Results 81 to 90 of about 206,866 (317)
Integrating One Health to Mitigate the Emergence and Spread of Antimicrobial Resistance in Livestock and Aquaculture
Animal Research and One Health, EarlyView.Antimicrobial resistance (AMR) is an escalating global threat driven by antimicrobial use in aquaculture and livestock. Resistant pathogens and genes can spread across humans, animals, and the environment through interconnected ecosystems. Using a One Health approach, this review emphasizes antimicrobial stewardship, regulatory strengthening, enhanced ...Mir Mohammad Ali, Delower Hossain, Ridwan Olamilekan Adesola, Anum Hanif, Shamsaldeen Ibrahim Saeed, Muhammad Abdul Mannan, Anoar Jamai Masroure, Kazi Estieque Alam, Md Kamal Hossain, Sabiha Zarin Tasnim Bristi, Md Jisan Ahmed +10 morewiley +1 more sourceHyperferritinemia in Pulmonary Tuberculosis [PDF]
Indian Journal of Clinical Biochemistry, 2012 High ferritin levels have been found to be associated with non infectious as well as infectious causes including tuberculosis. This is one case report of 41 year old male who presented with cough with expectoration. The patient had Multi drug resistant tuberculosis (MDRTB) and type 2 diabetes mellitus.Benedicta, D'Souza, Sulekha, Sinha, Poornima, Manjrekar, Vivian, D'Souza +3 moreopenaire +2 more sourcesEfficacy and Safety of Guselkumab in Participants With Active Psoriatic Arthritis After Inadequate Response to One Prior Tumor Necrosis Factor Inhibitor: Week‐24 Results of a Phase 3, Randomized, Placebo‐Controlled Study
Arthritis &Rheumatology, EarlyView.Objective
To evaluate the efficacy and safety of guselkumab, an interleukin‐23p19 subunit inhibitor, in participants with active psoriatic arthritis (PsA) and inadequate response (inadequate efficacy and/or intolerance) to one prior tumor necrosis factor (TNF) inhibitor.Alexis Ogdie, Joseph F. Merola, Philip J. Mease, Christopher T. Ritchlin, Jose U. Scher, Kimberly Parnell Lafferty, Daphne Chan, Soumya D. Chakravarty, Wayne Langholff, Yanli Wang, Jie Shao, Yevgeniy Krol, Alice B. Gottlieb +12 morewiley +1 more sourceEthnic variation in inflammatory profile in tuberculosis [PDF]
, 2013 Distinct phylogenetic lineages of Mycobacterium tuberculosis (MTB) cause disease in patients of particular genetic ancestry, and elicit different patterns of cytokine and chemokine secretion when cultured with human macrophages in vitro.Bothamley, GH, Baker Lucy V., Nikolayevskyy, V, Barker, Richard D., Adrian R. Martineau (136644), Heather J Milburn, Drobniewski, Francis A., Nuamah, RA, Martineau, AR, Timms Peter M., Francis A. Drobniewski (349928), Coussens, Anna K., Griffiths, CJ, Vladyslav Nikolayevskyy, Drobniewski, FA, Bhaw-Rosun, L, Rosamond A. Nuamah (430904), Kamrul Islam (430894), Coussens Anna K., Francis A Drobniewski, Milburn, HJ, Davidson Robert N., Nuamah Rosamond A., Alleyna P Claxton, Charles A Mein, Yasmeen Hanifa, Yasmeen Hanifa (430893), Drobniewski Francis A., Elkington, Paul T., Graham H. Bothamley (430896), Claxton Alleyna P., Graham H Bothamley, Elkington Paul T., Peter M. Timms (430895), Anna K. Coussens (430892), Davidson, Robert N., Vladyslav Nikolayevskyy (349919), Bhaw-Rosun Leena, Milburn, Heather, Martineau, Adrian R., Paul T. Elkington (364501), Packe, Geoffrey E., Mein, Charles A., Young, Douglas B., Geoffrey E Packe, Martineau Adrian R., Islam, Kamrul, Packe, GE, Mathina Darmalingam, Anna K Coussens, Robert N Davidson, Mathina Darmalingam (430899), Timms, Peter M., Rosamond A Nuamah, Hanifa, Yasmeen, Elkington, PT, Lucy V. Baker (430901), Nikolayevskyy, Vladyslav, Bothamley, Graham H., Richard D. Barker (430902), Milburn, Heather J., Leena Bhaw-Rosun (430903), Robert J Wilkinson, Baker, Lucy