Results 21 to 30 of about 27,668 (261)
Chronic inflammation evoked by pathogenic stimulus during carcinogenesis
4 open, 2019 A pathogenic (biological or chemical) stimulus is the earliest information received by a cell that can result in the disruption of homeostasis with consequent development of disease.
Brücher Björn L.D.M., Jamall Ijaz S.
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Mammalogy Notes, 2017 El 19 de marzo de 2016 a las 14h50 observamos un Puma en un parche de bosque pequeño (5,2 ha) en el distrito de Santiago, San Ramón, Provincia de Alajuela, Costa Rica (10,057109° N, -84,492416° W; Figura 2).
Brayan Heiner Morera-Chacón +1 more
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Journal of Cell Biology, 2009 The commitment to programmed cell death via apoptosis is largely made upon activation of the proapoptotic mitochondrial proteins Bax or Bak. In this issue, Gallenne et al. (Gallenne, C., F. Gautier, L. Oliver, E. Hervouet, B. Noël, J.A. Hickman, O. Geneste, P.-F. Cartron, F.M. Vallette, S. Manon, and P. Juin. 2009. J. Cell Biol.
openaire +2 more sources
Frontiers in MicrobiologyEssential oils (EOs) have long been studied for their antimicrobial properties, yet most investigations rely on simplistic models, limited strain panels, and anecdotal interpretations—failing to meet the standards expected of modern anti-infective agents.
Malwina Brożyna +6 more
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PLoS ONE, 2013 HER2 is overexpressed in 15-20% of breast cancers. HER2 overexpression is known to reduce apoptosis but the underlying mechanisms for this association remain unclear.
Richard L Carpenter +3 more
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E2F-1 induces melanoma cell apoptosis via PUMA up-regulation and Bax translocation
BMC Cancer, 2007 Background PUMA is a pro-apoptotic Bcl-2 family member that has been shown to be involved in apoptosis in many cell types. We sought to ascertain whether induction of PUMA plays a crucial role in E2F-1-induced apoptosis in melanoma cells.
Zhou H Sam +5 more
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iNOS/NO is required for IRF1 activation in response to liver ischemia-reperfusion in mice
Molecular Medicine, 2020 Background Ischemia and reperfusion (I/R) induces cytokines, and up-regulates inducible nitric oxide synthase (iNOS), interferon regulatory factor-1(IRF1) and p53 up-regulated modulator of apoptosis (PUMA), which contribute to cell death and tissue ...
Qiang Du +7 more
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Regulation of PUMA induced by mechanical stress in rat cardiomyocytes
Journal of Biomedical Science, 2012 Background PUMA (p53-up-regulated modulator of apoptosis), an apoptosis regulated gene, increased during endoplasmic reticulum stress. However, the expression of PUMA in cardiomyocytes under mechanical stress is little known.
Cheng Wen-Pin +3 more
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Proliferative and Survival Effects of PUMA Promote Angiogenesis
Cell Reports, 2012 The p53 upregulated modulator of apoptosis (PUMA) is known as an essential apoptosis inducer. Here, we report the seemingly paradoxical finding that PUMA is a proangiogenic factor critically required for the proliferation and survival of vascular and ...
Fan Zhang +19 more
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Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source