Results 41 to 50 of about 2,761 (165)

Alterations in Metabolites Associated With Umbilical Cord Blood in Monozygotic Twins Discordant for Congenital Heart Disease. [PDF]

open access: yesPediatr Discov
This study found that the metabolomic signature of umbilical venous cord blood in congenital heart disease (CHD) differs from that of healthy monozygotic (MZ) co‐twins. Dysregulation of metabolic pathways like glucose, lipid, and amino acid metabolism, along with altered metabolites, helps understand CHD predisposition.
Xiang F   +6 more
europepmc   +2 more sources

Evaluation of the In Vitro Oral Wound Healing Effects of Pomegranate (Punica granatum) Rind Extract and Punicalagin, in Combination with Zn (II)

open access: yesBiomolecules, 2020
Pomegranate (Punica granatum) is a well-established folklore medicine, demonstrating benefits in treating numerous conditions partly due to its antimicrobial and anti-inflammatory properties. Such desirable medicinal capabilities are attributed to a high
Vildan Celiksoy   +4 more
doaj   +1 more source

Punicalagin effect on total sleep deprivation memory deficit in male Wistar rats [PDF]

open access: yesJournal of Integrative Neuroscience, 2021
Sleep deprivation has deteriorating effects on cognitive functions and activation of brain inflammation mechanisms has been reported by some studies following total sleep deprivation.
Mohammad Nasehi   +3 more
doaj   +1 more source

Punicalagin Regulates Key Processes Associated with Atherosclerosis in THP-1 Cellular Model

open access: yesPharmaceuticals, 2020
Atherosclerosis may lead to cardiovascular diseases (CVD), which are the primary cause of death globally. In addition to conventional therapeutics for CVD, use of nutraceuticals that prevents cholesterol deposition, reduce existing plaques and hence anti-
Sanaa Almowallad   +5 more
doaj   +1 more source

Punicalagin Ameliorates Lupus Nephritis via Inhibition of PAR2 [PDF]

open access: yesInternational Journal of Molecular Sciences, 2020
Lupus nephritis (LN) is the most frequent phenotype in patients with systemic lupus erythematosus (SLE) and has a high rate of progression to end-stage renal disease, in spite of intensive treatment and maintenance therapies. Recent evidence suggests that protease-activated receptor-2 (PAR2) is a therapeutic target for glomerulonephritis. In this study,
Yohan Seo   +10 more
openaire   +3 more sources

Polyphenol Diversity and Antioxidant Activity of European Cistus creticus L. (Cistaceae) Compared to Six Further, Partly Sympatric Cistus Species

open access: yesPlants, 2021
This investigation focused on the qualitative and quantitative composition of polyphenolic compounds of Mediterranean northern shore Cistus creticus and six further, partly sympatric Cistus species (C. albidus, C. crispus, C. ladanifer, C. monspeliensis,
Brigitte Lukas   +5 more
doaj   +1 more source

An in vitro antiviral evaluation of punicalagin toward influenza A virus

open access: yes, 2022
Abstract Background: Influenza complications are mild to serious, and can cause death in some cases. A great deal of attention has been paid in recent years to the development and use of new antiviral compounds for drug resistance in certain strains of the influenza virus and the clinical implications.
Fatemeh Javadi-Farsani   +4 more
openaire   +3 more sources

Production of a Fungal Punicalagin-Degrading Enzyme by Solid-State Fermentation: Studies of Purification and Characterization

open access: yesFoods, 2023
The present work describes the purification of an enzyme capable of degrading punicalagin. The enzyme was produced by Aspergillus niger GH1 by solid-state fermentation, and the enzyme production was induced by using ellagitannins as the sole carbon ...
Pedro Aguilar-Zárate   +7 more
doaj   +1 more source

Macrophage-Targeted Punicalagin Nanoengineering to Alleviate Methotrexate-Induced Neutropenia: A Molecular Docking, DFT, and MD Simulation Analysis

open access: yesMolecules, 2022
Punicalagin is the most bioactive pomegranate polyphenol with high antioxidant and free-radical scavenging activity and can potentially cure different ailments related to the cardiovascular system.
Ritu Karwasra   +6 more
doaj   +1 more source

Punicalagin: a monomer with anti-Eimeria tenella effect from fruit peel of Punica granatum L.

open access: yesPoultry Science, 2022
: Poultry production was long plagued by coccidiosis, and the development of alternative therapies will make practical sense. In this work, 2 battery experiments were designed.
Yunqiao Yang   +6 more
doaj   +1 more source

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