Results 11 to 20 of about 2,151,759 (386)

Parameter Inference in the Pulmonary Circulation of Mice [PDF]

open access: green, 2017
This study focuses on parameter inference in a pulmonary blood cir- culation model for mice. It utilises a fluid dynamics network model that takes selected parameter values and aims to mimic features of the pulmonary haemody- namics under normal ...
L. Mihaela Păun   +6 more
openalex   +2 more sources

CircGSAP alleviates pulmonary microvascular endothelial cells dysfunction in pulmonary hypertension via regulating miR-27a-3p/BMPR2 axis

open access: yesRespiratory Research, 2022
Background Our previous study showed that circular RNA-gamma-secretase-activating protein (circGSAP) was down-regulated in pulmonary microvascular endothelial cells (PMECs) in response to hypoxia, and regulated the cell cycle of PMECs via miR-942-5p ...
Yuanyuan Sun   +11 more
doaj   +1 more source

Numerical simulation of blood flow and pressure drop in the pulmonary arterial and venous circulation [PDF]

open access: yesBiomechanics and Modeling in Mechanobiology, 2014
A novel multiscale mathematical and computational model of the pulmonary circulation is presented and used to analyse both arterial and venous pressure and flow. This work is a major advance over previous studies by Olufsen et al. (Ann Biomed Eng 28:1281–
M. U. Qureshi   +7 more
semanticscholar   +3 more sources

Peak oxygen uptake is a strong prognostic predictor for pulmonary hypertension due to left heart disease

open access: yesBMC Cardiovascular Disorders, 2022
Background Pulmonary hypertension in left heart disease (PH-LHD), which includes combined post- and precapillary PH (Cpc-PH) and isolated postcapillary PH (Ipc-PH), differs significantly in prognosis.
Xiu-Jun Zhong   +13 more
doaj   +1 more source

Efficacy and safety of switching from bosentan or ambrisentan to macitentan in pulmonary arterial hypertension: A systematic review and meta-analysis

open access: yesFrontiers in Cardiovascular Medicine, 2022
BackgroundThere is little evidence of the effectiveness of switching from the endothelin receptor antagonists (ERAs) bosentan and ambrisentan to a novel ERA, macitentan, in patients with pulmonary arterial hypertension (PAH).
Jie Li   +14 more
doaj   +1 more source

A novel pulmonary circulation imaging using dynamic digital radiography for chronic thromboembolic pulmonary hypertension

open access: yesEuropean Heart Journal, 2020
A 46-year-old man with chronic thromboembolic pulmonary hypertension (CTEPH) was referred to our hospital to undergo pulmonary endarterectomy (PEA). Tc-99m MAA lung perfusion scintigraphy showed multiple perfusion defects in the bilateral lung field ...
Y. Yamasaki   +3 more
semanticscholar   +1 more source

Role of miR‐21‐5p/FilGAP axis in estradiol alleviating the progression of monocrotaline‐induced pulmonary hypertension

open access: yesAnimal Models and Experimental Medicine, 2022
Background Aberrant expression of microRNAs (miRNAs) has been associated with the pathogenesis of pulmonary hypertension (PH). It is, however, not clear whether miRNAs are involved in estrogen rescue of PH. Methods Fresh plasma samples were prepared from
Xiaoyi Hu   +8 more
doaj   +1 more source

Liver dysfunction in idiopathic pulmonary arterial hypertension: prevalence, characteristics and prognostic significance, a retrospective cohort study in China

open access: yesBMJ Open, 2021
Objectives The aim was to elucidate the relationship between liver function and idiopathic pulmonary arterial hypertension (IPAH).Design and setting Retrospective, longitudinal study in urban tertiary care centre in Shanghai, China.Participants 407 IPAH ...
Rui Zhang   +12 more
doaj   +1 more source

Echocardiographic Prognosis Relevance of Attenuated Right Heart Remodeling in Idiopathic Pulmonary Arterial Hypertension

open access: yesFrontiers in Cardiovascular Medicine, 2021
Background: Right ventricular (RV) function is a great determination of the fate in patients with pulmonary arterial hypertension (PAH). Monitoring RV structure back to normal or improvement should be useful for evaluation of RV function.
Qin-Hua Zhao   +11 more
doaj   +1 more source

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