Results 61 to 70 of about 2,151,759 (386)

An algorithm to identify cases of pulmonary arterial hypertension from the electronic medical record

Respiratory Research, 2022
Background Study of pulmonary arterial hypertension (PAH) in claims-based (CB) cohorts may facilitate understanding of disease epidemiology, however previous CB algorithms to identify PAH have had limited test characteristics.
Kyle P. Schuler, Anna R. Hemnes, Jeffrey Annis, Eric Farber-Eger, Brandon D. Lowery, Stephen J. Halliday, Evan L. Brittain   +6 more
doaj   +1 more source

A Preliminary Study on the Relationship Between High-Resolution Computed Tomography and Pulmonary Function in People at Risk of Developing Chronic Obstructive Pulmonary Disease

Frontiers in Medicine, 2022
ObjectivesPatients with chronic obstructive pulmonary disease (COPD) have high morbidity and mortality, the opportunity to carry out a thoracic high-resolution CT (HRCT) scan may increase the possibility to identify the group at risk of disease.
Rui Lv, Rui Lv, Mengyao Xie, Huaqian Jin, Pingping Shu, Mingli Ouyang, Yanmao Wang, Dan Yao, Lehe Yang, Xiaoying Huang, Yiran Wang   +10 more
doaj   +1 more source

Pathophysiology and new advances in pulmonary hypertension

BMJ Medicine, 2023
Pulmonary hypertension is a progressive and often fatal cardiopulmonary condition characterised by increased pulmonary arterial pressure, structural changes in the pulmonary circulation, and the formation of vaso-occlusive lesions.
S. Bousseau, R. Sobrano Fais, S. Gu, A. Frump, T. Lahm   +4 more
semanticscholar   +1 more source

Cerebrospinal Fluid Liquid Biopsy Enables Targeted Therapy Without Tissue Diagnosis in Pediatric Low‐Grade Gliomas With BRAF V600E Mutation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT We present two pediatric cases of pediatric low‐grade gliomas (PLGG) with BRAF V600E mutations diagnosed and monitored using cerebrospinal fluid (CSF) liquid biopsy analyzed via digital droplet PCR (ddPCR), without tissue biopsy. Both patients were treated with dabrafenib and trametinib and monitored through clinical assessments, magnetic ...
Hannah Sultan, Damien Faury, Alexander G. Weil, Harrison J. Westwick, Nada Jabado, Sébastien Perreault   +5 more
wiley   +1 more source

Phenotypic Analysis of Pulmonary Hypertension Associated With Low Diffusion Capacity and Preserved Lung Function

Pulmonary Circulation
Severe diffusion impairment in pulmonary arterial hypertension (PAH), particularly in idiopathic PAH (IPAH), has garnered considerable attention. However, comprehensive data on low diffusion capacity of the lungs for carbon monoxide (DLCO) with preserved
Qin‐Hua Zhao, Rui Zhang, Shao‐Fei Liu, Ci‐Jun Luo, Hong‐Ling Qiu, Wen‐Hui Wu, Hui‐Ting Li, Jing He, Ping Yuan, Jian Xu, Jin‐Ming Liu, Su‐Gang Gong, Lan Wang   +12 more
doaj   +1 more source

Novel signaling pathways in pulmonary arterial hypertension (2015 Grover Conference Series) [PDF]

, 2016
The proliferative endothelial and smooth muscle cell phenotype, inflammation, and pulmonary vascular remodeling are prominent features of pulmonary arterial hypertension (PAH).
Awad, Keytam S., de Jesus Perez, Vinicio, MacLean, Margaret, West, James D.   +3 more
core   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

CircALMS1 Alleviates Pulmonary Microvascular Endothelial Cell Dysfunction in Pulmonary Hypertension

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Circular RNAs can serve as regulators influencing the development of pulmonary hypertension (PH). However, their function in pulmonary vascular intimal injury remains undefined.
Xiaoyi Hu, Yuanyuan Sun, Shang Wang, Hui Zhao, Yaqin Wei, Jiaqi Fu, Yuxia Huang, Wenhui Wu, Jinling Li, Jinming Liu, Sugang Gong, Qinhua Zhao, Lan Wang, Rong Jiang, Xiao Song, Ping Yuan   +15 more
doaj   +1 more source

Arterial and venous thromboembolism risk associated with blood eosinophils: A systematic review and meta‐analysis

Animal Models and Experimental Medicine, 2022
The association between blood eosinophil (EOS) counts and arterial/venous thrombosis is unclear. We aim to explore whether EOS count is a risk factor for thrombosis.
Wei‐Jie Xu, Shang Wang, Ping Yuan, Lan Wang, Jun‐Xia Huang, Rong Jiang   +5 more
doaj   +1 more source

MiR-122-5p as a potential regulator of pulmonary vascular wall cell in idiopathic pulmonary arterial hypertension

Heliyon, 2023
MicroRNAs (miRNAs) are versatile regulators of pulmonary arterial remodeling in idiopathic pulmonary arterial hypertension (IPAH). We herein aimed to characterize miRNAs in peripheral blood mononuclear cell (PBMC) and plasma exosomes, and investigate ...
Hui Zhao, Ruowang Duan, Qian Wang, Xiaoyi Hu, Qinhua Zhao, Wenhui Wu, Rong Jiang, Sugang Gong, Lan Wang, Jinming Liu, Jie Deng, Huazheng Liang, Yuqing Miao, Ping Yuan   +13 more
doaj   +1 more source