Results 191 to 200 of about 2,806,585 (261)

Application value of next generation sequencing technology for pathogen detection in patients with pulmonary infection and lung cancer. [PDF]

Am J Cancer Res
Xu L, Liu J, An X, Wu Y, Li X.
europepmc   +1 more source

Inhibition of MEKK3 Prevents Cerebral Cavernous Malformation Progression Via Restoring Endothelial Integrity and Restricting Microglial Activation

Advanced Science, EarlyView.
In this study, we demonstrate that aberrant MEKK3 signaling in endothelial cells and microglia drives the progression of cerebral cavernous malformations (CCMs). Furthermore, we identify DPDH as a potent small‐molecule MEKK3 inhibitor with substantial therapeutic potential for CCM treatment.
Weiwei Zheng, Suyun Yu, Liwenyu Chen, Jing Ma, Peiliang Shen, Chang Yu, Xiaoqing Xin, Qiuhong Shen, Jing Chen, Song Ke, Hao Liu, Xiaobing Jiang, Ruogu Qi, Juming Yan, Jia Li, Jaesung P. Choi, Yin Lu, Yang Zhao   +17 more
wiley   +1 more source

Mycobacterium riyadhense Pulmonary Infection, France and Bahrain

Emerging Infectious Diseases, 2012
Sylvain Godreuil, Hélène Marchandin, Anne-Laure Michon, Mikael Ponsada, Georges Chyderiotis, Patrick Brisou, Abdul Bhat, Gilles Panteix   +7 more
doaj   +1 more source

Clinical value of radial endobronchial ultrasound combined with metagenomic next-generation sequencing in the malignant tumors patients with pulmonary infection. [PDF]

Front Cell Infect Microbiol
Song Y, Zhang X, Wang H, Wang Y, Zhang S, Li Y, Cui X, Li X, Li Y, Wang J, Su J, Zheng Y, Gai W, Liu W.   +13 more
europepmc   +1 more source

Bioengineered Stroma‐Camouflaged Nanovesicles Disrupt the IDO1/CD276 Immunosuppressive Circuit to Reinvigorate Antitumor Immunity

Advanced Science, EarlyView.
Bioengineered stroma‐camouflaged nanovesicles (AM@UIO‐BMS/DOX) convert the immunosuppressive tumor niche into an immunoresponsive milieu by disrupting the IDO1/CD276 circuit. Anti‐CD276 membrane camouflage guides tumor accumulation and deep penetration, enabling controlled co‐delivery of DOX and the IDO1 inhibitor BMS‐986205.
Ziqi Zhang, Jing Luo, Mengdi Zhang, Jingying Zhuang, Yating Zheng, Yang Zhang, Zhihong Huang, Xinhua Lin, Shuzhen Xu, Hong Yao, Gang Liu, Bing Chen   +11 more
wiley   +1 more source

Inhalational therapy of pulmonary infection <i>via</i> macrophage-targeted nanoemulsions. [PDF]

Acta Pharm Sin B
Wang H, Xian J, Zhu G, Xie Z, Du G, Zhang Y, Yang L, Zhang Y, Li T, Zhou Y, Li W, Sun X, Wang C.   +12 more
europepmc   +1 more source

A Dual‐Delivery System Designed to Overcome EV‐Mediated Ferroptosis Resistance for Efficient Solid Tumor Therapy

Advanced Science, EarlyView.
(A) Establishment and characterization of the osteosarcoma‐targeted dual‐delivery nanoplatform mBAP1/siENO1@LNP‐OTP for simultaneous regulation of BAP1 and ENO1 in tumor cells. (B) After intravenous administration, mBAP1/siENO1@LNP‐OTP preferentially accumulates at tumor sites through OTP‐mediated targeting.
Yechao Shen, Zhenguo Cao, Zenan Wang, Liang Chen, Jiahao Zhang, Linjie Zeng, Boren Tan, Hengyuan Li, Jiashan Lai, Jiangchu Lei, Fanglu Chen, Peng Lin, Zhenxuan Shao, Zhan Wang   +13 more
wiley   +1 more source

Pathogen-Specific PET Imaging of Pulmonary Infection Using [¹⁸F]Fluoromannitol. [PDF]

Chem Biomed Imaging
Simpson SR, Simmons T, Echlin H, Wilde S, Perera SS, Villanueva P, Iverson A, Schuster A, Vogel P, Green A, Rosch J, Neumann KD.   +11 more
europepmc   +1 more source

RBMS1 Contributes to Early Arteriovenous Fistula Neointimal Remodeling Through Modulation of VSMC Phenotypic Responses

Advanced Science, EarlyView.
Postoperative arteriovenous fistulas exhibit increased RBMS1 in vascular smooth muscle cells (VSMCs). In experimental AVFs, RBMS1 overexpression aggravates, whereas deletion attenuates, neointimal hyperplasia. RBMS1 binds MPZL1 mRNA and promotes exon 5 skipping to generate MPZL1‐Δ5, which interacts with G3BP1 to activate AKT, driving VSMC proliferation,
Zongda Li, Chengwei Zhang, Xinying Yu, Shuang Yao, Yiting Lai, Xiaozhu Sun, Yao Zhao, Xiaoyu Lan, Tingting Hu, Wenjin Li, Zhenzhen Ma, Huimin Ma, Zihan Wang, Haihai Liang, Jundong Jiao   +14 more
wiley   +1 more source

Antisynthetase Syndrome Mimicking Pulmonary Infection: A Diagnostic Lesson From County-Managed Hospital. [PDF]

Clin Case Rep
Cheng J.
europepmc   +1 more source