Results 101 to 110 of about 206,866 (317)

Genetic association and expression studies indicate a role of toll-like receptor 8 in pulmonary tuberculosis. [PDF]

, 2008
Despite high rates of exposure, only 5-10% of people infected with Mycobacterium tuberculosis will develop active tuberculosis (TB) disease, suggesting a significant role for genetic variation in the human immune response to this infection.
Crevel, R. van, Carine Bonnard, Hazel E E Wong, Sahiratmadja Edhyana, Wong, Hazel EE, Ottenhoff, THM, Nejentsev, S., van de Vosse, Esther, Bonnard, C, Ottenhoff, T.H., Martin L Hibberd, Jeffrey S Szeszko, Ottenhoff Tom H. M., Reinout van Crevel, Balabanova, Yanina, van Crevel Reinout, Nejentsev Sergey, Seielstad, M., Ottenhoff, Tom HM, Tom H M Ottenhoff, van Crevel, Reinout, Sahiratmadja, Edhyana, Wong, H.E., Yanina Balabanova, Szeszko Jeffrey S., Hari Dass, Ranjeeta, Alisjahbana Bachti, Szeszko, Jeffrey S, Edhyana Sahiratmadja, Bonnard, Carine, Bachti Alisjahbana, Szeszko, J.S., Francis Drobniewski, Davila, Sonia, Alisjahbana, B., Hibberd, M.L., Hari Dass, R., Balabanova, Y., Alisjahbana, Bachti, van de Vosse, E, Alisjahbana, B, Bonnard Carine, Hari Dass Ranjeeta, Sonia Davila, Ranjeeta Hari Dass, Nejentsev, S, Szeszko, JS, Nejentsev, Sergey, Davila, S, Sergey Nejentsev, Seielstad Mark, Dass, Ranjeeta Hari, van Crevel, R, Bonnard, C., Dass, RH, Hibberd Martin L., Balabanova Yanina, van de Vosse Esther, Vosse, E. van de, Mark Seielstad, Seielstad, M, Hibberd, ML, Balabanova, Y, Davila, S., Drobniewski, F, Sahiratmadja, E., Davila Sonia, Drobniewski, Francis, Seielstad, Mark, Drobniewski, F., Wong, HEE, Hibberd, Martin L, Sahiratmadja, E, Esther van de Vosse, Wong Hazel E. E., Drobniewski Francis   +75 more
core   +1 more source

Critical role of molecular test in early diagnosis of gastric tuberculosis: a rare case report and review of literature

BMC Infectious Diseases, 2019
Backgroud Early diagnosis of gastric tuberculosis is often challenging because the disease is very rare and its clinical manifestation is nonspecific and misleading. To raise the awareness and emphasize early diagnosis of gastric tuberculosis, we present
Jun Ma, Hongyun Yin, Huikang Xie
doaj   +1 more source

Tobramycin pharmacokinetic and pharmacodynamic targets in people with cystic fibrosis

British Journal of Clinical Pharmacology, EarlyView.
Intravenous tobramycin is a first‐line treatment for Pseudomonas aeruginosa infection in people with cystic fibrosis (CF). Tobramycin exhibits concentration‐dependent activity; however, excess drug exposure can lead to nephrotoxicity and ototoxicity. While dosing typically targets serum peak (Cmax) and trough (Cmin) concentrations, the area under the ...
Kiera H. Harwood, Sarah Bannister, Stephen Duffull, April Martinez, Sarath Ranganathan, Shivanthan Shanthikumar, Amanda Gwee   +6 more
wiley   +1 more source

Enhanced strategies for cuproptosis‐like death in bacterial infection treatment

BMEMat, EarlyView.
This review summarizes and examines the molecular mechanisms underlying cuproptosis‐like death. Furthermore, multi‐strategy efficacy enhancement and potential enhancement approaches are analyzed. Abstract Copper, a classical antibacterial metal, has long been of interest and widely used in medical and public health applications.
Wenqi Wang, Bolong Xu, Ruiyuan Zhu, Hengshuo Gui, Tian Xia, Shaokai Liu, Huiyu Liu, Xianwen Wang   +7 more
wiley   +1 more source

A Randomized Controlled Trial of Standard Versus Intensified Tuberculosis Diagnostics on Treatment Decisions by Physicians in Northern Tanzania. [PDF]

