Results 281 to 290 of about 148,322 (338)

Lipidomic Analysis of Plasma Extracellular Vesicles from Adiponectin Deficient Mice or Metabolic Syndrome Patients Reveals Pro‐Oxidative and Pro‐Inflammatory Lipid Signatures Correlating with Metabolic Dysfunction

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 2, February 2026.
Adiponectin deficiency remodels the lipid composition of plasma extracellular vesicles (EV), enriching polyunsaturated phospholipids and reducing lysophospholipids. These remodelled EV impact oxidative, inflammatory and metabolic function in recipient cells.
Sungji Cho   +13 more
wiley   +1 more source

Targeting C12ORF49‐Mediated Ferroptosis in Hepatocellular Carcinoma

open access: yesJGH Open, Volume 10, Issue 2, February 2026.
ABSTRACT Hepatocellular carcinoma (HCC) remains a leading cause of cancer‐related mortality worldwide, underscoring the urgent need for novel therapeutic strategies. Recent studies have highlighted the pivotal role of ferroptosis, an iron‐dependent form of regulated cell death driven by lipid peroxidation, in cancer biology.
Yuexin Liu   +4 more
wiley   +1 more source

Developmental outcomes after soybean oil vs mixed‐oil intravenous lipid emulsions in neonates: A secondary analysis of a clinical trial

open access: yesJournal of Parenteral and Enteral Nutrition, Volume 50, Issue 2, Page 228-235, February 2026.
Abstract Background Fatty acids make up a significant portion of brain mass. The choice of lipid injectable emulsion alters a patient's fatty acid profile. In neonates with intestinal failure dependent on parenteral nutrition, this is particularly concerning given their rapid brain development. Methods We randomly assigned 24 infants to receive soy oil
Katie A. Huff, Charles Vanderpool
wiley   +1 more source

Long-chain polyunsaturated fatty acid lipid and oxylipin alterations in postoperative delirium after cardiac surgery. [PDF]

open access: yesJ Lipid Res
Wiredu K   +9 more
europepmc   +1 more source

Oxidative Stress: Molecular Mechanisms, Diseases, and Therapeutic Targets

open access: yesMedComm, Volume 7, Issue 2, February 2026.
Oxidative stress occurs when the reactive oxygen species (ROS) production overwhelms the ROS scavenging, which lead to genomic instability, epigenetic regulation, proteostasis imbalance, and lipid peroxidation, subsequently causing the occurrence and development of numerous diseases. ABSTRACT Although the physiological level of reactive oxygen species (
Yi Qin   +10 more
wiley   +1 more source

High concentrations of polyunsaturated n-3 fatty acids in serum are inversely associated with risk of future incident venous thromboembolism - the HUNT cohort study. [PDF]

open access: yesAm J Clin Nutr
Johansson M   +10 more
europepmc   +1 more source

Bone Metastasis: Molecular Mechanisms, Clinical Management, and Therapeutic Targets

open access: yesMedComm, Volume 7, Issue 2, February 2026.
This figure emphasizes current understanding of the regulatory networks, approach of diagnose, available preclinical models and clinical management of bone metastasis. to guide future therapeutic development. A deep understanding of these aspects enables the prevention of bone metastasis and the implementation of effective therapeutic strategies ...
Jingyuan Wen   +5 more
wiley   +1 more source

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