Results 41 to 50 of about 7,731,937 (294)

Pulsed Field Ablation for the Interventional Treatment of Cardiac Arrhythmias

, 2022
International audiencePulsed field ablation is a recent addition to the techniques used to ablate pathological arrhythmic circuits. Despite its recent introduction in the clinical field, pulsed field ablation exploits the well-known phenomenon of ...
Caluori, Guido, Poignard, Clair, Collin, Annabelle, Jais, Pierre   +3 more
core   +1 more source

Using fluorescence fluctuation spectroscopy to quantify molecular dynamics within cells

FEBS Open Bio, EarlyView.
Microscopy techniques like fluorescence correlation spectroscopy (FCS) and number and brightness analysis (N&B) allow to quantify concentrations, diffusion rates, and oligomerization of fluorescently labeled molecules in the living cell. In this protocol the principles of how to set up these types of experiments are described including calibration ...
Mark A. Hink
wiley   +1 more source

Efficacy and safety of novel pulsed field ablation (PFA) technique for atrial fibrillation: A systematic review and meta‐analysis

Health Science Reports, 2023
Background and Aim Pulse field ablation (PFA) has emerged as a safe alternative to other catheter ablation energy sources for patients. Although early results are encouraging, secondary data about outcomes are lacking.
Nour Shaheen, Ahmed Shaheen, Abdelraouf Ramadan, Abdulqadir J. Nashwan   +3 more
doaj   +1 more source

Feasibility Study on Atrial Fibrillation Ablation with Pulsed Field Ablation and concomitant Occlusion of the Left Atrial Appendage. [PDF]

BACKGROUND AND AIMS Atrial fibrillation (AF) ablation and left atrial appendage occlusion (LAAO) are increasingly performed as individual procedures. Pulsed field ablation (PFA) has significantly reduced procedure duration and may be advantageous for ...
Kueffer, Thomas, Siontis, Georgios, Brugger, Nicolas, Beney, Jennifer, Galea, Roberto, Roten, Laurent, Räber, Lorenz, Reichlin, Tobias, Gräni, Christoph   +8 more
core   +2 more sources

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

Comparison of ablation procedures: Cryoablation versus pulsed field ablation

, 2023
Das Ziel dieser Arbeit besteht darin, einen Studienvergleich von klinischen Ergebnissen innerhalb von 12 Monaten bei einer Behandlung von Vorhofflimmern mittels Kryoablation und gepulster Feldablation durchzuführen.
Friedrich, Lisa
core  

Validation of a multipolar pulsed-field ablation catheter for endpoint assessment in pulmonary vein isolation procedures.

, 2022
AIMS To validate the performance of a multipolar pulsed-field ablation (PFA) catheter compared to a standard pentaspline 3D-mapping catheter for endpoint assessment of pulmonary vein isolation (PVI).
Baldinger, Samuel H, Reichlin, Tobias, Tanner, Hildegard, Asatryan, Babken, Servatius, Helge, Madaffari, Antonio, Noti, Fabian, Kueffer, Thomas, Franzeck, Florian, Roten, Laurent, Haeberlin, Andreas, Mühl, Aline, Thalmann, Gregor, Seiler, Jens, Franzeck, Florian Markus, Häberlin, Andreas David Heinrich, Baldinger, Samuel Hannes, Servatius, Helge Simon, Reichlin, Tobias Roman, Küffer, Thomas, Florian Franzeck, Fabian Noti, Tobias Reichlin, Jens Seiler, Aline Mühl, Andreas Haeberlin, Samuel H Baldinger, Antonio Madaffari, Hildegard Tanner, Gregor Thalmann, Laurent Roten, Thomas Kueffer, Babken Asatryan, Helge Servatius   +33 more
core   +1 more source

T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ± 
Sarah J. Wright, Scotty G. McKay, Jean Ramos Bou, Fen Bao, Vivian B. Truong, Chenyang Li, Li Jiang, Anza B. Memon, E. Mark Haacke, Yulin Ge, Yongsheng Chen   +10 more
wiley   +1 more source

Potential Application of Pulsed Field Ablation in Ventricular Arrhythmias

Medicina, 2023
Pulsed field ablation (PFA) is a new ablative method for the therapy of arrhythmia. Recent preclinical and clinical studies have already demonstrated the feasibility and safety of PFA for the treatment of atrial fibrillation (AF).
Jie Qiu, Meiyan Dai, Yang Bai, Guangzhi Chen   +3 more
doaj   +1 more source

Cardiac selectivity in pulsed field ablation

Current Opinion in Cardiology
Purpose of review This review examines the selective cardiac injury induced by pulsed electric fields during atrial fibrillation ablation. It consolidates findings from both preclinical and clinical studies on cardiac selectivity and explores the potential mechanisms behind this selectivity ...
Meng, Fanchao, Jin, Shuqi, Liu, Nian
openaire   +2 more sources