, 2014
Routine tuberculosis culture remains unavailable in many high-burden areas, including Tanzania. This study sought to determine the impact of providing mycobacterial culture results over standard of care [unconcentrated acid-fast (AFB) smears] on ...
Thielman, Nathan M., Njau, Boniface N., Bartlett, John A., Tribble, A.C, Njau, Boniface N, Kibiki, Gibson S, Morrissey, Anne B, Morpeth, Susan C., Crump, John A., Morpeth, Susan C, John A Crump, Lancaster, Kathryn E, Shein-Chung Chow, Jason E Stout, Maro, Venance P, Hamilton, C.D, Lancaster, K.E, Stout, Jason E., Thielman, Nathan M, Stout, Jason E, Carol D Hamilton, Maro, V.P, Nathan M Thielman, Morpeth, S.C, Coleen K Cunningham, Morrissey, Anne B., Cunningham, C.K, Chow, Shein-Chung, Msuya, Levina J., Tribble, Alison C., Boniface N Njau, Tribble, Alison C, John F Shao, Shao, John F., Stout, J.E, Hamilton, Carol D, Reddy, E.A, Chow, S.-C, Msuya, Levina J, Hamilton, Carol D., Kibiki, Gibson S., Elizabeth A Reddy, Thielman, N.M, Morrissey, A.B, Msuya, L.J, Kathryn E Lancaster, Cunningham, Coleen K., Schimana, W, Werner Schimana, Lancaster, Kathryn, Crump, John A, Crump, J.A, Maro, Venance P., Reddy, Elizabeth A., Bartlett, J.A, Alison C Tribble, Kibiki, G.S, Shao, J.F, Susan C Morpeth, Njau, B.N, Venance P Maro, Anne B Morrissey, Cunningham, Coleen K, Levina J Msuya, Gibson S Kibiki, John A Bartlett, Shao, John F, Schimana, Werner, Reddy, Elizabeth A, Bartlett, John A   +69 more
core   +1 more source

Metal nanostructure‐coupled label‐free localized surface plasmon resonance biosensors for rapid and sensitive disease diagnosis

BMEMat, EarlyView.
LSPR biosensing enables rapid, sensitive, and low‐sample‐volume detection of biomarkers, with broad applications in diagnosing cancer, infectious, and chronic diseases. Advances in nanostructure design, micro/nanofabrication, and microfluidic integration have expanded the potential of LSPR sensors in biomedical diagnostics.
Zhaoxin Geng, Yunfei Sha, Jiongyan Yang, Hongru Yang, Xiao Liang   +4 more
wiley   +1 more source

The Role of Diabetes Co-Morbidity for Tuberculosis Treatment Outcomes: A Prospective Cohort Study from Mwanza, Tanzania. [PDF]

, 2012
Due to the association between diabetes and pulmonary tuberculosis (TB), diabetes may threaten the control of TB. In a prospective cohort study nested in a nutrition trial, we investigated the role of diabetes on changes in anthropometry, grip strength ...
Range Nyagosya, Aabye Martine, Christensen, Dirk Lund, Praygod, George Amani, Praygod George, Martinussen Torben, George Praygod, Jeremiah Kidola, Maria Faurholt-Jepsen, Faurholt-Jepsen Maria, Martine Grosos Aabye, Aabye, Martine Grosos, Witte, Daniel Rinse, Andersen, Åse Bengård, Martinussen, Torben, Andersen Åse, Dirk Lund Christensen, Changalucha John, Nyagosya Range, Daniel Rinse Witte, Krarup, Henrik, Range, Nyagosya, Christensen Dirk, Henrik Krarup, Faurholt-Jepsen, Maria, Witte Daniel, Changalucha, John, Daniel Faurholt-Jepsen, Kidola, Jeremiah, Faurholt-Jepsen Daniel, Friis, Henrik, John Changalucha, Henrik Friis, Krarup, Henrik Bygum, Torben Martinussen, Faurholt-Jepsen, Daniel, Friis Henrik, Åse Bengård Andersen, Praygod, George, Kidola Jeremiah, Krarup Henrik   +40 more
core   +1 more source

Pulmonary Tuberculosis [PDF]

Pulmonary Medicine, 2013
Anete Trajman, José R. Lapa e Silva, Margareth Dalcolmo, Jonathan E. Golub   +3 more
openaire   +3 more sources

Fungal Antimicrobial Resistance: Mechanisms, Drivers, and Global Clinical Burden

ChemFoodChem, EarlyView.
ABSTRACT Fungal antimicrobial resistance (AMR) is a growing concern for world health caused by an increase in multidrug‐resistant infections, an increase in environmental reservoirs, and the ineffectiveness of current antifungal treatments. Fungal infections continue to be largely excluded from AMR initiatives while causing over 1.6 million deaths ...
Bikash Baral
wiley   +1 more source

Characteristics and early outcomes of patients with Xpert MTB/RIF-negative pulmonary tuberculosis diagnosed during screening before antiretroviral therapy. [PDF]

, 2012
BACKGROUND: A proportion of patients with tuberculosis diagnosed by sputum culture during screening before antiretroviral therapy (ART) have false-negative Xpert MTB/RIF assay results (Xpert-negative tuberculosis).
Vogt, Monica, Kerkhoff, Andrew D, Lawn, Stephen D, Ghebrekristos, Yonas, Whitelaw, Andrew, Wood, Robin   +5 more
core   +1 more source