Results 11 to 20 of about 123,460 (289)
Pharmacologically blocking p53-dependent apoptosis protects intestinal stem cells and mice from radiation. [PDF]
, 2015 Exposure to high levels of ionizing radiation (IR) leads to debilitating and dose-limiting gastrointestinal (GI) toxicity. Using three-dimensional mouse crypt culture, we demonstrated that p53 target PUMA mediates radiation-induced apoptosis via a cell ...
Cramer, Julie M +14 more
core +2 more sources
PUMA Cooperates with p21 to Regulate Mammary Epithelial Morphogenesis and Epithelial-To-Mesenchymal Transition. [PDF]
PLoS ONE, 2013 Lumen formation is essential for mammary morphogenesis and requires proliferative suppression and apoptotic clearance of the inner cells within developing acini.
Yanhong Zhang +3 more
doaj +1 more source
Pyrrolyl Squaraines–Fifty Golden Years
Metals, 2015 Pyrrolyl squaraines, both dyes and polymers, were first reported in 1965 and since then a fascinating body of work has been produced investigating the chemistry of these interesting molecules.
Daniel E. Lynch
doaj +1 more source
Pharmacology Research & Perspectives, 2019 Diarrhea is one of the most commonly reported adverse effect of hemotherapy and targeted cancer therapies, such as tyrosine kinase inhibitors (TKI), which often significantly impact patient quality of life, morbidity, and mortality. Neratinib is an oral,
Taras Lysyy +4 more
doaj +1 more source
Comments on Lynch. Pyrrolyl Squaraines—Fifty Golden Years. Metals 2015, 5, 1349–1370
Metals, 2015 In addition to the papers referenced in the main article [1]; [...]
Daniel E. Lynch
doaj +1 more source
Jaguarundi (Puma yagouaroundi) predation by puma (Puma concolor) in the Brazilian Atlantic Forest [PDF]
Biota Neotropica, 2018 Abstract The jaguarundi (Puma yagouaroundi) is the second most widespread carnivore of the Americas, and considered a threatened species in Brazil. However, most of its ecology is unknown, and few information is available about species that may act as its predator.
Magioli, Marcelo +1 more
openaire +2 more sources
Factors Governing Risk of Cougar Attacks on Humans
Human-Wildlife Interactions, 2017 Since the 1980s wildlife managers in the United States and Canada have expressed increasing concern about the physical threat posed by cougars (Puma concolor) to humans.
David Mattson +2 more
doaj +1 more source
PLoS ONE, 2013 HER2 is overexpressed in 15-20% of breast cancers. HER2 overexpression is known to reduce apoptosis but the underlying mechanisms for this association remain unclear.
Richard L Carpenter +3 more
doaj +1 more source
Carnivore-Livestock Conflicts in Chile: Evidence and Methods for Mitigation
Human-Wildlife Interactions, 2019 Human population growth and habitat loss have exacerbated human–wildlife conflicts worldwide. We explored trends in human–wildlife conflicts (HWCs) in Chile using scientific and official reports to identify areas and species with higher risk of conflicts
Valeska Rodriguez +4 more
doaj +1 more source
The Oncologist, EarlyView., 2021 Abstract Background LIBRETTO‐001 is an ongoing, global, open‐label, phase I/II study of selpercatinib in patients with advanced or metastatic solid tumors. We report interim patient‐reported outcomes in patients with RET fusion–positive non‐small cell lung cancer (NSCLC).
Anna Minchom +11 more
wiley +1 more source