Results 81 to 90 of about 114,514 (356)

Single‐Cell Reveal GALNT7‐Dependent Ferroptosis Suppression as a Mechanism of Immunotherapy Resistance in Non‐Small Cell Lung Cancer

open access: yesAdvanced Science, EarlyView.
Integrated clinical and mechanistic analyses identify GALNT7 as a ferroptosis‐suppressive regulator associated with immunotherapy resistance in non‐small cell lung cancer. GALNT7 depletion promotes lipid peroxidation, mitochondrial dysfunction, and ferroptosis, enhances CD8+ T‐cell activation and IFN‐γ production, and sensitizes tumors to PD‐1 blockade,
Jiadi Gan   +11 more
wiley   +1 more source

Alleviation of reactive oxygen species enhances PUFA accumulation in Schizochytrium sp. through regulating genes involved in lipid metabolism

open access: yesMetabolic Engineering Communications, 2018
The unicellular heterotrophic thraustochytrids are attractive candidates for commercial polyunsaturated fatty acids (PUFA) production. However, the reactive oxygen species (ROS) generated in their aerobic fermentation process often limits their PUFA ...
Sai Zhang   +6 more
semanticscholar   +1 more source

A Modular PLUG‐IN Photosynthetic Chassis With Tunable Thermal Control for Mammalian Systems

open access: yesAdvanced Science, EarlyView.
This work establishes a “plug‐in” chassis compatible with mammalian systems that synchronizes growth, production, and cell‐wall re‐configuration, providing a versatile platform for photosynthetic bioproduction and microalgal synthetic biology. ABSTRACT Microalgae are promising photosynthetic platforms for high‐value compounds, yet their industrial use ...
Qinhua Gan   +13 more
wiley   +1 more source

Nutritional regulation of long-chain PUFA biosynthetic genes in rainbow trout (Oncorhynchus mykiss) [PDF]

open access: yes, 2016
Most studies on dietary vegetable oil in rainbow trout (Oncorhynchus mykiss) have been conducted on a background of dietary EPA (20 : 5n-3) and DHA (22 : 6n-3) contained in the fishmeal used as a protein source in aquaculture feed. If dietary EPA and DHA
Collins, Robert O   +9 more
core   +1 more source

Effects of dietary PUFA patterns and FADS genotype on breast milk PUFAs in Chinese lactating mothers

open access: yesGenes & Nutrition, 2023
Abstract Background Breastfeeding affects the growth and development of infants, and polyunsaturated fatty acids (PUFAs) play a crucial role in this process. To explore the factors influencing the PUFA concentration in breast milk, we conducted research on two aspects: dietary fatty acid patterns and single nucleotide ...
Xu, Wen-Hui   +7 more
openaire   +2 more sources

Influence of dietary linseed and sunflower oil on sensory characteristics of rainbow trout (Oncorhynchus mykiss)

open access: yesCzech Journal of Animal Science, 2006
This study describes the effects of dietary linseed and sunflower oil on the sensory characteristics of rainbow trout (Oncorhynchus mykiss) fillets. Rainbow trout were fed a diet containing either 2.5% or 5% of linseed or sunflower oil or 5% mixture of ...
Z. Drobná   +3 more
doaj   +1 more source

Dietary n-3 PUFA May Attenuate Experimental Colitis

open access: yesMediators of Inflammation, 2018
Background Inflammatory bowel diseases (IBD) occurred in genetically predisposed people exposed to environmental triggers. Diet has long been suspected to contribute to the development of IBD.
C. Charpentier   +9 more
semanticscholar   +1 more source

Drosophila lacks C20 and C22 PUFAs [PDF]

open access: yesJournal of Lipid Research, 2010
Drosophila melanogaster has been considered a model organism for investigating human diseases and genetic pathways. Whether Drosophila is an ideal model for nutrigenomics, especially for FA metabolism, however, remains to be illustrated. The aim of this study was to examine the metabolism of C20 and C22 PUFAs in Drosophila.
Li Rong Shen   +8 more
openaire   +3 more sources

The Effects of Enzyme Pretreatment Extraction on Lipid Recovery With Normal Phase HPLC

open access: yesJournal of the American Oil Chemists' Society, EarlyView.
ABSTRACT With the increasing interest in the commercialization of microalgal fermentation‐based products, sustainable and efficient oil extraction methods have been developed for manufacturing and analytical testing. Due to the variability and resilience of micro‐algae cell walls, traditional lipid extraction methods such as Folch and Bligh and Dyer ...
Zhehan Jiang   +4 more
wiley   +1 more source

Influence of n-3 and n-6 polyunsaturated fatty acids on sensory characteristics of chicken meat

open access: yesCzech Journal of Animal Science, 2008
The relationship between different levels of n-6 and n-3 PUFA in chicken breast and thigh meat and sensory characteristics of meat was studied. Chickens were fed diets containing 1, 3, 5 or 7 percent of oil made of seeds either of the linseed cultivar ...
J. Zelenka   +2 more
doaj   +1 more source

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