Results 11 to 20 of about 392,188 (298)

The marginated pool [PDF]

, 2002
The pulmonary circulation harbors a large intravascular reservoir of leukocytes refered to as the Marginated Pool. This marginated pool is balanced by propeling and retaining forces acting on leukocytes during their passage through the pulmonary ...
Goetz, Alwin Eduard, Kuebler, Wolfgang M.   +1 more
core   +1 more source

Circular RNAs in pulmonary hypertension: Emerging biological concepts and potential mechanism

Animal Models and Experimental Medicine, 2022
Circular RNAs (circRNAs) are endogenous RNAs with a covalently closed single‐stranded transcript. They are a novel class of genomic regulators that are linked to many important development and disease processes and are being pursued as clinical and ...
Qian Wang, Yuanyuan Sun, Qinhua Zhao, Wenhui Wu, Lan Wang, Yuqing Miao, Ping Yuan   +6 more
doaj   +1 more source

CircGSAP regulates the cell cycle of pulmonary microvascular endothelial cells via the miR-942-5p sponge in pulmonary hypertension

Frontiers in Cell and Developmental Biology, 2022
Background We recently demonstrated that circGSAP was diminished in lung tissues from patients with pulmonary arterial hypertension and in hypoxia-induced pulmonary microvascular endothelial cells (PMECs).
Yuanyuan Sun, Yuanyuan Sun, Wenhui Wu, Qinhua Zhao, Rong Jiang, Jinling Li, Lan Wang, Shijin Xia, Mingjie Liu, Sugang Gong, Jinming Liu, Ping Yuan   +11 more
doaj   +1 more source

Differences in disease severity and prognosis of exercise-induced right-to-left shunt between idiopathic pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension patients

Frontiers in Cardiovascular Medicine, 2022
ObjectiveWhether exercise-induced venous-to-systemic shunt (EIS) during cardiopulmonary exercise testing (CPET) has different manifestations or characteristics in idiopathic pulmonary arterial hypertension (IPAH) and chronic thromboembolic pulmonary ...
Shang Wang, Zi-Yan Guo, Xing-Xing Sun, Ping Yuan, Qin-Hua Zhao, Wen-Hui Wu, Hong-Ling Qiu, Ci-Jun Luo, Su-Gang Gong, Hui-Ting Li, Rui Zhang, Jing He, Lan Wang, Jin-Ming Liu, Jian Guo, Rong Jiang   +15 more
doaj   +1 more source

Bronchial Circulation Angiogenesis in the Rat Quantified with SPECT and Micro-CT [PDF]

, 2008
Introduction As pulmonary artery obstruction results in proliferation of the bronchial circulation in a variety of species, we investigated this angiogenic response using single photon emission computed tomography (SPECT) and micro-CT.
Clough, Anne V., Gordon, John B., Haworth, Steven Thomas, Molthen, Robert C., Roerig, David L., Wieholt, Christian   +5 more
core   +2 more sources

Biology and function of pericytes in the vascular microcirculation

Animal Models and Experimental Medicine, 2023
Pericytes are the main cellular components of tiny arteries and capillaries. Studies have found that pericytes can undergo morphological contraction or relaxation under stimulation by cytokines, thus affecting the contraction and relaxation of ...
Yue Wu, Jiaqi Fu, Yuxia Huang, Ruowang Duan, Wentian Zhang, Caihong Wang, Shang Wang, Xiaoyi Hu, Hui Zhao, Lan Wang, Jinming Liu, Guosheng Gao, Ping Yuan   +12 more
doaj   +1 more source

Identification of the shared gene signatures between pulmonary fibrosis and pulmonary hypertension using bioinformatics analysis

Frontiers in Immunology, 2023
Pulmonary fibrosis (PF) and pulmonary hypertension (PH) have common pathophysiological features, such as the significant remodeling of pulmonary parenchyma and vascular wall.
Hui Zhao, Hui Zhao, Lan Wang, Yi Yan, Yi Yan, Qin-Hua Zhao, Jing He, Rong Jiang, Ci-Jun Luo, Hong-Ling Qiu, Yu-Qing Miao, Su-Gang Gong, Ping Yuan, Wen-Hui Wu   +13 more
doaj   +1 more source

Short-term hemodynamic effects of apelin in patients with pulmonary arterial hypertension [PDF]

, 2018
Apelin agonism causes systemic vasodilatation and increased cardiac contractility in humans, and improves pulmonary arterial hypertension (PAH) in animal models.
Alastalo, Apostolopoulou, Ashley, Barnes, Berry, Brame, Cheng, Dai, Falcao-Pires, Grimminger, Japp, Japp, Jing, Kleinz, Lee, Machado, McLaughlin, Morrell, Petkov, Salcedo, Sulica, Tatemoto, Tatemoto, Voswinckel   +23 more
core   +4 more sources

Numerical simulation of blood flow and pressure drop in the pulmonary arterial and venous circulation [PDF]

, 2014
A novel multiscale mathematical and computational model of the pulmonary circulation is presented and used to analyse both arterial and venous pressure and flow. This work is a major advance over previous studies by Olufsen et al. (Ann Biomed Eng 28:1281–
AC Burton, AJ Peacock, AJ Peacock, AR Pries, BI Levy, BN Steele, CA Figueroa, CA Taylor, Charles S. Peskin, Christopher Sainsbury, CW Li, D Mukerjee, DJ Patel, DJ Patel, E Hachulla, E Peskin, EH Hollander, EO Attinger, ER Weibel, FN Vosse van de, FY Zhuang, FY Zhuang, G Simonneau, Gareth D. A. Vaughan, GH Fonseca, GS Krenz, HBM Uylings, IE Vignon-Clementel, J Alastruey, J Fullana, JC Greenfield, JE Hall, JT Reeves, JW Lankhaar, K Azer, KS Matthys, L Formaggia, M. Umar Qureshi, Martin Johnson, Mette S. Olufsen, MS Olufsen, MS Olufsen, MS Olufsen, MS Pollanen, N Suwa, N Xiao, N. A. Hill, O Sitbon, P Dartevelle, P Herve, P Reymond, PH Bovendeerd, PJ Barnes, R Kato, RB Clipp, RB Clipp, RF Machado, RJ Barst, RL Evans, RM Tuder, RT Yen, S Singhal, SJ Sherwin, V Castelain, W Cousins, W Huang, WM Thurlbeck, WR Milnor, WW Nichols, Y Gao, Y Huo, Y Kawahira, YC Fung, YH Kim   +73 more
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Pulmonary vasospasm in systemic sclerosis: noninvasive techniques for detection [PDF]

, 2014
In a subgroup of patients with systemic sclerosis (SSc), vasospasm affecting the pulmonary circulation may contribute to worsening respiratory symptoms, including dyspnea.
Giannarou, S, Hansell, DM, Keir, GJ, MacDonald, P, Nair, A, Oldershaw, P, Wells, AU, Wort, SJ, Yang, G-Z   +8 more
core   +1 more source