Echocardiographic assessment of pulmonary hypertension: a guideline protocol from the British Society of Echocardiography. [PDF]
Pulmonary hypertension is defined as a mean arterial pressure of ≥25 mmHg as confirmed on right heart catheterisation. Traditionally, the pulmonary arterial systolic pressure has been estimated on echo by utilising the simplified Bernoulli equation from ...
Augustine, DX +20 more
core +3 more sources
Incident pulmonary arterial hypertension associated with Bosutinib
Pulmonary arterial hypertension is associated with tyrosine kinase inhibitors used in the treatment of chronic myeloid leukemia. Dasatinib is a known cause of drug-induced pulmonary arterial hypertension.
Shaun Yo +3 more
doaj +1 more source
Impact of the updated hemodynamic definitions on diagnosis rates of pulmonary hypertension
We evaluated whether updated pulmonary hypertension definitive criteria proposed in sixth World Symposium on Pulmonary Hypertension had an impact on diagnosis of overall pulmonary hypertension and pre-capillary and combined pre- and post-capillary ...
Seda Tanyeri +15 more
doaj +1 more source
Transcription factors and potential therapeutic targets for pulmonary hypertension
Pulmonary hypertension (PH) is a refractory and fatal disease characterized by excessive pulmonary arterial cell remodeling. Uncontrolled proliferation and hypertrophy of pulmonary arterial smooth muscle cells (PASMCs), dysfunction of pulmonary arterial ...
Liu Yang +5 more
doaj +1 more source
Plasma proteome analysis in patients with pulmonary arterial hypertension: an observational cohort study [PDF]
BackgroundIdiopathic and heritable pulmonary arterial hypertension form a rare but molecularly heterogeneous disease group. We aimed to measure and validate differences in plasma concentrations of proteins that are associated with survival in patients ...
Abdul-Salam +29 more
core +1 more source
Quantification of Pulmonary Arterial Wall Distensibility Using Parameters Extracted from Volumetric Micro-CT Images [PDF]
Stiffening, or loss of distensibility, of arterial vessel walls is among the manifestations of a number of vascular diseases including pulmonary arterial hypertension.
Dawson, Christopher A +3 more
core +2 more sources
Clinical heterogeneity of Pulmonary Arterial Hypertension associated with variants in TBX4.
BACKGROUND:The knowledge of hereditary predisposition has changed our understanding of Pulmonary Arterial Hypertension. Genetic testing has been widely extended and the application of Pulmonary Arterial Hypertension specific gene panels has allowed its ...
Ignacio Hernandez-Gonzalez +15 more
doaj +1 more source
Role of prostacyclin in pulmonary hypertension [PDF]
Date of Acceptance: 11/12/2014 This is an open access article distributed under the terms of the Creative Commons Attribution license CC BY-4.0, which permits unrestricted use, distribution and reproduction in any medium, provided the original work is ...
Ali FY +8 more
core +3 more sources
Anticoagulation in pulmonary arterial hypertension: a decision analysis
Systemic anticoagulation may be beneficial in pulmonary arterial hypertension, but there is no randomized clinical trial data to guide therapeutic decision making, and current guidelines do not account for patient preferences or quality of life. Decision
Arun Jose +2 more
doaj +1 more source
Matrix metalloproteinase 7 in diagnosis and differentiation of pulmonary arterial hypertension
Pulmonary arterial hypertension is a severe disease for which diagnosis often is delayed. Matrix metalloproteinases have been suggested to play a role in vascular remodeling and pulmonary hypertension development. Our aim was therefore to investigate the
Mattias Arvidsson +3 more
doaj +1 more source

