Results 81 to 90 of about 148,322 (338)

Fatty acid bioconversion in harpacticoid copepods in a changing environment : a transcriptomic approach [PDF]

, 2020
By 2100, global warming is predicted to significantly reduce the capacity of marine primary producers for long-chain polyunsaturated fatty acid (LC-PUFA) synthesis.
Boyen, Jens, De Troch, Marleen, Fink, Patrick, Hablützel, Pascal I., Mensens, Christoph   +4 more
core   +1 more source

n-3 PUFA Supplementation Alters Retinal Very-Long-Chain-PUFA Levels and Ratios in Diabetic Animal Models.

Molecular Nutrition & Food Research, 2019
SCOPE Long chain (LC)-PUFAs act as precursors for special class of retinal lipids known as Very-long-chain (VLC)-PUFAs and the effect of diabetes on retinal VLC-PUFA levels has been unexplored. In order to understand the supplemental effect of n-3 PUFAs,
Aruna Gorusupudi, Fu-Yen Chang, Kelly Nelson, G. Hageman, P. Bernstein   +4 more
semanticscholar   +1 more source

CRISPLD2 Attenuates Intervertebral Disc Degeneration by Suppressing Oxidative Stress‐Induced Ferroptosis through the miR‐548I‐IL17A Axis

Advanced Science, EarlyView.
This study identifies CRISPLD2 as a key protector against IVDD. By regulating ferroptosis through the CRISPLD2–miR‐548I–IL17A axis, CRISPLD2 maintains NPCs homeostasis and reduces oxidative stress. Restoring CRISPLD2 expression effectively alleviates disc degeneration and highlights a promising therapeutic strategy for discogenic low back pain ...
Yangyang Shi, Fudong Li, Tianyi Zhao, Kaiqiang Sun, Danying Zhang, Chen Yan, Ximing Xu, Jingchuang Sun, Xulin Hu, Xin Yong, Jiangang Shi, Yuan Wang   +11 more
wiley   +1 more source

Dietary chia seed (Salvia hispanica L.) rich in a-linolenic acid improves adiposity and normalises hypertriacylglycerolaemia and insulin resistance in dyslipaemic rats [PDF]

, 2009
The present study investigates the benefits of the dietary intake of chia seed (Salvia hispanica L.) rich in α-linolenic acid and fibre upon dyslipidaemia and insulin resistance (IR), induced by intake of a sucrose-rich (62.5 %) diet (SRD).
Chicco, Adriana Graciela, D'alessandro, Maria Eugenia Guadalupe, Hein, Gustavo Juan, Lombardo, Yolanda B., Oliva, Maria Eugenia   +4 more
core   +1 more source

Higher PUFA and n-3 PUFA, conjugated linoleic acid, α-tocopherol and iron, but lower iodine and selenium concentrations in organic milk: a systematic literature review and meta- and redundancy analyses

British Journal of Nutrition, 2016
Demand for organic milk is partially driven by consumer perceptions that it is more nutritious. However, there is still considerable uncertainty over whether the use of organic production standards affects milk quality.
D. Średnicka-Tober, Marcin Barański, C. Seal, R. Sanderson, C. Benbrook, H. Steinshamn, J. Gromadzka-Ostrowska, E. Rembiałkowska, K. Skwarło‐Sońta, M. Eyre, G. Cozzi, M. K. Larsen, T. Jordon, U. Niggli, T. Sakowski, P. Calder, G. Burdge, S. Sotiraki, A. Stefanakis, S. Stergiadis, H. Yolcu, E. Chatzidimitriou, G. Butler, G. Stewart, C. Leifert   +24 more
semanticscholar   +1 more source

Creating Cell‐Based Hybrid Noodles for Sustainable and Nutrient‐Balanced Diets via a Serum‐Free and Animal‐Free 3D Co‐Differentiation System

Advanced Science, EarlyView.
This study develops a 3D co‐culture and co‐differentiation system for porcine muscle stem cells (pMuSCs) and mesenchymal stem cells (pMSCs) on edible starch‐based scaffolds. The system simultaneously generates myotubes and adipocytes without using serum or chemical inducers.
Xin Guan, Luyi Wang, Wanqiang Sun, Yiwei Feng, Dandan Wang, Haohao Tang, Zhenwu Ma, Guocheng Du, Jian Chen, Jingwen Zhou   +9 more
wiley   +1 more source

First-Trimester Serum n-3/n-6 Fatty Acids Predict Large-for-Gestational-Age Risk: A Nested Case-Control Study. [PDF]

Matern Child Nutr
ABSTRACT Polyunsaturated fatty acids (PUFAs) are critical for fetal development during pregnancy. This study evaluates the association between maternal serum n‐3 and n‐6 PUFAs in early pregnancy and the risk of large‐for‐gestational‐age (LGA) infants.
Cai X, Zhu H, Liang N, Zhu Y, Dang Q, Gao M, Yu H.   +6 more
europepmc   +2 more sources

Immune response of cows fed polyunsaturated fatty acids under high ambient temperatures [PDF]

, 2009
The aim of the experiment was to determine the effects of 2 different fat supplementations on immune functions of dairy cows under high ambient temperatures.
Albenzio, M, Caroprese, M, Entrican, G, Marzano, A, Sevi, A, Wattegedera, S   +5 more
core   +1 more source

High Dietary ω-6:ω-3 PUFA Ratio Is Positively Associated with Excessive Adiposity and Waist Circumference

Obesity Facts, 2018
Objective: The aim of this study was to analyze dietary ω-6:ω-3 polyunsaturated fatty acid (PUFA) ratio and its association with adiposity and serum adiponectin levels in a Mexican population.
Nathaly Torres-Castillo, J. Silva-Gomez, W. Campos-Pérez, Elisa Barrón-Cabrera, I. Hernández-Cañaveral, Mary L. García-Cazarín, Y. Márquez-Sandoval, Karina González-Becerra, Carlos Barron-Gallardo, E. Martínez-López   +9 more
semanticscholar   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source