Results 131 to 140 of about 22,696 (353)

Clathrin Light Chain B Drives Hepatocellular Carcinoma Progression Through Dual Mechanisms: Small Extracellular Vesicle‐Mediated Angiogenesis and the NF‐κB–PCLAF Signaling Axis

Advanced Science, EarlyView.
Clathrin Light Chain B (CLTB) drives hepatocellular carcinoma progression through dual pathways: intracellularly, it activates the NF‐κB–PCLAF axis to enhance small extracellular vesicle (sEV) uptake and tumor proliferation; extracellularly, CLTB‐enriched sEVs bind SH3KBP1 to inhibit its degradation, inducing angiogenesis and vascular leakage ...
Xiaoke Sun, Junchen Guo, Ning Zhao, Guanghua Cui, Yun Bai, Meijuan Ding, Yi Xu, Yu Yang   +7 more
wiley   +1 more source

Nanocarriers made from non-ionic surfactants or natural polymers for pulmonary drug delivery. [PDF]

, 2015
Treatment by the pulmonary route can be used for administration of drugs that act locally in the lungs (e.g. treatment of lung cancer, chronic obstructive pulmonary disease, asthma) or non-invasive administration of drugs that act systemically.
Carter, Katharine, Puig, Mireia
core  

Pulmonary ischemia and surfactant in the neonatal lung [PDF]

, 1971
Ronald S. Bloom, Cherill M. Parmentier, C R Parks, David E Woodrum, W. Alan Hodson, Ralph Wedgwood   +5 more
openalex   +1 more source

Modulation of Aging Diseases via RAGE Targets: A Dietary Intervention Review

Advanced Science, EarlyView.
This paper analyzes RAGE ligand‐binding mechanisms and signaling, proposing intervention strategies targeting these interactions. It emphasizes dietary polyphenols, polysaccharides, and terpenoids delivered via functional foods for anti‐aging. These compounds offer long‐term, safe intervention through dietary supplementation, providing dual nutritional
Qian Wu, Jia Yan, Yuyan Zhang, Xiaozhi Ming, Siqi Chen, Zhichao Zou, Nianjie Feng, Jianbo Xiao   +7 more
wiley   +1 more source

A Single‐Component Adhesive Sponge Based on Blood‐Triggered and Autopenetrative Adhesion for Robust Vascular Closure

Advanced Science, EarlyView.
This study presents MonoSeal, a single‐component adhesive sponge powered by the novel Autopenetrative Adhesion (APA) mechanism. Unlike traditional adhesives, which require external stimuli, APA enables strong tissue adhesion under dynamic, high‐pressure bleeding conditions. MonoSeal's ability to autonomously seal large‐size arterial defects underscores
Rong Wang, Weishi Zheng, Yuxuan Huang, Rui Zhang, Yi Zhang, Jingying Yan, Yuqing Gu, Jingyun Xi, Tun Yuan, Hua Su, Xianzhu Zhang, Xiaozhao Wang, Shaohui Xiong, Zhenfeng Cheng, Hongwei Ouyang, Yi Hong   +15 more
wiley   +1 more source

A mouse model of lung ischemia–reperfusion injury with reversible left hilar entrapment

Animal Models and Experimental Medicine, EarlyView.
A Novel Reversible Left Hilar Entrapment Model for Mouse Lung Ischemia‐Reperfusion Injury with Visual Tracheal Intubation and Live Knot Technique. Abstract Lung ischemia–reperfusion injury (LIRI), an acute lung injury syndrome triggered by lung transplantation or distal organ ischemia, has long been a difficult and hot issue in clinical research.
GuangDong Weng, Yao Chen, ShanQing Bao, ChengXin Zhang, WenHui Gong   +4 more
wiley   +1 more source

Research advances in dysphagia animal models

Animal Models and Experimental Medicine, EarlyView.
This review systematically summarizes the establishment, evaluation, and detection of dysphagia animal models in stroke, Parkinson's disease (PD), and amyotrophic lateral sclerosis (ALS) in three kinds of experimental animals (including rodents, nonhuman primates, and other mammals), providing a basis for the selection of appropriate animal models of ...
Junhui Bai, Keling Cheng, Nannan Zhang, Yunfang Chen, Jun Ni, Zhiyong Wang   +5 more
wiley   +1 more source

Dihydrotestosterone Inhibits Fetal Rabbit Pulmonary Surfactant Production [PDF]

, 1982
Heber C. Nielsen, Howard M. Zinman, John S. Torday   +2 more
openalex   +1 more source

Diosgenin ameliorates silica‐induced tuberculosis in rats

Animal Models and Experimental Medicine, EarlyView.
Silicosis increases susceptibility to tuberculosis due to impaired macrophage function and oxidative stress. This study demonstrates that diosgenin, a steroidal saponin, significantly inhibits Mycobacterium smegmatis (IC₅₀ = 0.006 μg/mL), reduces lung fibrosis, and restores antioxidant enzyme levels (↑SOD, ↑CAT, ↓MDA) in silica‐exposed rats ...
Williams Asamoah Adu, Selase Ativui, Michael Ofori, George Owusu, Cynthia Amaning Danquah, Paul Poku Sampene Ossei   +5 more
wiley   +1 more source

Antimicrobial Behavior of Simvastatin‐Loaded Solution Blow‐Spun PLA/PEO/HA Scaffolds

Journal of Applied Polymer Science, EarlyView.
Schematic for fiber spinning. ABSTRACT The development of three‐dimensional scaffolds with suitable biological properties is of crucial importance in bone repair. Incorporating antimicrobial functionality into these scaffolds can further enhance their clinical efficacy by helping prevent infections, particularly in patients undergoing orthopedic ...
João P. A. Caribé, Lucas R. F. Figueiredo, Rafaela R. Arimatéia, Raquel. S. Leite, Willams T. Barbosa, Josiane D. V. Barbosa, Carine R. Teixeira, Katharine V. S. Hodel, Juliana P. N. Souza, Jaqueline L. Vieira, Luís. A. L. Santos, Romualdo R. Menezes, Gelmires A. Neves, Kaline N. Ferreira, Eliton S. Medeiros, Nilmar Souza, Imarally V. S. R. Nascimento, Adillys M. C. Santos   +17 more
wiley   +1 more source