Results 31 to 40 of about 7,411,244 (251)

Pulsed Field Ablation for the Interventional Treatment of Cardiac Arrhythmias

, 2022
International audiencePulsed field ablation is a recent addition to the techniques used to ablate pathological arrhythmic circuits. Despite its recent introduction in the clinical field, pulsed field ablation exploits the well-known phenomenon of ...
Caluori, Guido, Poignard, Clair, Collin, Annabelle, Jais, Pierre   +3 more
core   +1 more source

Impact of Left Atrial Posterior Wall Ablation During Pulsed-Field Ablation for Persistent Atrial Fibrillation. [PDF]

BACKGROUND Pulmonary vein isolation (PVI) alone is insufficient to treat many patients with persistent atrial fibrillation (PersAF). Adjunctive left atrial posterior wall (LAPW) ablation with thermal technologies has revealed lack of efficacy, perhaps
Metzner, Andreas, Wakili, Reza, Sommer, Philipp, Fueting, Anna, Deneke, Tom, Gunawardene, Melanie, Ouss, Alexandre, Funasako, Moritoshi, Rollin, Anne, Chaumont, Corentin, Turagam, Mohit K., Scherr, Daniel, Reddy, Vivek Y., Reinsch, Nico, Willems, Stephan, Bohnen, Jan-Eric, Boveda, Serge, Reddy, Vivek Y, Hansen , Jim, Mulder, Bart A.; id_orcid, Hansen, Jim, Reichlin, Tobias, Anic, Ante, Fink, Thomas, Roten, Laurent, Derval, Nicolas, Jais, Pierre, van der Voort, Pepijn, Heeger, Christian Hendrik, Manninger, Martin, Sultan, Arian, Kueffer, Thomas, Maury, Philippe, Turagam, Mohit K, Vijgen, Johan, Peichl, Petr, Mulder, Bart A., Bohnen, Jan Eric, Mulder, Bart A, Neven , Kars, Nentwich, Karin, Kautzner, Josef, Willems , Stephan, Anselme, Frederic, Neven, Kars, Chun, Julian, Neuzil, Petr, Petru, Jan, Blaauw, Yuri, Jurisic, Zrinka, Lehrmann, Heiko, Arentz, Thomas, Schmidt, Boris, Koopman, Pieter, Steven, Daniel, Adelino, Raquel, Lemoine, Marc D., Tilz, Roland, Heeger, Christian-Hendrik, Füting, Anna, Lemoine, Marc D, Ruwald, Martin   +61 more
core   +3 more sources

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Pulsed-Field Ablation Using a Novel Ablation-Mapping Integrated System for Pulmonary Vein Isolation—A Preliminary Animal Study

Journal of Cardiovascular Development and Disease, 2022
Objective: The purpose of this study is to evaluate the preliminary safety and effect of a pulsed electric field (PEF) ablation system. Methods: The pulmonary veins (PVs) and superior vena cava (SVC) were isolated with the pulsed field ablation (PFA ...
Zhihong Zhao, Yonggang Chen, Bin Wu, Gaodong Qiu, Liangjie Hong, Xinhua Chen, Xingwei Zhang   +6 more
doaj   +1 more source

Update on CO2 Laser Ablation of Polyoxymethylene [PDF]

, 2010
Polyoxymethylene (POM) propellants have been studied since the 1970's, and perhaps represent the most promising match of a propellant to the CO2 laser for laser propulsion studies.
Sinko, John Elihu, Eckel, Hans-Albert, Sasoh, Akihiro, Scharring, Stefan, Ogita, Naoya, Röser, Hans-Peter   +5 more
core  

High-power-short-duration-radiofrequency-, cryoballoon-, and pulsed-field-ablation: a prospective clinical study

BMC Cardiovascular Disorders
Background Pulmonary vein isolation aims to reduce the burden of atrial fibrillation leading to symptom alleviation and improvement in quality of life.
Daniel Robinson, Hanna Seiler, Stephan Valenta, Plamen Kochev, Jakob Eichhorn, Jonas Bodanowitz, Anton Khvan, Annegret Werner, Chrisia Arnold, Christian Ewertsen, Sebastian Feickert, Burkert Pieske, Hüseyin Ince, Jasmin Ortak   +13 more
doaj   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Nanosecond ablation of alumina with an ytterbium fibre-laser: experimental study, topography and damage evaluation [PDF]

, 2014
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Programa de Pós-Graduação em Ciência e Engenharia de Materiais, Florianópolis, 2014.Abstract : The use of advanced ceramics has been limited by the high machining costs, with grinding and ...
Gomes, Diego Ribas
core  

Pulsed-field ablation for repeat procedures after failed prior thermal ablation for atrial fibrillation. [PDF]

BACKGROUND Pulsed-field ablation (PFA) is a novel nonthermal ablation technology. Its potential value for repeat procedures after unsuccessful thermal ablation for atrial fibrillation has not been assessed.
Kueffer, Thomas, Galuszka, Oskar, Roten, Laurent, Kozhuharov, Nikola, Reichlin, Tobias, Tanner, Hildegard, Haeberlin, Andreas, Maurhofer, Jens, Thalmann, Gregor, Servatius, Helge, Madaffari, Antonio, Noti, Fabian   +11 more
core   +2 more sources

Biophysics and Clinical Effectiveness of Irreversible Electroporation for Catheter Ablation of Atrial Fibrillation

Journal of Cardiovascular Development and Disease
Understanding the biophysics of electroporation—the mechanism by which pulsed electric fields achieve tissue ablation—is essential for advancing this emerging technology.
Anna-Sophie Eberl, Gernot Plank, Martin Manninger, Ursula Rohrer, Laura Stix, Stefan Kurath-Koller, Andreas Zirlik, Daniel Scherr   +7 more
doaj   +1 more source