V., Darmalingam, M, Wilkinson, Robert J., Christopher J Griffiths, Bothamley Graham H., Robert J. Wilkinson (130050), Hanifa Yasmeen, Claxton, Alleyna P., Kamrul Islam, Darmalingam Mathina, Barker, RD, Peter M Timms, Wilkinson Robert J., Griffiths Christopher J., Islam Kamrul, Nuamah, Rosamond A., Hanifa, Y, Packe Geoffrey E., Barker Richard D., Claxton, AP, Alleyna P. Claxton (430897), Robert N. Davidson (364270), Coussens, AK, Timms, PM, Paul T Elkington, Christopher J. Griffiths (430905), Leena Bhaw-Rosun, Davidson, RN, Milburn Heather J., Griffiths, Christopher J., Lucy V Baker, Geoffrey E. Packe (430898), Richard D Barker, Darmalingam, Mathina, Nikolayevskyy Vladyslav, Heather J. Milburn (430900), Mein, CA, Charles A. Mein (46734), Baker, LV, Wilkinson, RJ, Adrian R Martineau, Mein Charles A., Bhaw-Rosun, Leena, Islam, K +106 morecore +1 more sourcePerformance of the MeltPro TB assay as initial test for diagnosis of pulmonary tuberculosis with drug-resistance detection
Molecular Medicine, 2023 Background The MeltPro TB assay (MeltPro) is a molecular rapid diagnostic test designed for detecting resistance to antituberculosis drugs. However, the performance of MeltPro as an initial diagnostic test for simultaneously detecting the presence of ...Zhi-bin Liu, Li-ping Cheng, Hong-qiu Pan, Xiao-cui Wu, Fu-hui Lu, Jie Cao, Lei Wang, Wei Wei, Hong-yu Chen, Wei Sha, Qin Sun +10 moredoaj +1 more sourceCombination Therapy in Participants With Active Psoriatic Arthritis Using Subcutaneous Guselkumab and Golimumab: Week 24 Results From a Phase 2a, Multicenter, Randomized, Double‐Blind, Proof‐of‐Concept Study
Arthritis &Rheumatology, EarlyView.Objective
To assess guselkumab + golimumab combination therapy versus guselkumab monotherapy in participants with active psoriatic arthritis (PsA) and inadequate response to tumor necrosis factor inhibitors (TNFi‐IR). Methods
Adults with active TNFi‐IR PsA (three or more tender/swollen joints) were randomized (2:1) to subcutaneous guselkumab (100 mg) + Jose U. Scher, Iain B. McInnes, Enrique R. Soriano, Joseph F. Merola, Paul Bird, Vinod Chandran, Edaire Cheng, Elena Reynoso, Warner Chen, Maoji Li, Lianne S. Gensler, Philip J. Mease, Christopher T. Ritchlin +12 morewiley +1 more sourceIntegrated Clinical and Proteomic Profiling of CD19 Chimeric Antigen Receptor T Cell Therapy in Progressive Systemic Sclerosis
Arthritis &Rheumatology, EarlyView.Objective
To characterize the clinical, immunologic, and proteomic changes associated with CD19 chimeric antigen receptor T cell therapy in patients with progressive systemic sclerosis (SSc). Methods
Patients with progressive SSc received CD19 chimeric antigen receptor (CAR)‐T cell therapy and were observed longitudinally for safety, clinical efficacy, Chenhan Jia, Wanyi Lin, Zhangyi Zhao, Fenglin Wu, Chaoyu Gu, Yuankai Sun, Zhe Ding, Chang Wei, Xinyu Li, Cuiwei Xie, Peng Xia, Zhen Xia, Xuesong Liu, Shaoying Yang, Chunyan Zhang, Hanlin Yin, Liangjing Lu +16 morewiley +1 more sourceDistribution and transmission of mycobacterium tuberculosis complex lineages among children in peri-urban Kampala, Uganda [PDF]
, 2015 To gain insight into the transmission of tuberculosis (TB) in peri-urban Kampala-Uganda, we performed a household contact study using children as a surrogate for recent transmission of Mycobacterium tuberculosis (MTB).Eddie M. Wampande, Kathleen Eisenach, Mary Nsereko, Wampande, Eddie M., W. Henry Boom, Mayanja, Harriet K., Mupere, Ezekiel, Gagneux, Sebastien, Eisenach, Kathleen, Joloba, Moses L., Moses L. Joloba, Ezekiel Mupere, Nsereko, Mary, Sebastien Gagneux, Harriet K. Mayanja, null null, Devan Jaganath, Boom, W. Henry, Jaganath, Devan, Tuberculosis Research Unit, +19 morecore +1 more source