Results 101 to 110 of about 80,002 (308)

A bioinspired catalytic nanoplatform for ferroptosis‐immunotherapy synergy in metastatic cancer

open access: yesBMEMat, EarlyView.
The bioinspired nanoplatform MnMSN@MnP‐PEG co‐delivers manganese peroxidase and manganese ions to synergistically induce immunogenic ferroptosis and activate the cGAS‐STING pathway, eliciting potent antitumor immunity against primary and metastatic tumors.
Panpan Xue   +8 more
wiley   +1 more source

Assessing clinical sequelae of untreated caries among 5-, 12-, and 15-year-old school children in ambala district: A cross-sectional study

open access: yesJournal of Indian Society of Pedodontics and Preventive Dentistry, 2018
Background: Dental caries is a public health problem globally, especially in children. Thus, it is important to quantify its clinical consequences in terms of its prevalence and severity. Aim: This study aims to assess the prevalence and severity of oral
Jasneet Sudan   +2 more
doaj   +1 more source

PUFAs and IBD [PDF]

open access: yesInflammatory Bowel Diseases, 2017
Livia, Lindoso   +2 more
openaire   +2 more sources

Heat stress in spermatogenesis: a redox‐dependent decision network linking ROS, autophagy, and regulated cell death

open access: yesBiological Reviews, EarlyView.
ABSTRACT Heat stress (HS) is an increasing threat to male reproductive health, disrupting spermatogenesis through complex and interdependent cellular responses within the seminiferous epithelium. Although excessive reactive oxygen species (ROS) production is a hallmark of HS, ROS also act as central regulators of cell fate decisions beyond their role ...
Ribrio Ivan Tavares Pereira Batista
wiley   +1 more source

Dietary supplementation with fish gelatine modifies nutrient intake and leads to sex-dependent responses in TAG and C-reactive protein levels of insulin-resistant subjects

open access: yesJournal of Nutritional Science, 2012
Previous studies have shown that fish protein, as well as marine n-3 PUFA, may have beneficial effects on cardiovascular risk profile. The objectives of this study were to investigate the combined effects of fish gelatine (FG) and n-3 PUFA ...
Éliane Picard-Deland   +10 more
doaj   +1 more source

Pparγ Is Involved in the Transcriptional Regulation of Liver LC-PUFA Biosynthesis by Targeting the Δ6Δ5 Fatty Acyl Desaturase Gene in the Marine Teleost Siganus canaliculatus [PDF]

open access: yes, 2019
As the first marine teleost demonstrated to have the ability of long-chain polyunsaturated fatty acids (LC-PUFA) biosynthesis from C18 PUFA precursors, the rabbitfish Siganus canaliculatus provides us a unique model for clarifying the regulatory ...
You, Cuihong   +6 more
core   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang   +7 more
wiley   +1 more source

The Potential Benefits and Mechanism of Action of Tropical Nuts Against Metabolic Syndrome: A Literature Review

open access: yesAmerta Nutrition
Background: Metabolic syndrome is a significant risk factor for both type 2 diabetes mellitus and cardiovascular disease, with a high prevalence in Asia Pacific, particularly in Indonesia.
Amalia Rani Setyawati   +2 more
doaj   +1 more source

The correlation between untreated caries and the nutritional status of 6–12 years old children in the Medan Maimun and Medan Marelan sub-district

open access: yesDental Journal, 2018
Background: In Indonesia, dental caries constitute one of the most common dental health problems in children. Untreated dental caries will cause both pain and inconvenience when eating, resulting in a reduced appetite which can negatively affect the Body
Siti Salmiah   +3 more
doaj   +1 more source

Intestinal microbiome alterations in pediatric epilepsy: Implications for seizures and therapeutic approaches

open access: yesEpilepsia Open, EarlyView.
Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza   +4 more
wiley   +1 more source

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