Results 61 to 70 of about 40,759 (154)

Expression profiles of hydrophobic surfactant proteins in children with diffuse chronic lung disease

Respiratory Research, 2005
Background Abnormalities of the intracellular metabolism of the hydrophobic surfactant proteins SP-B and SP-C and their precursors may be causally linked to chronic childhood diffuse lung diseases.
Guttentag Susan, Braun Annika, Steinecker Manuela, Tredano Mohammed, Schumacher Silja, Griese Matthias, Beers Michael F, Bahuau Michel   +7 more
doaj   +1 more source

Epithelial cell–derived secreted and transmembrane 1a signals to activated neutrophils during pneumococcal pneumonia [PDF]

, 2016
Airway epithelial cell responses are critical to the outcome of lung infection. In this study, we aimed to identify unique contributions of epithelial cells during lung infection.
Belkina, Anna C., Deng, Jane C., Gower, Adam C., Jones, Matthew R., Kamata, Hirofumi, Lung, Wing Yi, Mizgerd, Joseph P., Quinton, Lee J., Ramirez, Maria I., Wasserman, Gregory A., Yamamoto, Kazuko, Yuen, Constance K., Zabinski, Mary C.   +12 more
core   +1 more source

Clinical significance of serum surfactant protein D in patients with rheumatoid arthritis-associated interstitial lung diseases

Egyptian Journal of Chest Disease and Tuberculosis, 2016
Background: Rheumatoid arthritis (RA) is a chronic inflammatory disease that affects approximately 1% of the population, and pulmonary involvement is common.
Ashraf E. Sileem, Ahmed Mohamed Said, Ahmed Mohamed Alsowey, Sameh A. Soliman   +3 more
doaj   +1 more source

In vivo clearance of surfactant lipids during acute pulmonary inflammation. [PDF]

, 2004
Background A decrease in pulmonary surfactant has been suggested to contribute to the lung dysfunction associated with pulmonary inflammation. A number of studies have implicated surfactant clearance as a possible mechanism for altered pool sizes.
J Goerke, E Crouch, TJ Gregory, U Pison, A Gunther, J Vanderzwan, BA Holm, TC Bailey, JC McIntosh, CJ Viviano, K Sugahara, JF Lewis, J Malloy, JR Wright, JR Wright, OA Quintero, S Uhlig, H Fehrenbach, EG Bligh, CG Duck-Chong, AJ Tenner, LG Dobbs, JF Herbein, KL Hartshorn, ED Rider, A Lopez, O Gurel   +26 more
core   +2 more sources

DNA repair systems and the pathogenesis of Mycobacterium tuberculosis: varying activities at different stages of infection [PDF]

, 2010
Mycobacteria, including most of all MTB (Mycobacterium tuberculosis), cause pathogenic infections in humans and, during the infectious process, are exposed to a range of environmental insults, including the host's immune response.
Adams, Afanasev, Alina E. Gorna, Aly, Arnold, Bacon, Banu, Bergval, Betts, Boshoff, Boshoff, Bostanabad, Burney, Capelli, Chan, Chan, Cheng, Cooper, Cubillos-Ruiz, Darwin, Darwin, Das, Davis, Dos Vultos, Dubnau, Durbach, Farnia, Fennelly, Filliol, Fleischmann, Flint, Fontan, Friedberg, Frischkorn, Fu, Fu, Gaynor, Gordhan, Graham, Grishko, Guthlein, Hampshire, Hazbon, Hughes, Jain, Jaroslaw Dziadek, Jiao, Kapur, Karakousis, Karakousis, Karunkaran, Katti, Kesavan, Kim, Ko, Ko, Korycka-Machala, Krokan, Kurthkoti, Kurthkoti, Lari, Lever, Loudon, MacMicking, Malshetty, Martinez, Mokrousov, Moller, Movahedzadeh, Mulder, Munoz-Elias, Muttucumaru, Nguyen, Niemann, Nikolayevskyy, Nouvel, O'sullivan, Olano, Peccia, Peccia, Pitcher, Rachman, Rachman, Rad, Ramaswamy, Richard P. Bowater, Riley, Saito, Sander, Sassetti, Sassetti, Saunders, Schnappinger, Schwab, Sherman, Sinha, Sinha, Smeulders, Springer, Srivastava, Stephanou, Talaat, Talaat, Tang, Tsai, Venkatesh, Vilcheze, Voskuil, Voskuil, Waddell, Wanner, Warner, Weikert, Wiid, Wiseman, World Health Organization, Zaczek, Zainuddin   +117 more
core   +1 more source

