Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Measuring, Predicting and Controlling Disruption Impacts for Urban Public Transport
, 2020 Menno Yap
openalex +2 more sources
IMPROVING THE QUALITY OF PASSENGER SERVICE IN CITY PUBLIC TRANSPORT
, 2022 Suyunov Oltibek Do'stmurodovich Kuziyev Abdimurot Uroqovich
openalex +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Bicycle transport as an object of ecological marketing and innovations in urban transportations [PDF]
Marketing i Menedžment Innovacij, 2016 The aim of the article. In the modern world society is faced with problems of growing population, increasing environmental problems, lack of minerals and social-economic globalization when necessity of both individual and humanity survival is becoming ...
O.S. Teletov +2 more
doaj
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Impact of Car-Sharing and Ridesourcing on Public Transport Use: Attitudes, Preferences, and Future Intentions Regarding Sustainable Urban Mobility in the Post-Soviet City [PDF]
, 2022 Rozaliia Tarnovetckaia, Hamid Mostofi
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Homologous expression and purification of human HAX‐1 for structural studies
FEBS Open Bio, EarlyView.This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley +1 more source
Smart Mobile Application for Public Transport Schedules - Logical Model [PDF]
, 2020 Georgi Krastev, Valentina Voinohovska
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Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source