Results 231 to 240 of about 561,418 (271)

The Role of Vasculature Engineering in Dental Pulp Regeneration

Journal of Endodontics, 2017
Creating an optimal microenvironment that supports angiogenesis, cell-cell cross talk, cell migration, and differentiation is crucial for pulp/dentin regeneration. It was shown that dental stem cells being seeded onto a scaffold and transplanted in vivo could give rise to a new tissue similar to that of the native pulp. However, the unique structure of
Zhang, C, Dissanayaka, WL
openaire   +4 more sources

Dentine–Pulp Complex Regeneration

2021
Root canal treatments are common procedures in dentistry. In the USA, each year more than 20 million teeth receive root canal treatment, with overall cost over more than US$2 billion. However, in many clinical situations, the decision to perform pulp removal and endodontic treatment is justified only by the absence of therapeutic tools that are able to
Ove A. Peters, Avina Paranjpe, Alexis Gaudin   +2 more
openaire   +1 more source

Dentin-Pulp Complex Regeneration

2020
This chapter focuses on presenting new strategies for local regeneration therapy of the dentin-pulp complex; such a process is mediated by odontoblast and relates to preservation of pulp vitality, and clinical management of deep caries, necrotic pulp with apical periodontitis necrotic and immature permanent teeth. It helps the reader understand factors
Amaury Pozos-Guillén, Héctor Flores
openaire   +1 more source

Regenerating the Dental Pulp–Scaffold Materials and Approaches

Dental Clinics of North America, 2022
Novel technologies and platforms have allowed significant breakthroughs in dental pulp tissue engineering. The development of injectable scaffolds that can be combined with stem cells, growth factors, or other bioactive compounds has enabled the regeneration of functional dental pulps able to secrete dentin in preclinical and clinical studies ...
Diana Gabriela, Soares, Vinicius, Rosa
openaire   +2 more sources

Transplantation of Dental Pulp Stem Cells and Platelet-rich Plasma for Pulp Regeneration

Journal of Endodontics, 2012
The loss of dental pulp may weaken teeth, rendering them susceptible to reinfection, fracture, and subsequent tooth loss. Therefore, regeneration of pulp is considered an ideal treatment to preserve teeth. The aim of this study was to explore the capacity of dental pulp stem cells (DPSCs) and platelet-rich plasma (PRP) to regenerate dental pulp in ...
George T-J Huang, Waruna Lakmal Dissanayaka, Xiaofei Zhu   +2 more
exaly   +6 more sources

Dentin-Pulp Complex Regeneration

Advances in Dental Research, 2011
Dentistry is entering an exciting era in which many of the advances in biotechnology offer opportunities for exploitation in novel and more effective therapies. Pulp healing is complex and dependent on the extent of injury, among many other factors. Many of the molecular and cellular processes involved in these healing events recapitulate developmental
S R J, Simon, A, Berdal, P R, Cooper, P J, Lumley, P L, Tomson, A J, Smith   +5 more
openaire   +2 more sources

Pulp regeneration: follow the guide

L' Orthodontie francaise, 2023
What if we changed our point of view? What if we approached endodontics from a biological perspective rather than a mechanistic one? What if, in the case of pulpal tissue necrosis, we were to consider an alternative to apexification therapies? Is pulp tissue regeneration now possible?Regenerative endodontic therapy (RET) aims to regenerate the pulp ...
Magali, Hernandez, Raphaël, Hainot
openaire   +1 more source

Induced Migration of Dental Pulp Stem Cells for in vivo Pulp Regeneration

Journal of Dental Research, 2011
Dental pulp has intrinsic capacity for self-repair. However, it is not clear whether dental pulp cells can be recruited endogenously for regenerating pulp tissues, including mineralizing into dentin. This work is based on a hypothesis that dental pulp stem/progenitor cells can be induced to migrate by chemotactic cytokines and act as endogenous cell ...
T, Suzuki, C H, Lee, M, Chen, W, Zhao, S Y, Fu, J J, Qi, G, Chotkowski, S B, Eisig, A, Wong, J J, Mao   +9 more
openaire   +2 more sources

Acellular dental pulp and allogeneic cells for strategic pulp regeneration

Tissue and Cell
Regenerative endodontics aims to restore the damaged pulp-dentin complex, moving beyond revascularization to functional tissue regeneration, which includes innervation. While dental pulp stem cells (DPSCs) have been widely studied, their clinical application is hindered by low cell yield and reduced regenerative capacity in late passages.
Nora Sakina Mohd Noor, Xin-Jieh Lam, Ghee-Seong Lim, May-Nak Lau, Mang-Chek Wey, Abilashini Rajendran, Khong-Lek Then, Nazmul Haque, Noor Hayaty Abu Kasim, Vijayendran Govindasamy, Noor Hayati Azami   +10 more
openaire   +2 more sources

Pulp Regeneration by 3-dimensional Dental Pulp Stem Cell Constructs

Journal of Dental Research, 2018
Dental pulp regeneration therapy for the pulpless tooth has attracted recent attention, and clinical trial studies are underway with the tissue engineering approach. However, there remain many concerns, including the extended period for regenerating the dental pulp. In addition, the use of scaffolds increases the risk of inflammation and infection.
Y. Itoh, J.I. Sasaki, M. Hashimoto, C. Katata, M. Hayashi, S. Imazato   +5 more
openaire   +2 more sources