Results 111 to 120 of about 918,150 (305)
iMeta, EarlyView.The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li +29 more
wiley +1 more source
BMC Pulmonary MedicineObjective Adenosine deaminase (ADA) is a widely-used diagnostic test for tuberculous pleural effusion (TPE), but its accuracy, optimal diagnostic threshold and relevant factors are controversial or unclear. We aimed to reassess these diagnostic variables
Chi Yang +6 more
doaj +1 more source
Monocyte inflammation and adaptive immune dysfunction in severe Klebsiella pneumoniae pneumonia
iMeta, EarlyView.Severe Klebsiella pneumoniae pneumonia combines intense inflammation with failure to control infection, yet the cellular basis is unclear. Using a severity‐focused single‐cell atlas of 708,894 peripheral blood mononuclear cells from 100 individuals, complemented by plasma protein measurements and flow cytometry, we show that disease severity redirects ...
Hongquan Chen +23 more
wiley +1 more source
Polymorphism in the EREG gene confers susceptibility to tuberculosis
BMC Medical Genetics, 2019 Background Host genetic factors affect the immune response to Mycobacterium tuberculosis (Mtb) infection as well as the progression of the disease. Epiregulin (EREG) belongs to the epidermal growth factor (EGF) family, which binds to the epidermal growth
Wen Cao +7 more
doaj +1 more source
Blood vessels and their construction in the cavities of pulmonary tuberculosis [PDF]
, 1958 First of all, we investigated the origin, the construction and distribution of the bronchial arteries and veins in adult rabbits, and then observed various changes of the blood vessels in experimental cavities and caseous foci and also studied the ...
Takata, Jun-nosuke, Hiraki, Kiyoshi
core +1 more source
iNew Medicine, EarlyView.ABSTRACT Objective Tofacitinib is a Janus kinase (JAK) inhibitor approved for the treatment of moderate‐to‐severe rheumatoid arthritis (RA). However, its synovium‐related molecular mechanisms, particularly its regulatory effect on fibroblast‐like synoviocyte (FLS) migration, remain incompletely understood.
Shuqi Fang +13 more
wiley +1 more source
Epidemiology of Tuberculosis in Iran (2001-08) [PDF]
Background and Objective: The characterization of any disease have important role for the evaluation and control strategy and programming of diseases. This study was done to determine the epidemiology of Tuberculosis in Iran during 2001-08. Materials and
ارسنگ, شهرام +2 more
core
Delay in Tuberculosis Case-Finding and Treatment in Mwanza, Tanzania. [PDF]
, 2000 Health facilities in Mwanza region, Tanzania. To determine factors responsible for delay from onset of symptoms of pulmonary tuberculosis to initiation of treatment.
Wandwalo, E R, Mørkve, O
core
Characteristics and early outcomes of patients with Xpert MTB/RIF-negative pulmonary tuberculosis diagnosed during screening before antiretroviral therapy. [PDF]
, 2012 BACKGROUND: A proportion of patients with tuberculosis diagnosed by sputum culture during screening before antiretroviral therapy (ART) have false-negative Xpert MTB/RIF assay results (Xpert-negative tuberculosis).
Vogt, Monica +5 more
core +1 more source
Cytotoxic and Genotoxic Effects in Buccal Cells of Sandstone Quarry Workers
Journal of Applied Toxicology, EarlyView.ABSTRACT Mineral extraction poses significant occupational health risks, particularly from respirable crystalline silica exposure. Sandstone quarrying generates substantial dust, yet evidence of its genotoxic effects remains limited. This study investigated cytogenotoxic damage in sandstone quarry workers from southern Brazil using the buccal ...
Ana Carolina de Quadros Duarte +6 more
wiley +1 more source