Results 71 to 80 of about 1,677,383 (218)

Assessing the impact of triiodothyronine treatment on the lung microbiome of mice with pulmonary fibrosis

BMC Pulmonary Medicine
Background Idiopathic pulmonary fibrosis (IPF), an interstitial lung disease, is characterized by the exacerbation of progressive pulmonary fibrosis (PF). IPF primarily affects older individuals and can lead to respiratory failure.
Xiaoshu Guo, Kai Xu, Qiwen Wang, Zongyuan Han, Guoying Yu   +4 more
doaj   +1 more source

GSR Deficiency Exacerbates Oxidative Stress and Promotes Pulmonary Fibrosis

Biomolecules
Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal lung disorder characterized by excessive scarring of lung tissue, predominantly affecting middle-aged and elderly populations.
Wenyu Zhao, Hehe Cao, Wenbo Xu, Yudi Duan, Yulong Gan, Shuang Huang, Ying Cao, Siqi Long, Yingying Zhang, Guoying Yu, Lan Wang   +10 more
doaj   +1 more source

Case Series: Hyperbilirubinemia under elexacaftor/tezacaftor/ivacaftor in the presence of Gilbert’s syndrome

BMC Pulmonary Medicine
Liver-related side effects are a known complication of treatment with elexacaftor/tezacaftor/ivacaftor (ETI) for cystic fibrosis (CF). Gilbert’s syndrome is caused by a genetic mutation that reduces activity of the enzyme UDP glucuronosyltransferase 1 ...
Julia Weitzel, Matthias Welsner, Christian Taube, Manfred Ballmann, Sivagurunathan Sutharsan   +4 more
doaj   +1 more source

Validating the Data Completeness and Accuracy of the Canadian Cystic Fibrosis Registry

Canadian Respiratory Journal
Conclusion: Our validation of the CCFR demonstrated high accuracy for clinical and demographic variables used in clinical research.
Ranjani Somayaji, Stephanie Y. Cheng, Noma Abdulrahem, Sanja Stanojevic, Paul Eckford, Bradley S. Quon, Elizabeth Cromwell, Albert Faro, Christopher H. Goss, Anne L. Stephenson   +9 more
doaj   +1 more source

Telomere length and immunosuppression in non-idiopathic pulmonary fibrosis interstitial lung disease [PDF]

, 2023
David Zhang, Ayodeji Adegunsoye, Justin M. Oldham, Julia Kozlitina, Nicole Garcia, Maria Poonawalla, R. Strykowski, A. Linderholm, Brett Ley, Shwu‐Fan Ma, Imre Noth, Mary E. Strek, Paul J. Wolters, Christine Kim Garcia, Chad A. Newton   +14 more
openalex   +1 more source

CAMKK2 restored mitochondrial dynamics homeostasis to alleviate pulmonary fibrosis via AMPK/PGC-1α signaling pathway in lung fibroblasts

Molecular Medicine
Background Idiopathic pulmonary fibrosis (IPF) is a fatal lung disease characterized by aberrant fibroblast activation and extracellular matrix deposition. Emerging evidence implicates mitochondrial dysfunction in IPF pathogenesis.
Yanlin Zhou, Yuqi Wang, Mengyuan Wang, Bin Li, Kai Xu, Xiaoyue Pan, Zhongzheng Li, Qiwen Wang, Wanyu He, Jiaojiao Pang, Yingchun Guo, Yuqing Zhang, Koji Sakamoto, Juntang Yang, Lan Wang, Guoying Yu   +15 more
doaj   +1 more source

Idiopathic pulmonary fibrosis: pathogenesis and management

Respiratory Research, 2018
BackgroundIdiopathic pulmonary fibrosis (IPF) is a chronic, progressive disease characterized by the aberrant accumulation of fibrotic tissue in the lungs parenchyma, associated with significant morbidity and poor prognosis.
G. Sgalla, B. Iovene, M. Calvello, Margherita Ori, F. Varone, L. Richeldi   +5 more
semanticscholar   +1 more source

Contribution of multiple inert gas elimination technique to pulmonary medicine. 2. Chronic pulmonary diseases: chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis. [PDF]

, 1994
Àlvar Agustí, Joan Albert Barberà
openalex   +1 more source

Triiodothyronine acts on DAO to regulate pulmonary fibrosis progression by facilitating cell senescence through the p53/p21 signaling pathway

Frontiers in Pharmacology
BackgroundIdiopathic pulmonary fibrosis (IPF) is the result of multiple cycles of epithelial cell injury and fibroblast activation; currently, there is no clear etiology. Increasing evidence suggests that protein metabolism and amino acids play a crucial
Xiaoshu Guo, Xiaoshu Guo, Kai Xu, Lan Wang, Linke Ding, Wenwen Li, Xinsheng Zhang, Weiming Zhao, Ningdan Wang, Gaiping Wang, Wenyu Zhao, Ivan Rosas, Guoying Yu   +12 more
doaj   +1 more source

Hibiscus manihot L. flower extract induces anticancer activity through modulation of apoptosis and autophagy in A549 cells

Scientific Reports
Lung cancer is a major public health issue and heavy burden in China and worldwide due to its high incidence and mortality without effective treatment. It’s imperative to develop new treatments to overcome drug resistance.
Minglu Xu, Mengxia Zhao, Miaomiao Zhu, Hongmei Yuan, Zhongzheng Li, Peishuo Yan, Chi Ma, Huabin Zhao, Shenghui Wang, Ruyan Wan, Lan Wang, Guoying Yu   +11 more
doaj   +1 more source