In vivo evaluation of the inhibitory capacity of human plasma on exogenous surfactant function [PDF]

, 1994
Objective: The adult respiratory distress syndrome (ARDS) and neonatal respiratory distress syndrome (RDS) are characterized by high permeability pulmonary edema which contains plasma-derived proteins inhibiting pulmonary surfactant function.
Eijking, E.P. (Eric), Gommers, D.A.M.P.J. (Diederik), Lachmann, B.F. (Burkhard), So, K.L.   +3 more
core   +1 more source

Genetic Association of Pulmonary Surfactant Protein Genes, SFTPA1, SFTPA2, SFTPB, SFTPC, and SFTPD With Cystic Fibrosis

Frontiers in Immunology, 2018
Surfactant proteins (SP) are involved in surfactant function and innate immunity in the human lung. Both lung function and innate immunity are altered in CF, and altered SP levels and genetic association are observed in Cystic Fibrosis (CF).
Zhenwu Lin, Nithyananda Thorenoor, Rongling Wu, Susan L. DiAngelo, Meixia Ye, Meixia Ye, Neal J. Thomas, Xiaojie Liao, Tony R. Lin, Stuart Warren, Joanna Floros, Joanna Floros   +11 more
doaj   +1 more source

The Evolution of Cell Communication: The Road not Taken. [PDF]

, 2009
In the post-genomic era the complex problem of evolutionary biology can be tackled from the top-down, the bottom-up, or from the middle-out. Given the emergent and contingent nature of this process, we have chosen to take the latter approach, both as a ...
Rehan, VK, Torday, JS
core   +1 more source

Martini compatible coarse-grained model of polyethylenimine for pulmonary gene delivery

Scientific Reports
Pulmonary gene delivery has demonstrated high specificity for respiratory diseases, offering great control on dosage of therapeutics and side effects. On the other hand, intrinsic barriers in pulmonary systems impose new challenges such as crossing the ...
Graham Lunt, Niloofar Hashemi, Subhamoy Mahajan, Tian Tang   +3 more
doaj   +1 more source

Surfactant status and respiratory outcome in premature infants receiving late surfactant treatment. [PDF]

, 2019
BACKGROUND:Many premature infants with respiratory failure are deficient in surfactant, but the relationship to occurrence of bronchopulmonary dysplasia (BPD) is uncertain.
A Bhandari, A Greenough, AH Jobe, AM Gibson, BB Poindexter, Cheryl Chapin, EG Bligh, FS Cole, G Natarajan, G Verlato, GS Pryhuber, Hart Horneman, JD Merrill, JD Merrill, JJ Coalson, JK Roberts, K Bohlin, KC Wai, LA Katz, LM Askie, M Facco, M Ikegami, M Laughon, M Torresin, Mark R. Segal, PE Cogo, Philip L. Ballard, PL Ballard, PL Ballard, R Bissinger, R Development Core Team., RA Ballard, RA Ballard, RA Ehrenkranz, RA Veldhuizen, RA Veldhuizen, RL Keller, RL Keller, Roberta A Ballard, Roberta L. Keller, T Ueda, T Yamada, TF Yeh, VP Carnielli, William E. Truog, WN Venables   +45 more
core   +1 more source