Results 71 to 80 of about 4,104,503 (378)

A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini, Ezgi Oner, Mark P. Ward, Sinead Hurley, Brian David Henderson, Faye Lewis, Stephen P. Finn, Gerard J. Fitzmaurice, John J. O'Leary, Sharon O'Toole, Lorraine O'Driscoll, Kathy Gately   +11 more
wiley   +1 more source

Clinical Characteristics of Acute Exacerbations of Idiopathic Pulmonary Fibrosis and Involvement of Viral, Mycoplasma pneumoniae, and Chlamydophila pneumoniae Infections [PDF]

, 2013
Background and Objective:To clarify the clinical characteristics of acute exacerbation of idiopathic pulmonaryfibrosis (IPF) and the involvement of infections with pathogenic microorganisms and viruses inacute exacerbation.Methods:During the 12 years ...
Department of Pulmonary Medicine and Clinical Immunology, Dokkyo Medical University School of Medicine, Department of Pulmonary Medicine and Clinical Immunology, Dokkyo Medical University School of Medicine, Department of Pulmonary Medicine and Clinical Immunology, Dokkyo Medical University School of Medicine, Department of Pulmonary Medicine and Clinical Immunology, Dokkyo Medical University School of Medicine, Department of Pulmonary Medicine and Clinical Immunology, Dokkyo Medical University School of Medicine, Department of Pulmonary Medicine and Clinical Immunology, Dokkyo Medical University School of Medicine, Department of Pulmonary Medicine and Clinical Immunology, Dokkyo Medical University School of Medicine, Department of Pulmonary Medicine and Clinical Immunology, Dokkyo Medical University School of Medicine, Hirokuni Hirata, Kazuhiko Matsuno, Kazuki Obara, Kumiya Sugiyama, Makiko Anzai, Takeshi Fukuda, Yasuko Kikkawa, Yasutsugu Fukushima   +15 more
core   +1 more source

Inpatient Management of Bronchial Asthma for the Hospitalist [PDF]

, 2019
Asthma is a common inflammatory disease of the airways that leads to significant hospital utilization and health care cost around the world. Despite published guidelines, the diagnosis and treatment of acute asthma exacerbation varies widely due to ...
Guntur, Vamsi P., Hunter, Michael P., Krvavac, Armin, Regunath, Hariharan, Vaddi, Suman   +4 more
core   +1 more source

Evaluating Riociguat in the Treatment of Pulmonary Arterial Hypertension: A Real-World Perspective

Vascular Health and Risk Management, 2022
Andrew D Mihalek,1 Christopher D Scott,2 Sula Mazimba3 1Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Virginia, Charlottesville, VA, USA; 2Division of Thoracic Surgery, Department of Surgery, University of ...
Mihalek AD, Scott CD, Mazimba S
doaj  

Recent advances in chronic obstructive pulmonary disease pathogenesis: from disease mechanisms to precision medicine

Journal of Pathology, 2019
Chronic obstructive pulmonary disease (COPD) is a devastating lung disease with a high personal and societal burden. Exposure to toxic particles and gases, including cigarette smoke, is the main risk factor for COPD.
C. Brandsma, M. van den Berge, T. Hackett, G. Brusselle, W. Timens   +4 more
semanticscholar   +1 more source

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

Molecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi, Janelle‐Cheri Millen, Romela Irene Ramos, Jennifer A. Linehan, Timothy G. Wilson, Dave S. B. Hoon, Matias A. Bustos   +6 more
wiley   +1 more source

Effect of Oral Procaterol in Combination with Inhaled Corticosteroids in Adult Patients with Bronchial Asthma [PDF]

, 2008
Background:Bronchial asthma is considered to be a chronic airway inflammatory disease, and inhaledcorticosteroids play a central role in controlling airway inflammation.
Department of Pulmonary Medicine and Clinical Immunology,Dokkyo Medical University, Department of Pulmonary Medicine and Clinical Immunology,Dokkyo Medical University, Department of Pulmonary Medicine and Clinical Immunology,Dokkyo Medical University, Department of Pulmonary Medicine and Clinical Immunology,Dokkyo Medical University, Department of Pulmonary Medicine and Clinical Immunology,Dokkyo Medical University, Department of Pulmonary Medicine and Clinical Immunology,Dokkyo Medical University, Department of Pulmonary Medicine and Clinical Immunology,Dokkyo Medical University, Hironori Sagara, Kumiya Sugiyama, Mayumi Ohta, Ryuichi Kashima, Takenori Okada, Takeshi Fukuda, Tatsuo Yukawa   +13 more
core   +1 more source

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

Molecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić, Florian Lüke, Steffi Treitschke, Andrea Coluccio, Martin Hoffmann, Giancarlo Feliciello, Adithi Ravikumar Varadarajan, Xin Lu, Kathrin Weidele, Catherine Botteron, Silvia Materna–Reichelt, Felix Keil, Katja Evert, Florian Weber, Thomas Schamberger, Michael Althammer, Jirka Grosse, Dirk Hellwig, Christian Schulz, Stephan Seitz, Peter Ugocsai, Anke Schlenska‐Lange, Roman Mayr, Ulrich Kaiser, Wolfgang Dietmaier, Bernhard Polzer, Jens Warfsmann, Kamran Honarnejad, Tobias Pukrop, Daniel Heudobler, Christoph A. Klein, Christian Werno   +31 more
wiley   +1 more source

IL-33 and RANTES( Regulated on Activation, Normal T Cell Expressed and Secreted) in BAL Fluid in Asthma Patients Without Cigarette Smoking [PDF]

, 2013
Background:Inflammatory cytokines and chemokines have been reported to play important roles in thepathogenesis of bronchial asthma. However, no criteria for the classification of `smoker\u27 and `atopic\u27 in bronchialasthma have been defined.
Department of Pulmonary Medicine and Clinical Immunology, Dokkyo Medical University, Department of Pulmonary Medicine and Clinical Immunology, Dokkyo Medical University, Department of Pulmonary Medicine and Clinical Immunology, Dokkyo Medical University, Department of Pulmonary Medicine and Clinical Immunology, Dokkyo Medical University, Department of Pulmonary Medicine and Clinical Immunology, Dokkyo Medical University, Department of Pulmonary Medicine and Clinical Immunology, Dokkyo Medical University, Fumiya Fukushima, Hirokuni Hirata, Kumiya Sugiyama, Masamitsu Tatewaki, Takeshi Fukuda, Yasutsugu Fukushima   +11 more
core   +1 more source

Pectoralis Muscle Mass on Chest CT at Admission Predicts Prognosis in Patients with Pneumonia

Canadian Respiratory Journal, 2021
Background and Objectives. The concept of sarcopenia has been attracting attention in recent years, but its association with in-hospital mortality of patients with pneumonia is still unclear. Therefore, we investigated the relationship between pectoralis
Ryohsuke Yokosuka, Ryosuke Imai, Shosei Ro, Manabu Murakami, Kohei Okafuji, Atsushi Kitamura, Yutaka Tomishima, Torahiko Jinta, Naoki Nishimura, Tomohide Tamura, Osamu Takahashi   +10 more
doaj   +1 more source