Results 141 to 150 of about 80,002 (308)

Metabolic Dysfunction‐Associated Steatotic Liver Disease and Obesity: Pathogenesis, Diagnostics, Risk Stratification, and Therapeutic Approach

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) has emerged as the most prevalent chronic liver disease worldwide, closely linked to the global rising incidence of obesity and metabolic syndrome. This review synthesizes current evidence on the pathogenesis, gut–liver axis, and multidisciplinary management of MASLD within the ...
Beom Kyung Kim
wiley   +1 more source

Circulating Omega‐3 Fatty Acids and Cardiometabolic Outcomes: A Systematic Review of Publications From UK Biobank

Lipids, EarlyView.
ABSTRACT Studies have shown that omega‐3 fatty acids may protect against cardiovascular diseases (CVDs) and related metabolic conditions. UK Biobank is a large cohort study that includes data on plasma omega‐3 fatty acids at study entry and health outcomes during the follow‐up period.
Warda Tul Firdous, Philip C. Calder
wiley   +1 more source

Precision Medicine in Neurodegeneration with Brain Iron Accumulation (NBIA) Disorders: An Update on Emerging Treatments

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Neurodegeneration with Brain Iron Accumulation (NBIA) is a heterogeneous group of heritable, mostly recessive, progressive neurodegenerative diseases characterized by iron deposition in the basal ganglia and brainstem. There are no solid global epidemiological data on prevalence and incidence of NBIA subtypes, but registry data and ...
Susanne A. Schneider, Divyani Garg, Vassilena Iankova, Thomas Klopstock   +3 more
wiley   +1 more source

Effects of n-3 PUFA and n-6 PUFA on plasma lipids, bleeding time, prothrombin time, and liver cholesterol in the gerbil [PDF]

, 1988
This dissertation research assessed the effects of n-3 and n-6 PUFA fed in varying combinations on plasma lipids, bleeding time, prothrombin time, and liver cholesterol in 90 adult male gerbils. Gerbils (15 per group) were randomly assigned to one of six
Dunn, Patricia Carolyn, NC DOCKS at The University of North Carolina at Greensboro   +1 more
core  

Toxicity Differences Between Microplastics and Nanoplastics in Organs: From Molecular Mechanisms to Potential Therapeutic Strategies

Med Research, EarlyView.
This review systematically compares the size‐dependent toxicity of microplastics and nanoplastics in the intestine, liver, kidney, lung, and brain. Particle size determines bioavailability, barrier penetration, and injury mechanisms. Because of their small size and high surface reactivity, NPs readily cross the intestinal epithelium and blood–brain ...
Yixian Cheng, Junjie Chen, Rui Fu, Jiawei Zhang, Jianguang Jia, Wei Wang, Zheng Zhang, Peng Zhang, Haosong Chen, Huake Cao, Gang Li, Weiwei Sheng, Ting Li, Bo Chen, Guodong Cao   +14 more
wiley   +1 more source

Dietary Fatty Acids, Cardiovascular Disease, and Life Expectancy Among Adults With Adverse Mental Health‐Related Characteristics: A Cohort‐Based Target Trial Emulation Study

Med Research, EarlyView.
This study highlights the cardiovascular and longevity benefits of dietary n‐3 PUFAs in individuals with adverse mental health‐related characteristics, particularly ALA and EPA. The target trial emulation framework further provides evidence, revealing EPA and DHA are associated with a lower early‐onset CVD risk in loneliness, while ALA and EPA are ...
Li Chen, Feipeng Cui, Tianqi Tan, Qi Wu, Ying Zhao, Huimin Chen, Zhilei Shan, Yuhan Tang, Xiao Yu, Qianchun Deng   +9 more
wiley   +1 more source

Baicalin Induces Ferroptosis in Breast Cancer Through a Novel STAT3/HO‐1/GPX4 Regulatory Axis

Phytotherapy Research, EarlyView.
BA inhibits STAT3 phosphorylation and activation in BC cells, accompanied by decreased expression of HO‐1 and GPX4. Reduced GPX4 activity impairs lipid peroxide clearance, promoting ROS accumulation and lipid peroxidation, which ultimately triggers ferroptosis and inhibits cell proliferation.
Tingting Guo, Fansu Meng, Detang Li, Maciej Mazur, Alicia Marcelina Díaz García, Mulazim Hussain Asim, Zhong Chen, Yiqi Chen, Yixuan Lin, Zhenjiang Yang, Panpan Wang, Yu Cai   +11 more
wiley   +1 more source

Integrative Approaches in Cardiovascular Disease: The Role of Nutraceuticals in Heart Failure, Atrial Fibrillation, and Related Conditions

Phytotherapy Research, EarlyView.
Schematic representation of the shared pathophysiological mechanisms underlying heart failure (HF) and atrial fibrillation (AF), including inflammation, oxidative stress, endothelial dysfunction, and fibrosis. The figure highlights the clinical and mechanistic convergence of conventional pharmacological therapies and selected nutraceuticals in ...
Laura Beatrice Mattioli, Ivan Corazza, Roberta Budriesi, Luca Camarda, Maria Carelli, Alberto Spadotto, Igor Diemberger   +6 more
wiley   +1 more source

PUFA/pufa index: guide for clinical assessment of the consequences of untreated caries lesions

Given the severe consequences of untreated dental caries, such as dental emergencies and hospitalizations, an illustrated clinical guide on the pufa/PUFA index was developed to assist dentists in identifying and managing oral lesions caused by this ...
Tristão, Sylvia Karla de Paiva Cabral, Avelino, Maíty Gonçalves, Primo, Laura Guimarães, Silva, Kenderson Santos, Souza, Ivete Pomarico Ribeiro de, Pomarico, Luciana   +5 more
core  

Recent Advances in Microalgae‐Based Functional Coatings and Films for Food Packaging Applications: Opportunities and Challenges

Packaging Technology and Science, EarlyView.
Microalgae‐derived bioactive compounds exhibit strong antioxidant and antimicrobial properties and can be incorporated into edible coatings to enhance food quality and shelf life. These materials offer sustainable, biodegradable alternatives to conventional packaging, with promising potential for future scalable food applications.
Madhu Gaidher, Nidhi Bhardwaj, Sachin Sharma, Akanksha Singh, Kanika Dulta, P. K. Chauhan, Pooja Yadav, Hira Iqbal, Helen Onyeaka, Soumya Ghosh   +9 more
wiley   +1 more source