Results 111 to 120 of about 117,017 (302)
The FEBS Journal, EarlyView.A major complication of organ transplantation is primary graft dysfunction, which represents the leading cause of early post‐transplantation morbidity and mortality. Pre‐operative depletion of neutrophil serine proteases in circulating neutrophils by pretreatment with a cathepsin C inhibitor in recipients could prevent early post‐operative ...
Sevil Korkmaz‐Icöz +6 more
wiley +1 more source
LUNG FUNCTION STUDIES. V. RESPIRATORY DEAD SPACE IN OLD AGE AND IN PULMONARY EMPHYSEMA 1 [PDF]
, 1950 Ward S. Fowler
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Age-related changes in the respiratory system [PDF]
, 1999 This article summarises the main structural and physiological changes which take place in the lung from young adulthood to senescence. An understanding of these changes helps the clinician to correctly interpret some results of radiology and pulmonary ...
Ebejer, Martin J., Lesauskaite, Vita
core
Impact of N‐linked glycans on the dual short fibulin/LTBP‐4 axes regulating elastogenesis
The FEBS Journal, EarlyView.Elastic fiber assembly is orchestrated by multiple glycoproteins. We delineate the molecular basis of two key axes involved in elastic fiber formation—LTBP‐4L/fibulin‐4 and LTBP‐4S/fibulin‐5. We show that N‐linked glycans on these glycoproteins regulate their interactions and conformations, both of which are critical aspects in elastic fiber formation.
Valentin Nelea +8 more
wiley +1 more source
Stem Cell Research & Therapy, 2019 Introduction Pulmonary emphysema is a major component of chronic obstructive pulmonary disease (COPD). Emphysema progression attributed not only to alveolar structure loss and pulmonary regeneration impairment, but also to excessive inflammatory response,
Ying-Wei Lan +7 more
doaj +1 more source
DISTRIBUTION OF RESPIRATORY GASES IN A CLOSED BREATHING CIRCUIT. II. PULMONARY FIBROSIS AND EMPHYSEMA [PDF]
, 1937 A. Cournand +2 more
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Tissue Resident Memory Cells: Friend or Foe?
Immunology, EarlyView.Tissue‐resident memory T cells (TRM cells) are specialised immune cells in barrier tissues like the lungs, skin and gut, providing rapid host defence and tumour surveillance. Their retention and differentiation are regulated by molecules such as CD69, CD103 and TGF‐β. Dysregulation of TRM cells can lead to chronic activation, driving conditions such as
Chidimma F. Chude +2 more
wiley +1 more source
Respiratory Research, 2019 Background Elastin breakdown and the resultant loss of lung elastic recoil is a hallmark of pulmonary emphysema in susceptible individuals as a consequence of tobacco smoke exposure. Systemic alterations to the synthesis and degradation of elastin may be
Michael E. O’Brien +12 more
doaj +1 more source
Journal of the European Academy of Dermatology and Venereology, EarlyView.This cohort study of 1793 atopic dermatitis patients (aged ≥ 12) found higher infection rates with Janus kinase inhibitor treatment compared to biologic treatment, particularly for herpes infections, with a history of viral or fungal skin infection as a risk factor associated with infection.
Lian F. van der Gang +22 more
wiley +1 more source