Results 121 to 130 of about 4,197,466 (259)

The results of univariate and multivariate analysis to determine the variables associated with follow-up pulmonary vascular resistance.

open access: yes, 2015
SRC: standardized regression coefficientThe results of univariate and multivariate analysis to determine the variables associated with follow-up pulmonary vascular resistance.
Seiichiro Sakao (515628)   +9 more
core   +1 more source

Ischemic Postconditioning Protects Aged Myocardium Against Ischemia/Reperfusion Injury by Regulating Mitochondrial Dynamics via piR‐4913

open access: yesAdvanced Science, EarlyView.
A tiny RNA tips the scales of cardiac injury in aging. piR‐4913 recruits OGT to Drp1 and drives its O‐GlcNAcylation at Thr604, promoting excessive mitochondrial fission that aggravates ischemia‐reperfusion injury. Ischemic postconditioning silences this pathway to restore mitochondrial balance and protect the aged myocardium, revealing piR‐4913 as a ...
Xiangyu Zhao   +11 more
wiley   +1 more source

Clinicolaboratory characteristics and 1-year survival among group 1 pulmonary hypertension in a university hospital

open access: yesThe Egyptian Journal of Bronchology
Background Pulmonary arterial hypertension is a life-threatening disorder of the pulmonary vascular system that can lead to right-sided heart failure, respiratory failure, and death. Still, more knowledge is needed to understand this complex disease. The
Mostafa K. Ahmed   +4 more
doaj   +1 more source

Pulmonary Vascular Input Impedance in Patients with Atrial Septal Defect [PDF]

open access: yes, 1994
Pulmonary vascular input impedance was measured in adults with artial septal defect (ASD) to examine their pulmonary vessel lesions. Pulmonary vascular input impedance is a measure of the resistance of the pulmonary artery detected in the form of pulse ...
Matsuzaki, Tadaki
core  

Pulmonary vascular resistance after cessation of positive end-expiratory pressure

open access: yes, 1989
This report describes the pulmonary vascular response of infant lamb lung to abrupt cessation of positive end-expiratory pressure (PEEP) during volume-regulated continuous positive-pressure breathing (CPPB).
S. Venkataraman   +3 more
core   +1 more source

Lactate Drives Pathological Browning of White Adipose Tissue to Aggravate Sepsis‐Associated Metabolic Disorders in a GPR81‐Dependent Manner

open access: yesAdvanced Science, EarlyView.
Sepsis‐triggered lactate accumulation induces pathological white adipose tissue browning. Lactate activates adipocyte GPR81 to sequentially upregulate CTRP6‐p38 signalling and UCP1 expression. This cascade exacerbates sepsis‐associated metabolic disorders.
Chunliang Zheng   +4 more
wiley   +1 more source

Abnormal Renal Resistive Index in Patients with Mild-to-moderate Chronic Obstructive Pulmonary Disease

open access: yes, 2014
Background: Arterial rigidity and endothelial dysfunction are systemic manifestations of chronic obstructive pulmonary disease (COPD). The decrease in renal vascular resistance in order to adapt the increase in glomerular filtration rate after oral ...
Chen, Cheng-Yu;Hsu, Ta-Wei;Mao, Simon J. T.;Chang, Shih-Chieh;Yang, Pan-Chyr;Lee, Yu-Chin;Yang, Kuang-Yao   +1 more
core   +1 more source

Stroke‐Heart Syndrome: Mechanisms, Temporal Phenotypes, and Diagnostic Reasoning

open access: yesAdvanced Science, EarlyView.
Stroke‐heart syndrome describes new or worsened cardiac abnormalities after acute stroke. This Review defines its clinical boundaries, traces autonomic, inflammatory, endothelial, and supply‐demand mechanisms across time, and proposes provisional phenotypes that integrate lesion location, premorbid cardiac substrate, serial biomarkers ...
Fa Lin   +13 more
wiley   +1 more source

Comparison of the effect of inhaled anaesthetic with intravenous anaesthetic on pulmonary vascular resistance measurement during cardiac catheterisation

open access: yes, 2015
Background: Children with pulmonary hypertension routinely undergo pulmonary vascular resistance studies to assess the disease severity and vasodilator responsiveness.
Giesen, Leonie A.   +2 more
core   +1 more source

TIPIN Couples Epigenetic Rewiring to EGFR Stabilization and Lenvatinib Resistance in Liver Cancer

open access: yesAdvanced Science, EarlyView.
DNA hypomethylation elevates TIPIN expression in liver cancer. TIPIN competes with E3 ligase c‐Cbl for the EGFR intracellular domain, inhibiting EGFR ubiquitination and lysosomal degradation to sustain oncogenic EGFR‐ ERK signaling. High TIPIN confers lenvatinib resistance, while TIPIN depletion restores drug sensitivity in liver cancer. ABSTRACT Aims:
Xing Jia   +15 more
wiley   +1 more source

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