Results 181 to 190 of about 114,514 (356)
Lipids, EarlyView.ABSTRACT The effects of fish oil supplementation on omega‐3 (n‐3) polyunsaturated fatty acids, particularly intermediates between eicosapentaenoic acid (EPA, 20:5n‐3) and docosahexaenoic acid (DHA, 22:6n‐3), that may provide valuable metabolic information, have not been fully characterized in older populations.
David C. R. Ku +4 more
wiley +1 more source
, 2016 Backgrountl: So fa1 there is no data of to what extent the clinical consequences of untreated dental caries have impacted the quality of life of the school age children of 6 -12 years old in the Province of Sumatera Utara. Quality of life is one of the
Molek, Molek
core
Effects of n-3 PUFA and n-6 PUFA on plasma lipids, bleeding time, prothrombin time, and liver cholesterol in the gerbil [PDF]
, 1988 This dissertation research assessed the effects of n-3 and n-6 PUFA fed in varying combinations on plasma lipids, bleeding time, prothrombin time, and liver cholesterol in 90 adult male gerbils. Gerbils (15 per group) were randomly assigned to one of six
Dunn, Patricia Carolyn +1 more
core
Molecular Carcinogenesis, EarlyView.ABSTRACT Owing to their robust antioxidant defense mechanisms, cancer stem‐like cells (CSCs) maintain a low level of oxidative stress, which is crucial for preserving stemness and pluripotency. Therefore, agents that either directly generate reactive oxygen species (ROS) or inhibit the antioxidant defense systems can selectively induce oxidative cell ...
Xueqing Liang +4 more
wiley +1 more source
Preprint: Binding of PUFA stabilizes a conductive state of the selectivity filter in IKs channels
In cardiomyocytes, the KCNQ1/KCNE1 channel complex mediates the slow delayed-rectifier current (IKs), pivotal during the repolarization phase of the ventricular action potential. Mutations in IKs cause Long QT Syndrome (LQTS), a syndrome with a prolonged
Kevin P. Cunningham +8 more
core +1 more source
Movement Disorders, EarlyView.Abstract Background Emerging evidence indicates that dysregulation of monounsaturated fatty acids (MUFAs), synthesized by the enzyme stearoyl‐coenzyme A desaturase (SCD), impacts on α‐synuclein pathology in the Parkinson's disease (PD) brain. Objective The objective of this study was to analyze SCD and MUFA‐enriched lipids in the periphery of patients ...
Finula I. Isik +5 more
wiley +1 more source
Ferroptosis and Its Emerging Role in Gestational Diabetes Mellitus
Medicine Advances, EarlyView.Ferroptosis contributes to the development of gestational diabetes mellitus (GDM) through iron overload, lipid peroxidation, and antioxidant system disruption. These changes impair adipocyte and β‐cell function, promoting insulin resistance and hyperglycemia.
Jinfeng Xu +4 more
wiley +1 more source
New Plant Protection, EarlyView.We developed a genome‐integrated CRISPR/Cas12a system for Xenorhabdus budapestensis XBD8, which enables precise deletion or replacement of DNA fragments ranging from 379 to 45,168 bp, with a success rate exceeding 90%. Application of this tool for the dynamic regulation of fabclavine‐8 biosynthesis resulted in a 1.90‐fold increase in production ...
Wenfeng Gan +4 more
wiley +1 more source
PUFAs in sickle cell disease [PDF]
The American Journal of Clinical Nutrition, 2013 openaire +2 more sources
Oikos, EarlyView.Nutrients, including vital organic compounds, vary in availability across ecosystems, with the potential to act as a source of selection for traits that increase nutrient acquisition and biosynthesis. Compared to freshwaters, marine ecosystems are richer in the omega‐3 long‐chain polyunsaturated fatty acid (n‐3 LC‐PUFA) docosahexaenoic acid (DHA ...
Cornelia W. Twining +12 more
wiley +1 more source