Results 81 to 90 of about 169,884 (264)

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

Phytotherapy Research, EarlyView.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee, Yu Jin So, Il‐Joo Jo, Ji Yong Jang, Tae Han Yook, Jun Ho Lee, Sung Wook Kim, Kangwook Lee, Soo Jung Park, Gabsik Yang   +9 more
wiley   +1 more source

Vegetating Lupus Vulgaris in a Child

JEADV Clinical Practice, EarlyView.
Viktor Pushkarenko, Yana‐Karina Zovdun, Olga Pushkarenko   +2 more
wiley   +1 more source

Bridging Psychological Stress and Skin Cellular Aging: Flavonoids as a Dual‐Action Therapeutic Strategy

Phytotherapy Research, EarlyView.
ABSTRACT Psychological stress (or simply “stress”) is a major contributor to chronic disease worldwide, affecting 35% of the global population, including younger generations. Furthermore, it plays a significant role in human premature aging; hence, its detrimental effects on people's health compel us to comprehend and control the ways in which ...
Marco Duarte, Sílvia Santos Pedrosa, P. Raaj Khusial, Ana Raquel Madureira   +3 more
wiley   +1 more source

Prognostic Value of a Cardiopulmonary Exercise Testing‐Derived Summed Score in Idiopathic Pulmonary Fibrosis and Connective Tissue Disease‐Associated Interstitial Lung Disease: A Prospective Cohort Study

Respirology, EarlyView.
A cardiopulmonary exercise testing‐derived summed score effectively predicted mortality or lung transplantation risk in newly diagnosed interstitial lung disease. Higher summed scores (2–5) were associated with markedly lower event‐free survival rates.
Yu‐Lin Tsai, Kai‐Ming Chang, Chung‐Shih Chin, Chiann‐Yi Hsu, Yi‐Hsuan Yu, Yuan‐Yang Cheng, Pin‐Kuei Fu   +6 more
wiley   +1 more source

Refractory Lichen Amyloidosis Coexisting With Atopic Dermatitis Responsive to Sequential Janus Kinase Inhibitor Therapy: Upadacitinib Followed by Abrocitinib

The Kaohsiung Journal of Medical Sciences, EarlyView.
Yu‐Ting Tsai, Jui Lan, Shang‐Hung Lin   +2 more
wiley   +1 more source

Diagnostic Accuracy of Cough Frequency Monitors: A Systematic Review and Meta‐Analysis

Respirology, EarlyView.
ABSTRACT Background and Objective International guidelines emphasise the importance of objective cough assessment for evaluating therapeutic efficacy. Cough negatively impacts quality of life and generates high costs for healthcare systems. However, the accuracy of cough frequency monitors remains unclear.
Ana Lara Castro Rodrigues, Larisse Sousa Reis Passafaro, Daniele Oliveira dos Santos, Marcos Gontijo da Silva, Noé Mitterhofer Eiterer Ponce de Leon da Costa, Janne Marques Silveira, Arietta Spinou, Ada Clarice Gastaldi   +7 more
wiley   +1 more source

Efflux pumps positively contribute to rifampin resistance in rpoB mutant Mycobacterium tuberculosis

Annals of Clinical Microbiology and Antimicrobials
Background While several recent studies have documented the importance of efflux pumps as mediators of rifampin (RIF) resistance, it remains uncertain which efflux pumps play major roles in rifampin-resistant Mycobacterium tuberculosis strains harboring ...
Fanrong Meng, Yuanjin Chen, Zeyou Wei, Zhihui Liu, Xiaomin Lai, Jie Lei, Ling Wu, Li Deng, Qi Wang, Yu Yang, Hua Li, Bei Xie, Lan Gong, Qun Niu, Junwen Gao, Nan Wang, Jinxing Hu   +16 more
doaj   +1 more source

Development of a Novel Polyleucine‐Based Immunopotentiator for Subunit Vaccines Against Group A Streptococcus

Small, EarlyView.
Self‐assembling amphiphilic peptide L15K6 is used as a novel immunoadjuvant for the development of a Group A Streptococcus vaccine. Robust antigen‐specific IgG responses are generated and manage to kill isolated strains of Group A Streptococcus. Cellular and bulk RNA sequencing data reveals that L15K6 regulates immune responses potentially through TLR ...
Lantian Lu, Jazmina L. Gonzalez Cruz, Rabina Giri, Yuexiao Zhang, Sahra Bashiri, Leslie C. Domínguez Cadena, Shuhang Li, Zeinab G. Khalil, Waleed M. Hussein, Jingwen Wang, Jolynn Kiong, Xuehan Lu, Jiahui Zhang, Miao Lu, Wenbin Huang, Wei Yang Kong, Ummey Jannatun Nahar, Prashamsa Koirala, Zhong Guo, Patricia Walden, Antje Blumenthal, Jakob Begun, Kirill Alexandrov, Istvan Toth, Rachel J. Stephenson, Mariusz Skwarczynski   +25 more
wiley   +1 more source

Bioequivalence and Safety of Two Amisulpride Formulations in Healthy Chinese Subjects Under Fasting and Fed Conditions: A Randomized, Open‑Label, Single‑Dose, Crossover Study

Drugs in R&D
Background and Objectives Amisulpride is a second-generation antipsychotic drug that selectively binds to D2 and D3 dopaminergic receptors in the limbic system.
Min Wang, Yu Peng, Hegui Yan, Zhixiang Pan, Ronghui Du, Guan Liu   +5 more
doaj   +1 more source

Temporal and Spatial Organization in Collaborative Work by Nurses in an Emergency and Critical Care Center

Symbolic Interaction, EarlyView.
This study describes the work at an emergency and critical care center, focusing on the collaboration of multiple nurses when moving patients from the outpatient department to the ward. This study is an ethnomethodological ethnography based on fieldwork at a hospital and analysis of video data. The patient transport process is temporally organized into
Hiroki Maeda, Yumi Nishimura
wiley   +1 more source