Results 171 to 180 of about 148,322 (338)

The role of iron in normal and impaired testicular function

Andrology, EarlyView.
Abstract Iron plays a critical role in testicular physiology, impacting spermatogenesis, testosterone production, and overall testicular function. Iron homeostasis is maintained through systemic and cellular regulatory mechanisms, including hepcidin‐mediated systemic iron control and the iron‐responsive element/iron regulatory protein (IRE/IRP) system ...
Aileen Harrer, Esther G. Meyron‐Holtz, Andreas Meinhardt   +2 more
wiley   +1 more source

Mitochondria ATP Pro‐Ferroptosis by Adjusting the Conversion of PUFA to PUFA‐PLs

MedComm – Oncology
ABSTRACTFerroptosis is a form of iron‐dependent regulated necrosis characterized by the abnormal accumulation of peroxidized phospholipids containing polyunsaturated fatty acids (PUFA‐PLs). The conversion of PUFA to PUFA‐CoA is critical for the synthesis of PUFA‐PLs and is reliant on ATP, yet the role of mitochondrial ATP production in regulating ...
Chaoyi Xia, Lianchao Gao, Jingshu Min, Caiyun Fu   +3 more
openaire   +1 more source

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

British Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli, Emanuela Micioni Di Bonaventura, Giacomo Einaudi, Gustavo Provensi, Alessia Costa, Claudio D'Addario, Carlo Cifani, Maria Vittoria Micioni Di Bonaventura   +7 more
wiley   +1 more source

International Society of Sports Nutrition Position Stand: Long-Chain Omega-3 Polyunsaturated Fatty Acids

Journal of the International Society of Sports Nutrition
Position Statement: The International Society of Sports Nutrition (ISSN) presents this position based on a critical examination of the literature surrounding the effects of long-chain omega-3 polyunsaturated fatty acid (ω-3 PUFA) supplementation on ...
Ralf Jäger, Jeffery L. Heileson, Sidney Abou Sawan, Broderick L. Dickerson, Megan Leonard, Richard B. Kreider, Chad M. Kerksick, Stephen M. Cornish, Darren G. Candow, Dean M. Cordingley, Scott C. Forbes, Grant M. Tinsley, Tindaro Bongiovanni, Roberto Cannataro, Bill I. Campbell, Shawn M. Arent, Jeffrey R. Stout, Douglas S. Kalman, Jose Antonio   +18 more
doaj   +1 more source

LCN2‐ACOD1 Signalling Affects the Post‐Injury Regeneration of Skeletal Muscle Through Mediating Ferroptosis

Cell Proliferation, EarlyView.
LCN2 mediates the suppression of C2C12 myoblast proliferation and myotube formation via erastin‐induced ferroptosis. Mechanistically, the LCN2‐ACOD1 axis regulates skeletal muscle growth via mitochondria‐associated ferroptosis, providing a theoretical basis for the prevention and therapy of muscle‐related diseases.
Xiaojing Hao, Hongwei Shi, Di Wu, Rui Liang, Tong Zhao, Wen Sun, Yue Wang, Xiuju Yu, Xiaomao Luo, Yi Yan, Jiayin Lu, Haidong Wang, Juan Wang   +12 more
wiley   +1 more source

Omega-3-PUFA, omega-6-PUFA and mitochondrial dysfunction in relation to remodelling

, 2020
Metabolic syndrome may be a disease of the brain related to Western diet-induced proinflammatory damage of the arcuate nucleus and POMC neurons in the brain, as well as to damage of beta cells in the pancreas. Consumption of a Western diet and eating late at night can double the adverse effects of diet by causing systemic inflammation and damage to the
Singh R.B., Gvozdjáková A., Singh J., Shastun S., Dhalla N.S., Pella D., Fedačko J., Cornélissen G.   +7 more
openaire   +1 more source

Insights Into Macrophage Ferroptosis: Implications for Atherosclerosis

Cell Proliferation, EarlyView.
Macrophage ferroptosis drives atherosclerosis by enhancing oxidative stress and inflammation, accelerating plaque progression and instability. Targeting macrophage ferroptosis presents a promising therapeutic strategy for atherosclerosis treatment.
Xiehui Chen, Xiangbo Liu, Changchun Zeng
wiley   +1 more source

Flooding affects fluctuating asymmetry but not growth of a riparian orbweaving spider

Ecological Entomology, EarlyView.
In a mesocosm experiment we assessed the impact of flood on aquatic insect emergence and on spider development using geometric morphometric analysis of fluctuating asymmetry. We observed 45% higher emergence in flooded mesocosm throughout the season. Spiders did not grow bigger but exhibited ~15% lower fluctuating asymmetry than in controls.
Stephane Mutel, Martin H. Entling, Ken M. Mauser, Federica Spani, Celia Thomas, Collins Ogbeide, Mirco Bundschuh, Franziska Fiolka, Franziska Middendorf, Ralf Schulz, Alessandro Manfrin   +10 more
wiley   +1 more source

Fish and omega-3 intake and health in older people [PDF]

, 2018
Marshall, Skye, Van der Meij, Barbara S
core   +1 more source

Update on diagnosis, nonpharmacological treatment and prevention of Equine Gastric Ulcer Syndrome (EGUS)

Equine Veterinary Education, EarlyView.
Summary The term Equine Gastric Ulcer Syndrome (EGUS) has been used since 1999. As there are important differences, the terms Equine Squamous Gastric Disease (ESGD) and Equine Glandular Gastric Disease (EGGD) were introduced in 2015. Risk factors like dietary management, training regimens and drug side effects, as described for NSAIDs, predispose ...
R. Lensing, A. K. Barton
wiley   +1 more source