Results 191 to 200 of about 114,514 (356)
The Journal of Pathology, EarlyView.Abstract Acquired lipodystrophy in the dermal white adipose tissue (DWAT) is an early phenotype of skin fibrosis, followed by the accumulation of extracellular matrix (ECM). Lipodystrophy syndromes are estimated to affect 1 in 20,000 people and are associated with metabolic comorbidities.
Suneeti R Madhavan +10 more
wiley +1 more source
Omega-3-PUFA, omega-6-PUFA and mitochondrial dysfunction in relation to remodelling
, 2020 Metabolic syndrome may be a disease of the brain related to Western diet-induced proinflammatory damage of the arcuate nucleus and POMC neurons in the brain, as well as to damage of beta cells in the pancreas. Consumption of a Western diet and eating late at night can double the adverse effects of diet by causing systemic inflammation and damage to the
Singh R.B. +7 more
openaire +1 more source
Pediatric Discovery, EarlyView.This study found that the metabolomic signature of umbilical venous cord blood in congenital heart disease (CHD) differs from that of healthy monozygotic (MZ) co‐twins. Dysregulation of metabolic pathways like glucose, lipid, and amino acid metabolism, along with altered metabolites, helps understand CHD predisposition.
Fang Xiang +6 more
wiley +1 more source
When Fat Goes Astray: Your Liver and Pancreas Get Into Trouble
Portal Hypertension &Cirrhosis, EarlyView.Metabolic dysfunction‐associated steatotic liver disease (MASLD) and intrapancreatic fat deposition (IPFD) are both common manifestations of ectopic fat accumulation. Although they share multiple risk factors, they also show notable differences in pathological features, standardization of diagnosis, and research maturity.
Yuying Chen +5 more
wiley +1 more source
Isothiocyanates as Ferroptosis Inducers to Promote Cancer Cell Death
Phytotherapy Research, EarlyView.ABSTRACT Cancer remains a leading cause of global mortality, with the therapeutic efficacy of anticancer drugs often hampered by late diagnosis and the development of chemotherapy resistance. Ferroptosis is an iron‐dependent form of regulated non‐apoptotic cell death driven by lipid peroxidation.
Valentina Citi +6 more
wiley +1 more source
Environmental Toxicology, EarlyView.ABSTRACT Perfluorooctane sulfonate (PFOS), a perfluoroalkyl substance (PFAS), is characterized by a long, fluorinated carbon chain which makes it ideal for oil‐ and water‐repellent products but detrimental for the environment, where it persists and accumulates in organisms.
Anna L. Thornton +5 more
wiley +1 more source
Environmental Toxicology, EarlyView.ABSTRACT Freshwater ecosystems are increasingly impacted by anthropogenic pollutants, including the widely used herbicide metolachlor (MET) and cigarette butt (CB) litter. Parasites represent an additional biotic stressor that can modulate pollutant effects on their hosts.
Erika Berenice Martínez‐Ruiz +3 more
wiley +1 more source
Oral Health on Sal, Cape Verde: A Population-Based, Cross-Sectional Study. [PDF]
Int Dent JVolgenant CMC +3 more
europepmc +1 more source