing is regulated by the complex interplay of genetic, environmental, nutritional and epigenetic factors. Criteria for determining normal pubertal timing, and thus the definition of precocious puberty, have evolved based on published ...
S. Roberts, U. Kaiser
semanticscholar   +1 more source

Identification and Optimization of Contributing Factors for Precocious Puberty by Machine/Deep Learning Methods in Chinese Girls

Frontiers in Endocrinology, 2022
Background and ObjectivesAs the worldwide secular trends are toward earlier puberty, identification of contributing factors for precocious puberty is critical.
Bo Pang, Bo Pang, Qiong Wang, Qiong Wang, Min Yang, Min Yang, Mei Xue, Mei Xue, Yicheng Zhang, Yicheng Zhang, Xiangling Deng, Xiangling Deng, Zhixin Zhang, Zhixin Zhang, Wenquan Niu   +14 more
doaj   +1 more source

Pathogenic variants in chromatin‐related genes: Linking immune dysregulation to neuroregression and acute neuropsychiatric disorders

Developmental Medicine &Child Neurology, EarlyView.
Chromatin machinery influences how DNA is ‘wrapped’ around histones in the nucleosome of immune and brain cells. Plain language summary: https://onlinelibrary.wiley.com/doi/10.1111/dmcn.16299 Abstract We report eight children with de novo pathogenic DNA variants in chromatin‐related genes: MORC2, CHD7, KANSL1, KMT2D, ZMYND11, HIST1HIE, EP300, and KMT2B.
Russell C. Dale, Shekeeb Mohammad, Velda X. Han, Hiroya Nishida, Himanshu Goel, Stuart G. Tangye, Georgina Hollway, Esther Tantsis, Deepak Gill, Shrujna Patel, Chromatin Immune‐Brain Group, Michael Lonergan, Melanie Wong, Kavitha Kothur, Erica Tsang   +14 more
wiley   +1 more source

Central precocious puberty

Definitions, 2020
Central precocious puberty is a condition that causes early sexual development in girls and boys. While puberty normally starts between ages 8 and 13 in girls and between ages 9 and 14 in boys, girls with central precocious puberty begin exhibiting signs

semanticscholar   +1 more source

Developmental and epileptic encephalopathy in patients with epilepsy due to hypothalamic hamartomas

Epilepsia, EarlyView.
Abstract Objective What factors influence cognition and behavior in patients with epilepsy caused by hypothalamic hamartoma (HH)? Methods We conducted a retrospective study of 103 patients referred to the Epilepsy Center in Freiburg, Germany, over the past 24 years.
Kathrin Wagner, Theo Demerath, Sarah Metzger, Friederike Niedermoser, Birgitta Metternich, Lisa Putzar, Horst Urbach, Victoria San Antonio‐Arce, Kerstin Alexandra Klotz, Andreas Schulze‐Bonhage   +9 more
wiley   +1 more source