Pulmonary surfactant and prostaglandin E2 in airway smooth muscle relaxation of human and male guinea pigs [PDF]
Physiological ReportsPulmonary surfactant serves as a barrier to respiratory epithelium but can also regulate airway smooth muscle (ASM) tone. Surfactant (SF) relaxes contracted ASM, similar to β2‐agonists, anticholinergics, nitric oxide, and prostanoids. The exact mechanism
J. Hanusrichterova +14 more
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Potential Therapeutic Applications of Pulmonary Surfactant Lipids in the Host Defence Against Respiratory Viral Infections [PDF]
Frontiers in Immunology, 2021 Pulmonary surfactant is a complex and highly surface-active material. It covers the alveolar epithelium and consists of 90% lipids and 10% proteins. Pulmonary surfactant lipids together with pulmonary surfactant proteins facilitate breathing by reducing ...
Jianjian Ji +7 more
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PLoS ONE, 2020 Smoke exposure is known to decrease total pulmonary surfactant and alter its composition, but the role of surfactant in chronic obstructive pulmonary disease (COPD) remains unknown. We aimed to analyze the compositional changes in the surfactant lipidome
Christina W Agudelo +8 more
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Effect of Amphotericin B on the Thermodynamic Properties and Surface Morphology of the Pulmonary Surfactant Model Monolayer during Respiration [PDF]
Molecules, 2023 During the COVID-19 pandemic, the treatment of pulmonary fungal infection faced noteworthy challenges. Amphotericin B has shown promising therapeutic effects as an inhalation treatment for pulmonary fungal infections, especially those associated with the
Juan Wang +3 more
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Lung surfactant in subacute pulmonary disease [PDF]
Respiratory Research, 2002 Pulmonary surfactant is a surface active material composed of both lipids and proteins that is produced by alveolar type II pneumocytes. Abnormalities of surfactant in the immature lung or in the acutely inflamed mature lung are well described.
Spragg Roger G, Devendra Gehan
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Prospective, Non-Blinded, Randomized Controlled Trial of Pulmonary Surfactant Administration Guided by Lung Ultrasound in Preterm Infants with Gestational Age < 32 Weeks. [PDF]
Children (Basel)Zhang J +7 more
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Pulmonary surfactant system [PDF]
Eurasian Journal of Veterinary SciencesPulmonary surfactant, a phospholipid-protein complex that lines the alveoli and small airways of the lungs, is secreted by type ll alveolar epithelial cells. Recognized functions of surfactant are (1) maintaining proper humidity of the alveolar wall; (2)
Zafer Durgun, Ercan Keskin
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Insights Gained Into the Treatment of COVID19 by Pulmonary Surfactant and Its Components
Frontiers in Immunology, 2022 Pulmonary surfactant constitutes an important barrier that pathogens must cross to gain access to the rest of the organism via the respiratory surface.
Dan Li +6 more
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European Respiratory Review, 2021 Pulmonary surfactant is a crucial and dynamic lung structure whose primary functions are to reduce alveolar surface tension and facilitate breathing.
Nadia Milad, Mathieu C. Morissette
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Effect of Nebulized Bovine Surfactant for Experimental Otitis Media with Effusion [PDF]
Clinical and Experimental Otorhinolaryngology, 2010 ObjectivesIn this study, we evaluated the efficacy of nebulized bovine pulmonary surfactant on experimentally induced otitis media with effusion (OME) in guinea pigs.MethodsTwenty guinea pigs were divided into three groups.
Chul Ho Jang +5 more
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