Tackling MARCKS-PIP3 circuit attenuates fibroblast activation and fibrosis progression. [PDF]
, 2019 Targeting activated fibroblasts, including myofibroblast differentiation, has emerged as a key therapeutic strategy in patients with idiopathic pulmonary fibrosis (IPF).
Chen, Ching-Hsien +7 more
core +2 more sources
Coagulation and anticoagulation in idiopathic pulmonary fibrosis [PDF]
, 2015 Idiopathic pulmonary fibrosis (IPF) is an incurable, progressive interstitial lung disease with a prognosis that is worse than that of many cancers. Epidemiological studies have demonstrated a link between IPF and thrombotic vascular events.
Crooks, Michael G., Hart, Simon P.
core +3 more sources
Relationship between pulmonary exacerbations and daily physical activity in adults with cystic fibrosis [PDF]
, 2015 The aim of this study was to examine the relationship between pulmonary exacerbations and physical activity (PA) in adults with cystic fibrosis (CF)
Banya, Winston +7 more
core +2 more sources
Informal caregivers experience of supplemental oxygen in pulmonary fibrosis
Health and Quality of Life Outcomes, 2017 Background Patients prescribed supplemental oxygen (O2) therapy face challenges as they adjust to being constantly “tethered” to an oxygen delivery device.
Bridget A. Graney +8 more
doaj +1 more source
Comorbid Conditions in Idiopathic Pulmonary Fibrosis: Recognition and Management. [PDF]
, 2017 Idiopathic pulmonary fibrosis (IPF), a fibrosing interstitial pneumonia of unknown etiology, primarily affects older adults and leads to a progressive decline in lung function and quality of life.
Collard, Harold R, Oldham, Justin M
core +2 more sources
Fibrosis-Net: A Tailored Deep Convolutional Neural Network Design for Prediction of Pulmonary Fibrosis Progression from Chest CT Images [PDF]
arXiv, 2021 Pulmonary fibrosis is a devastating chronic lung disease that causes irreparable lung tissue scarring and damage, resulting in progressive loss in lung capacity and has no known cure. A critical step in the treatment and management of pulmonary fibrosis is the assessment of lung function decline, with computed tomography (CT) imaging being a ...
arxiv
Semi-Supervised Segmentation of Radiation-Induced Pulmonary Fibrosis from Lung CT Scans with Multi-Scale Guided Dense Attention [PDF]
, 2021 Computed Tomography (CT) plays an important role in monitoring radiation-induced Pulmonary Fibrosis (PF), where accurate segmentation of the PF lesions is highly desired for diagnosis and treatment follow-up. However, the task is challenged by ambiguous boundary, irregular shape, various position and size of the lesions, as well as the difficulty in ...
arxiv +1 more source
Early life growth patterns persist for 12 years and impact pulmonary outcomes in cystic fibrosis [PDF]
, 2018 BACKGROUND: In children with cystic fibrosis (CF), recovery from growth faltering within 2 years of diagnosis (Responders) is associated with better growth and less lung disease at age 6 years.
Farrell, Philip M. +3 more
core +1 more source
Cough suppression and HRQoL in adult people with cystic fibrosis: an unexplored correlation
Health and Quality of Life Outcomes, 2022 Background Cough suppression assessed by embarrassment about coughing has been shown in adolescents with cystic fibrosis (CF) and negatively affects health-related quality of life (HRQoL) and clinical indicators of disease severity in adolescent females.
Ute Niehammer +7 more
doaj +1 more source
Medicines, 2021 Current FDA-approved antifibrotic treatments for Idiopathic Pulmonary Fibrosis slow down disease progression but have little impact on symptoms or quality of life in patients.
Neha Shah
doaj +1 more source