Results 81 to 90 of about 279,445 (313)

Microengineered Gradient Hydrogels for Mechanobiology

Advanced Healthcare Materials, EarlyView.
Gradient hydrogels are used to mimic the mechanical heterogeneity in native tissues, offering powerful in vitro platforms to study cell‐material interactions in diverse pathophysiological contexts. Here, we present a comprehensive review of the design and experimental considerations for stiffness gradient hydrogels, discussing exemplary achievements ...
Shin Wei Chong, Deepu Ashok, Anna Waterhouse, Marcela M. M. Bilek, Daniele Vigolo   +4 more
wiley   +1 more source

A case of left atrial myxoma accompanied by pancytopenia and pathological findings suggestive of pulmonary hypertension

, 1974
A case of left atrial myxoma accompanied by peculiar symptoms is reported. A 15-year old boy had progressive congestive heart failure and three episodes of acute attacks of panctyopenia. The anemia was accompanied by helmet-shaped, broken red blood cells,
Ogawa, Katsuo, Ofuji, Tadashi, Sato, Keiichiro, Kawanishi, Koichi   +3 more
core   +1 more source

A randomised clinical trial of a digital self-management package for people with interstitial lung disease: the REBUILD-SM protocol

Respiratory Research
Background Interstitial lung disease (ILD) has a profound impact upon health-related quality of life (HRQoL) and mortality. Patients with ILD have identified their desire for tools to improve self-management. This study compares the clinical efficacy and
Carly Barton, Mariana Hoffman, Narelle S. Cox, Laura M. Glenn, Joanna Y. T. Lee, Ingrid Cox, Nicole S. L. Goh, Lauren K. Troy, John Mackintosh, Daniel C. Chambers, Ian N. Glaspole, Val Gebski, Anthony Keech, Andrew Palmer, Liliana Laranjo, Luke D. Knibbs, Yuben Moodley, Mark Brooke, Anne E. Holland, Tamera J. Corte   +19 more
doaj   +1 more source

A Systematic Study of GelMA‐Carbopol Bioinks for High‐Fidelity Extrusion 3D Bioprinting at Physiological Temperatures

Advanced Healthcare Materials, EarlyView.
Gonzalez Martinez and collaborators develop a strategy to formulate high performance GelMA‐based bioinks with low solids contents. The resulting bioinks enable 3D bioprinting at 37 °C of high‐fidelity structures with tunable mechanical properties that support high cell viability and function.
David A. González‐Martínez, Aidee V. Arizpe Tafoya, Eduardo González‐Martínez, Mabel Barreiro Carpio, Laura Daniela Serrano Andrade, Christopher T. N. Chow, Mohammadhossein Dabaghi, Jeremy A. Hirota, Jose M. Moran‐Mirabal   +8 more
wiley   +1 more source

Blood transcriptomic predicts progression of pulmonary fibrosis and associates natural killer cells.

, 2021
Rationale: Disease activity in idiopathic pulmonary fibrosis (IPF) remains highly variable, poorly understood, and difficult to predict. Objective: To identify a predictor using short-term longitudinal changes in gene-expression that forecasts future ...
Barros, Andrew J., Ma, Shwu-Fan, Maher, Toby M, Huang, Yong, Martinez, Fernando J., Herazo-Maya, Jose D., Molyneaux, Philip L., Oldham, Justin M, Bonham, Catherine A., Kim, John S, Molyneaux, Philip L, Moore, Bethany B., Maher, Toby M., Noth, Imre, Strek, Mary E, Oldham, Justin M., Adegunsoye, Ayodeji, Herazo-Maya, Jose D, Martinez, Fernando J, Kim, John S., Bonham, Catherine A, Moore, Bethany B, Unterman, Avraham, Liao, Shu-Yi, Barros, Andrew J, Kaminski, Naftali, Vij, Rekha, Strek, Mary E.   +27 more
core   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Idiopathic pulmonary fibrosis: evaluation of progression and prognosis after the ATS/ERS/JRS/ALAT statement 2011

, 2012
Objectives The prediction of usual interstitial pneumonia (UIP) progression and prognosis by the a application of HRCT criteria pattern recommended by ATS/ERS/JALAT guidelines 2011 Materials and methods Two radiologists after assessing the baseline HRCT ...
ROMEI, CHIARA
core  

Integrative analysis of gene expression and chromatin dynamics multi-omics data in mouse models of bleomycin-induced lung fibrosis

Epigenetics & Chromatin
Background Pulmonary fibrosis is a relentless and ultimately fatal lung disorder. Despite a wealth of research, the intricate molecular pathways that contribute to the onset of PF, especially the aspects related to epigenetic modifications and chromatin ...
Zhongzheng Li, Mengke Zhang, Yujie Zhang, Yulong Gan, Zhao Zhu, Jiawei Wang, Yanlin Zhou, Guoying Yu, Lan Wang   +8 more
doaj   +1 more source

Mediating effects of physical activity enjoyment on physical activity levels in adults with cystic fibrosis

Frontiers in Sports and Active Living
BackgroundThis study aimed to investigate the mediating effect of physical activity enjoyment (PAE) on various physical activity (PA) levels in adult people with cystic fibrosis (pwCF) concerning disease-specific and non-disease-specific factors.MethodsA
Matthias Welsner, Jin-Sun Schermaul, Jose Guillermo Ortiz, Liron Lechtenberg, Christian Taube, Florian Stehling, Wolfgang Gruber   +6 more
doaj   +1 more source

Transition Planning for Chronic Illnesses in the Time of COVID-19

Journal of Patient Experience, 2020
Transition from pediatric to adult care for those with chronic illnesses must have special considerations during the COVID-19 pandemic. The SARS-CoV-2 coronavirus has significantly disrupted social, economic, and health care practices globally.
William R Hunt MD, Rachel W Linnemann MD, Brandi Middour-Oxler DNP   +2 more
doaj   +1 more source