Results 41 to 50 of about 63,952 (206)

Spirometric assessment of emphysema presence and severity as measured by quantitative CT and CT-based radiomics in COPD

Respiratory Research, 2019
Background The mechanisms underlying airflow obstruction in COPD cannot be distinguished by standard spirometry. We ascertain whether mathematical modeling of airway biomechanical properties, as assessed from spirometry, could provide estimates of ...
Mariaelena Occhipinti, Matteo Paoletti, Brian J. Bartholmai, Srinivasan Rajagopalan, Ronald A. Karwoski, Cosimo Nardi, Riccardo Inchingolo, Anna R. Larici, Gianna Camiciottoli, Federico Lavorini, Stefano Colagrande, Vito Brusasco, Massimo Pistolesi   +12 more
doaj   +1 more source

Improvement of pulmonary arterial compliance by pulmonary vasodilator in pulmonary hypertension from combined pulmonary fibrosis and emphysema

Respiratory Medicine Case Reports, 2019
Combined pulmonary fibrosis and emphysema (CPFE) is a common but under-recognized syndrome characterized with distinct profiles of both pulmonary fibrosis and emphysema.
Kei Kusaka, Yoshiteru Morio, Yuya Kimura, Keita Takeda, Masahiro Kawashima, Kimihiko Masuda, Hirotoshi Matsui   +6 more
doaj  

Characterization of a spontaneous mouse model of mild, accelerated aging via ECM degradation in emphysematous lungs

Scientific Reports, 2023
Emphysema limits airflow and causes irreversible progression of chronic obstructive pulmonary disease (COPD). Strain differences must be considered when selecting mouse models of COPD, owing to disease complexity.
Ryosuke Tanino, Yukari Tsubata, Takamasa Hotta, Tamio Okimoto, Yoshihiro Amano, Mayumi Takechi, Tetsuya Tanaka, Tomomi Akita, Mamiko Nagase, Chikamasa Yamashita, Koichiro Wada, Takeshi Isobe   +11 more
doaj   +1 more source

Severe pulmonary hypertension due to combined pulmonary fibrosis and emphysema: another cause of death among smokers

Autopsy and Case Reports, 2017
In 2005, the combined pulmonary fibrosis and emphysema (CPFE) was first defined as a distinct entity, which comprised centrilobular or paraseptal emphysema in the upper pulmonary lobes, and fibrosis in the lower lobes accompanied by reduced diffused ...
André Carramenha de Góes Hirano, Eduardo Pelegrineti Targueta, Fernando Peixoto Ferraz de Campos, João Augusto dos Santos Martines, Dafne Andrade, Silvana Maria Lovisolo, Aloisio Felipe-Silva   +6 more
doaj   +1 more source

Critical role of tumor necrosis factor receptor 1 in the pathogenesis of pulmonary emphysema in mice

International Journal of COPD, 2016
Masaki Fujita,1 Hiroshi Ouchi,2 Satoshi Ikegame,2 Eiji Harada,2 Takemasa Matsumoto,1 Junji Uchino,1 Yoichi Nakanishi,2 Kentaro Watanabe1 1Department of Respiratory Medicine, Faculty of Medicine, Fukuoka University, 2Research Institute for Diseases of ...
Fujita M, Ouchi H, Ikegame S, Harada E, Matsumoto T, Uchino J, Nakanishi Y, Watanabe K   +7 more
doaj  

A case report of subconjunctival emphysema as a rare complication of pulmonary resections

Journal of Minimal Access Surgery
Lung volume reduction surgery (LVRS) is performed to the selected patients with lung emphysema who have higher residual volume, restricted pulmonary functions and limited diaphragmatic movement. Post-operative prolonged air leak is not uncommon following
Ismail Sarbay, Akif Turna
doaj   +1 more source

Phase I clinical trial of cell therapy in patients with advanced chronic obstructive pulmonary disease: follow-up of up to 3 years

Revista Brasileira de Hematologia e Hemoterapia, 2013
BACKGROUND Chronic obstructive pulmonary disease is a major inflammatory disease of the airways and an enormous therapeutic challenge. Within the spectrum of chronic obstructive pulmonary disease, pulmonary emphysema is characterized by the destruction ...
Talita Stessuk, Milton Artur Ruiz, Oswaldo Tadeu Greco, Aldemir Bilaqui, Maria Jose de Oliveira Ribeiro-Paes, Joao Tadeu Ribeiro-Paes   +5 more
doaj   +1 more source

Quantitative severity of pulmonary emphysema as a prognostic factor for recurrence in patients with surgically resected non‐small cell lung cancer

Thoracic Cancer, 2019
Background Pulmonary emphysema is a major component of chronic obstructive pulmonary disease and lung cancer. However the prognostic significance of quantitative emphysema severity in patients with lung cancer is unclear.
Seung Jun Lee, Jung Wan Yoo, Sunmi Ju, Yu Ji Cho, Jong Duk Kim, Sung Hwan Kim, In‐Seok Jang, Bae Kwon Jeong, Gyeong‐Won Lee, Yi Yeong Jeong, Ho Cheol Kim, Kyungsoo Bae, Kyung Nyeo Jeon, Jong Deog Lee   +13 more
doaj   +1 more source

The impact of emphysema in pulmonary fibrosis [PDF]

European Respiratory Review, 2013
Several groups have described a syndrome in which idiopathic pulmonary fibrosis (IPF) coexists with pulmonary emphysema. This comes as no surprise since both diseases are associated with a history of exposure to cigarette smoke. The syndrome of combined pulmonary fibrosis and emphysema (CPFE) is characterised by upper lobe emphysema and lower lobe ...
openaire   +5 more sources

Predicting clinical outcome with phenotypic clusters using quantitative CT fibrosis and emphysema features in patients with idiopathic pulmonary fibrosis.

PLoS ONE, 2019
BackgroundThe clinical course of IPF varies. This study sought to identify phenotyping with quantitative computed tomography (CT) fibrosis and emphysema features using a cluster analysis and to assess prognostic impact among identified clusters in ...
So Hyeon Bak, Hye Yun Park, Jin Hyun Nam, Ho Yun Lee, Jeong Hyun Lee, Insuk Sohn, Man Pyo Chung   +6 more
doaj   +1 more source