Results 41 to 50 of about 64,581 (287)

Clinical progress note: Pertussis

Journal of Hospital Medicine, EarlyView.
Abstract Pertussis, commonly known as whooping cough, is a vaccine‐preventable respiratory disease with rising incidence due to declining vaccination rates and waning immunity. The most severe disease course is seen in unvaccinated or incompletely vaccinated infants less than 2 months of age, accounting for the largest burden of hospitalization and ...
Samantha Hanna, Nicole Samies
wiley   +1 more source

A formula for predicting emphysema extent in combined idiopathic pulmonary fibrosis and emphysema

Respiratory Research
Background No single pulmonary function test captures the functional effect of emphysema in idiopathic pulmonary fibrosis (IPF). Without experienced radiologists, other methods are needed to determine emphysema extent. Here, we report the development and
Athol U. Wells, Joseph Jacob, Nicola Sverzellati, Gary Cross, Joseph Barnett, Angelo De Lauretis, Katerina Antoniou, Derek Weycker, Mark Atwood, Klaus-Uwe Kirchgaessler, Vincent Cottin   +10 more
doaj   +1 more source

Combined pulmonary fibrosis and emphysema syndrome: a radiologic perspective

Monaldi Archives for Chest Disease, 2015
Chronic obstructive pulmonary disease (that includes emphysema) results in significant morbidity and mortality worldwide. Idiopathic pulmonary fibrosis (IPF) is also a chronic and progressive parenchymal lung disease with an average survival of less than
I.B. Oliva, F. Cortopassi, C.L. Rochester, A.N. Rubinowitz   +3 more
doaj   +1 more source

Functional Pulmonary Imaging

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT The aging of the world population gave rise to an increased prevalence of many lung diseases, with chronic obstructive pulmonary disease now ranking as the third‐leading cause of death according to the World Health Organization. To diagnose lung disease, a thorough assessment of lung function is essential since it may reveal unique signatures ...
Agilo L. Kern, Filip Klimeš, Andreas Voskrebenzev, Hoen‐Oh Shin, Jens Vogel‐Claussen   +4 more
wiley   +1 more source

Magnetic Resonance Imaging in the Clinical Evaluation of Lung Disorders: Current Status and Future Prospects

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT The low proton density and high signal decay rate of pulmonary tissue have previously hampered the application of magnetic resonance imaging (MRI) in the clinical evaluation of lung disorders. With the continuing technical advances in scanners, coils, pulse sequences, and image postprocessing, pulmonary MRI can provide structural and ...
Linyu Wu, Chen Gao, Ting Wu, Ning Kong, Ziwei Zhang, Jie Li, Li Fan, Maosheng Xu   +7 more
wiley   +1 more source

Eosinophils promote pulmonary matrix destruction and emphysema via Cathepsin L

Signal Transduction and Targeted Therapy, 2023
Patients with chronic obstructive pulmonary disease (COPD) who exhibit elevated blood eosinophil levels often experience worsened lung function and more severe emphysema.
Xia Xu, Tao Yu, Lingling Dong, Rainer Glauben, Siyuan Wu, Ronghua Huang, Shiwei Qumu, Chenli Chang, Jing Guo, Lin Pan, Ting Yang, Xin Lin, Ke Huang, Zhihua Chen, Chen Wang   +14 more
doaj   +1 more source

Pediatric Sharp Foreign Body Aspiration: Revealing Unexpected Risk Factors

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Characterize the demographic and clinical features of pediatric sharp foreign body aspiration (FBA). Study Design Twenty‐four‐year retrospective chart review. Setting Four tertiary‐care centers across four Canadian provinces. Methods A retrospective chart review was conducted on pediatric patients who underwent rigid bronchoscopy for
Alicia Belaiche, Trevor A. Lewis, Jakob Pugi, Mariya Bogatchenko, Liane B. Johnson, Trina C. Rosaasen, Lily H. P. Nguyen   +6 more
wiley   +1 more source

Age‐Dependent Correlation of Pulmonary Function Impairment and Aortic Arch Stiffness in Mice

Pediatric Discovery, EarlyView.
This study examined the relationship between aortic arch stiffness and lung function in aging mice. Multiple linear regression modeling showed moderate to strong correlations between the rise in aortic arch stiffness and changes in lung function as the mice progressively aged.
Ayman Isbatan, Samuel M. Lee, Ali Imran Sarwar, Yuxing Yuan, Sunny Chen, Maricela Castellon, Dan A. Marian, Richard D. Minshall, Jie Tian, Irena Levitan, Jiwang Chen   +10 more
wiley   +1 more source

A Combined Model‐Based Meta‐Analysis of Aggregated and Individual FEV1 Data From Randomized COPD Trials

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Model‐based meta‐analysis allows integration of aggregated‐level data (AD) from different clinical trials in one model to assess population efficacy/safety. However, AD is limited in individual‐level information, while individual‐patient‐level data (IPD) are hard to obtain. Combined modeling may take advantage of both sources.
Liang Yang, Carolina Llanos‐Paez, Shuying Yang, Claire Ambery, Alienor Berges, Maria C. Kjellsson, Mats O. Karlsson   +6 more
wiley   +1 more source

Pulmonary Vascular Volume by Quantitative CT in Dyspneic Smokers with Minor Emphysema

COPD, 2023
Reduced lung diffusing capacity for carbon monoxide (DLCO) at rest and increased ventilation (⩒E)-carbon dioxide output (⩒CO2) during exercise are frequent findings in dyspneic smokers with largely preserved FEV1.
Amany F. Elbehairy, Sandra G. Vincent, Devin B. Phillips, Matthew D. James, Jenna Veugen, Grace Parraga, Denis E. O’Donnell, J. Alberto Neder   +7 more
doaj   +1 more source