Results 61 to 70 of about 2,069,003 (398)

Role of Kv7 channels in responses of the pulmonary circulation to hypoxia

American Journal of Physiology - Lung cellular and Molecular Physiology, 2014
Hypoxic pulmonary vasoconstriction (HPV) is a beneficial mechanism that diverts blood from hypoxic alveoli to better ventilated areas of the lung, but breathing hypoxic air causes the pulmonary circulation to become hypertensive.
Vojtěch Šedivý, Shreena Joshi, Youssef Ghaly, R. Mizera, M. Žaloudíková, S. Brennan, J. Novotná, J. Herget, A. Gurney   +8 more
semanticscholar   +1 more source

Pressor effects of circulating endothelin are limited by its removal in the pulmonary circulation and by the release of prostacyclin and endothelium-derived relaxing factor.

Proceedings of the National Academy of Sciences of the United States of America, 1988
Endothelin releases prostacyclin and thromboxane A2 from guinea pig or rat isolated lungs and endothelium-derived relaxing factor in the perfused mesentery of the rat.
G. Nucci, R. Thomas, P. D'Orléans-Juste, E. Antunes, C. Walder, T. Warner, J. Vane   +6 more
semanticscholar   +1 more source

Transition from Ambrisentan to Bosentan in Pulmonary Arterial Hypertension: A Single-Center Prospective Study

Canadian Respiratory Journal, 2018
Background and objective: Two endothelin receptor antagonists (ETRAs), bosentan and ambrisentan, are approved for patients with pulmonary arterial hypertension (PAH).
Su-Gang Gong, Lan Wang, Bigyan Pudasaini, Ping Yuan, Rong Jiang, Qin-Hua Zhao, Jing He, Rui Zhang, Wen-hui Wu, Jin-Ming Liu, Cai-cun Zhou   +10 more
doaj   +1 more source

Arterial and venous thromboembolism risk associated with blood eosinophils: A systematic review and meta‐analysis

Animal Models and Experimental Medicine, 2022
The association between blood eosinophil (EOS) counts and arterial/venous thrombosis is unclear. We aim to explore whether EOS count is a risk factor for thrombosis.
Wei‐Jie Xu, Shang Wang, Ping Yuan, Lan Wang, Jun‐Xia Huang, Rong Jiang   +5 more
doaj   +1 more source

Decreased time constant of the pulmonary circulation in chronic thromboembolic pulmonary hypertension.

American Journal of Physiology. Heart and Circulatory Physiology, 2013
This study analyzed the relationship between pulmonary vascular resistance (PVR) and pulmonary arterial compliance (Ca) in patients with idiopathic pulmonary arterial hypertension (IPAH) and proximal chronic thromboembolic pulmonary hypertension (CTEPH).
R. M. MacKenzie Ross, M. Toshner, E. Soon, R. Naeije, J. Pepke-Zaba   +4 more
semanticscholar   +1 more source

Regulation of the pulmonary circulation [PDF]

Heart, 1971
Factors regulating pressure and flow in the lungs are reviewed with particular emphasis on their role in regulating blood flow velocity and distribution within the lung capillaries. The behaviour of the pulmonary arterial, system, alveolar capillaries, and pulmonary venous system are considered individually.
openaire   +3 more sources

Aminorex and the pulmonary circulation [PDF]

Thorax, 1971
Aminorex (2-amino-5-phenyl-2-oxazoline) is an appetite-suppressing drug which was available in Switzerland from November 1965 to October 1968. In 1967 a sudden 20-fold increase in the incidence of primary pulmonary hypertension was observed in a Swiss medical clinic.
J. M. Kay, Paul Smith, Donald Heath
openaire   +3 more sources

An algorithm to identify cases of pulmonary arterial hypertension from the electronic medical record

Respiratory Research, 2022
Background Study of pulmonary arterial hypertension (PAH) in claims-based (CB) cohorts may facilitate understanding of disease epidemiology, however previous CB algorithms to identify PAH have had limited test characteristics.
Kyle P. Schuler, Anna R. Hemnes, Jeffrey Annis, Eric Farber-Eger, Brandon D. Lowery, Stephen J. Halliday, Evan L. Brittain   +6 more
doaj   +1 more source

A Preliminary Study on the Relationship Between High-Resolution Computed Tomography and Pulmonary Function in People at Risk of Developing Chronic Obstructive Pulmonary Disease

Frontiers in Medicine, 2022
ObjectivesPatients with chronic obstructive pulmonary disease (COPD) have high morbidity and mortality, the opportunity to carry out a thoracic high-resolution CT (HRCT) scan may increase the possibility to identify the group at risk of disease.
Rui Lv, Rui Lv, Mengyao Xie, Huaqian Jin, Pingping Shu, Mingli Ouyang, Yanmao Wang, Dan Yao, Lehe Yang, Xiaoying Huang, Yiran Wang   +10 more
doaj   +1 more source

Optimal fenestration of the Fontan circulation [PDF]

arXiv, 2022
In this paper, we develop a pulsatile compartmental model of the Fontan circulation and use it to explore the effects of a fenestration added to this physiology. A fenestration is a shunt between the systemic and pulmonary veins that is added either at the time of Fontan conversion or at a later time for the treatment of complications.
arxiv