Results 131 to 140 of about 4,197,466 (259)

Tryptophan metabolism: a potential link between the gut microbiota and pulmonary vascular remodeling in pulmonary hypertension

Frontiers in Cellular and Infection Microbiology
Pulmonary hypertension (PH) comprises a group of cardiopulmonary disorders characterized by a sustained increase in pulmonary vascular resistance and pulmonary vascular remodeling, with disease progression potentially leading to right heart failure and ...
Hui Zhang, Hui Zhang, Guangyang Ou, Jian Yi, Zhongyi Huang, Zhongyi Huang, Lijun Gong, Lan Song, Feiying Wang, Aiguo Dai, Aiguo Dai, Aiguo Dai   +11 more
doaj   +1 more source

Basis for the selective reduction of pulmonary vascular resistance in humans during infusion of adenosine

, 1994
The objective of this study was to demonstrate the basis for the selective reduction of pulmonary vascular resistance by intravenous infusion of adenosine.
E. D. Staples, D. B. Utterback, S. E. White, J. A. Hill, L. Belardinelli   +4 more
core   +1 more source

Implantable Systems for Cardiovascular Treatment and Monitoring: Comparative Insights From Intracardiovascular and Extracardiovascular Technologies

Advanced Intelligent Systems, EarlyView.
A unifying device–cardiovascular interface framework is presented to classify implantable cardiovascular technologies as intracardiovascular blood‐contacting systems or extracardiovascular tissue‐only and blood‐handling architectures. Cross‐class comparison across shared semiquantitative criteria, including blood‐contact burden, biomimicry ...
Bergo Nicolò, Semproni Federica, Maselli Martina, Colli Andrea, Cianchetti Matteo, Ciuti Gastone, Stefanini Cesare, Menciassi Arianna   +7 more
wiley   +1 more source

Genetic predisposition to porto‐sinusoidal vascular disorder: A functional genomic‐based, multigenerational family study

Hepatology, EarlyView., 2022
A deleterious variant of FCHSD1 results in mTOR pathway overactivation and may cause porto‐sinusoidal vascular disorder (PSVD). The pedigree of the family demonstrated an autosomal dominant disease with variable expressivity. Whole‐genome sequencing and Sanger sequencing both validated the existence of the FCHSD1 variant and the heterozygosity of c ...
Jingxuan Shan, André Megarbane, Aziz Chouchane, Deepak Karthik, Ramzi Temanni, Atilio Reyes Romero, Huiying Hua, Chun Pan, Xixi Chen, Murugan Subramanian, Chadi Saad, Hamdi Mbarek, Cybel Mehawej, Eliane Chouery, Sirin W. Abuaqel, Alexander Dömling, Sami Remadi, Cesar Yaghi, Pu Li, Lotfi Chouchane   +19 more
wiley   +1 more source

Inhaled nitric oxide and high concentrations of oxygen in pediatrics patients with congenital cardiopathy and pulmonary hypertension: report of five cases

São Paulo Medical Journal
Five patients with ages ranging from 6 months to 3 years were analyzed. All received inhaled nitric oxide (NO - 20 parts per million (ppm) ) and oxygen (0(2) - at a concentration of 90-95%) by means of an oxygen hood. Mean Pulmonary Artery Pressure (MPAP)
Werther Brunow de Carvalho, Antonio Carlos Camargo Carvalho, Gisele Limongeli Gurgueira, Angela Mityo Ikeda, June Ho Lee, Dirceu Rodrigues Almeida   +5 more
doaj   +1 more source

Translational Macrophage Mechano‐Immunotherapy for Next‐Generation Implantable Biomaterials

Advanced NanoBiomed Research, EarlyView.
This review explores how macrophage mechanosensing drives inflammation, fibrosis and foreign body responses to implanted biomaterials. It examines emerging pharmacological strategies to modulate mechanotransduction, alongside biomaterial platforms for localised drug delivery, clinical translation, regulatory considerations and standardised testing ...
Xueying Xu, Ian L. Chin, Richard P. Tan
wiley   +1 more source

Activation of Metal Complexes With Ultrasound Waves for Targeted Anticancer Therapy

Angewandte Chemie International Edition, EarlyView.
Ultrasound enables non‐invasive activation of metal‐based therapeutics deep within tumors. Acoustic cavitation can drive sonodynamic reactive oxygen species generation or mechanochemical metal–ligand bond dissociation, enabling controlled release of bioactive payloads.
Félix Grosjean, Nicolás Montesdeoca, Gilles Berger, Johannes Karges   +3 more
wiley   +1 more source

Rising Use of Reconstructive Cartilage Procedures of the Knee With Persistently Low Surgical Complication Rates Based on the American College of Surgeons National Surgical Quality Improvement Program

Arthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To determine current treatments used for chondral defects of the knee, to analyze complications, and to identify risk factors for adverse events. Methods In this retrospective database study, the American College of Surgeons National Surgery Quality Improvement Program database (2010‐2023) was searched using Current Procedural Terminology codes
Braeden R. Gooch, Grayson M. Talaski, Shahab Yazdanpanah, Charles R. Reiter, Conor N. O’Neill, Omar A. Protzuk, J. Brett Goodloe, Christian Lattermann, Annuziato N. Amendola   +8 more
wiley   +1 more source

Cytokine Pathways Driving Diverse Tissue Pathologies in Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Rheumatoid arthritis (RA) is a complex systemic disorder characterized primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease, such as that of the lung, with potentially devastating clinical consequences. The critical importance of comorbidities,
Aurelie Najm, Lyn D. Ferguson, Iain B. McInnes   +2 more
wiley   +1 more source

Estimation of pulmonary vascular resistance with Doppler diastolic gradients.

, 2008
This study was undertaken to determine the diastolic Doppler echocardiographic correlates of pulmonary vascular resistance calculated on cardiac catheterization in Patients with secondary pulmonary arterial hypertension. Thirty-eight consecutive Patients
Tasneem, Habiba, Atiq, Mehnaz, Aziz, Kalimuddin   +2 more
core