Results 31 to 40 of about 440,279 (349)
Pulmonary Circulation, 2020 Pulmonary Hypertension due to left heart disease is the most common type of Pulmonary Hypertension. Morbidity and mortality significantly increase once Pulmonary Hypertension is present.
Galo M. Sanchez Palacios +2 more
doaj +1 more source
Clinical Case Reports, 2021 Central principles are interdisciplinary teamwork and keeping the ratio between pulmonary vascular resistance (PVR) and systemic vascular resistance (SVR) balanced to avoid vicious circle with right heart failure and hypoxia.
Raphael Porsche +4 more
doaj +1 more source
Pulmonary Circulation, 2020 While it is well established that the haemodynamic cause of hypoxic pulmonary hypertension is increased pulmonary vascular resistance, the molecular pathogenesis of the increased resistance remains incompletely understood. Macrophage migration inhibitory
Lili Li +7 more
doaj +1 more source
Mitigation of Radiation Induced Pulmonary Vascular Injury by Delayed Treatment with Captopril [PDF]
, 2012 Background and Objective: A single dose of 10 Gy radiation to the thorax of rats results in decreased total lung angiotensin-converting enzyme (ACE) activity, pulmonary artery distensibility and distal vascular density while increasing pulmonary ...
Fish, Brian L. +5 more
core +2 more sources
Journal of Cardiovascular Magnetic Resonance, 2017 BackgroundQuantification of cardiac output and pulmonary vascular resistance (PVR) are critical components of invasive hemodynamic assessment, and can be measured concurrently with pressures using phase contrast CMR flow during real-time CMR guided ...
T. Rogers +15 more
semanticscholar +1 more source
Pulmonary arterial hypertension with below threshold pulmonary vascular resistance [PDF]
European Respiratory Journal, 2020 Pulmonary vascular resistance (PVR) >3 Wood units is a criterion of the haemodynamic definition of pulmonary arterial hypertension (PAH). However, this cut-off is conservative and arbitrarily defined. Data is lacking on the natural history, response to therapy and survival of patients diagnosed with precapillary pulmonary hypertension (PH) with mild
Seshika Ratwatte +16 more
openaire +3 more sources
Treatment of exercise pulmonary hypertension improves pulmonary vascular distensibility
Pulmonary Circulation, 2018 Exercise pulmonary hypertension (ePH) is an underappreciated form of exertional limitation. Despite normal resting pulmonary artery pressures, patients with ePH demonstrate early pulmonary vascular changes with reduced pulmonary arterial compliance (PAC)
William D. Wallace +3 more
doaj +1 more source
Tetrahydrobiopterin analogues with NO-dependent pulmonary vasodilator properties [PDF]
, 2011 Reduced NO levels due to the deficiency of tetrahydrobiopterin (BH4) contribute to impaired vasodilation in pulmonary hypertension Due to the chemically unstable nature of BH4 it was hypothesised that oxidatively stable analogues of BR, would be able to ...
Gibson, Colin +4 more
core +1 more source
Pulmonary Haemodynamics in Sickle Cell Disease Are Driven Predominantly by a High-Output State Rather Than Elevated Pulmonary Vascular Resistance: A Prospective 3-Dimensional Echocardiography/Doppler Study. [PDF]
PLoS ONE, 2015 Patients with sickle cell disease have significant morbidity and mortality. Pulmonary hypertension is suggested to be an important contributor but its nature and severity in these patients and how best to non-invasively assess it are controversial.
Sitali Mushemi-Blake +9 more
doaj +1 more source
Smooth muscle myosin inhibition: a novel therapeutic approach for pulmonary hypertension. [PDF]
PLoS ONE, 2012 Pulmonary hypertension remains a major clinical problem despite current therapies. In this study, we examine for the first time a novel pharmacological target, smooth muscle myosin, and determine if the smooth muscle myosin inhibitor, CK-2019165 (CK-165)
David Ho +9 more
doaj +1 more source