Results 171 to 180 of about 1,349,045 (346)

Chronic Low‐Dose Unsymmetrical Dimethylhydrazine Exposure in Rats: Multiorgan Mechanisms and Biomarker Identification

Journal of Applied Toxicology, EarlyView.
ABSTRACT Unsymmetrical dimethylhydrazine (UDMH), a highly toxic rocket propellant with known multiorgan effects, requires urgent characterization of its chronic low‐dose toxicity. Using an integrated approach including exploratory transcriptomics (n = 3/group) and metabolomic (n = 4/group) approaches in male Sprague–Dawley rats exposed to high‐dose ...
Fuzhou Liu, Bing Liu, Keli Wang, Xiaoyu Wang, Zhen Sun, Xiaojuan Pan, Zengming Zhao   +6 more
wiley   +1 more source

Comparing Imaging Depth of Intravital Lung Imaging Using Perfluorocarbon‐Based Liquid Ventilation With Tissue Clearing for Deep‐Tissue Imaging

Journal of Biophotonics, EarlyView.
Partial liquid ventilation with oxygenized perfluorocarbon (PFC) is used to assess the limitations of imaging depth, caused by the refractive index mismatch between air and surfactants in the mouse lung. PFC does not help to overcome this limitation. Only removing scattering lipids and decolorization ex vivo, with tissue optical clearing, enhance the ...
Pascal Detampel, Wolf Heusermann, Katarzyna M. Wojcik, Bryan G. Yipp, Matthias Amrein   +4 more
wiley   +1 more source

Liquid-Crystalline Collapse of Pulmonary Surfactant Monolayers [PDF]

, 2003
William R. Schief, Meher Antia, Bohdana M. Discher, Stephen B. Hall, Viola Vogel   +4 more
openalex   +1 more source

HOXA5 Suppresses NEK7‐Mediated Alveolar Epithelial Pyroptosis in Acute Lung Injury by Transcriptionally Inhibiting KAT2A

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Alveolar epithelial cell pyroptosis exacerbates inflammation and tissue damage by releasing inflammatory mediators, thereby promoting the development of acute lung injury (ALI). However, the fundamental mechanism underlying alveolar epithelial cell pyroptosis in ALI has not yet been elucidated. Lipopolysaccharide (LPS) was used to simulate ALI
Lei Wang, Heng Fan, Qi Wang, Cheng‐Jie Jiang, Dan‐Hui Li, Ji‐Hui Ye   +5 more
wiley   +1 more source

Pseudomonas aeruginosa Elastase Provides an Escape from Phagocytosis by Degrading the Pulmonary Surfactant Protein-A

, 2011
Zhizhou Kuang, Yonghua Hao, Brent E. Walling, Jayme L. Jeffries, Dennis E. Ohman, Gee W. Lau   +5 more
openalex   +2 more sources

Lung surfactant in subacute pulmonary disease [PDF]

, 2002
Gehan Devendra, Roger G. Spragg
openalex   +1 more source

Congestion, decongestion, renal function and diuretics in (ESC) heart failure

ESC Heart Failure, Volume 12, Issue 2, Page 730-732, April 2025.
Jan Biegus, Piort Gajewski, Piotr Ponikowski   +2 more
wiley   +1 more source

Deubiquitinase USP7 Regulates Neutrophil Extracellular Trap Formation and Inflammation in Lipopolysaccharide‐Treated Mice Through ICAM‐1 Expression

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Sepsis is typified by organ failure due to an unchecked host reaction to infection. This study aims to explore the mechanism of ubiquitin‐specific peptidase 7 (USP7) in sepsis with the involvement of intercellular adhesion molecule‐1 (ICAM‐1).
Hui Xu, Qi Wang, Jing‐Xian Fan, Yong‐Fu Xu, Jiao Yu   +4 more
wiley   +1 more source

Pulmonary surfactant and prostaglandin E₂ in airway smooth muscle relaxation of human and male guinea pigs

Juliana Hanusrichterová, M Kolomazník, Romana Barošová, Jana Adamčáková, Daniela Mokrá, Juraj Mokrý, Henrieta Škovierová, Margaret M. Kelly, Elaine de Heuvel, Shahina Wiehler, David Proud, Hua Shen, Priyanka Mukherjee, Mathias Amrein, Andrea Čalkovská   +14 more
openalex   +1 more source

Mouse Vocal Fold Permeability In Vivo: Effects of Novel Low‐Tech Injury and Instillation Methods

The Laryngoscope, EarlyView.
Improving experimental mouse vocal fold injury and instillation approaches is necessary to advance preclinical models of laryngeal disease. We have successfully repurposed low‐tech, quick, and reliable injury and instillation methods established in respiratory research. Using these methods, we show that murine vocal fold epithelium is inherently highly
Renee E. King, Ella T. Ward‐Shaw, Paul F. Lambert   +2 more
wiley   +1 more source