Punicalagin suppresses methicillin resistance of Staphylococcus aureus to oxacillin
Journal of Pharmacological Sciences, 2018 Methicillin-resistant Staphylococcus aureus (MRSA) is an important human pathogen that is cross-resistant to most β-lactam antibiotics. We investigated whether oxacillin, which is a β-lactam antibiotic, alone or in combination with punicalagin can affect
Ok-Hwa Kang +2 more
exaly +5 more sources
Antibiofilm effects of punicalagin against Staphylococcus aureus in vitro
Frontiers in Microbiology, 2023 Staphylococcus aureus is a common foodborne pathogen which can form biofilms to help them resist to antimicrobials. It brings great harm to human health. Punicalagin has good antimicrobial activities against S. aureus, but its effect on biofilm formation
Yunfeng Xu +7 more
doaj +3 more sources
Punicalagin, a pomegranate compound, induces apoptosis and autophagy in acute leukemia [PDF]
PeerJ, 2021 Background Punicalagin is the major phenolic compound found in pomegranate peels. It has several reported medical benefits, including antioxidant, anti-inflammatory, and anticancer properties.
Paweena Subkorn +3 more
doaj +4 more sources
Current Issues in Molecular Biology, 2022 Atherosclerosis is an important cause of cardiovascular disorders worldwide. Natural botanical drugs have attracted attention due to their antioxidant, anti-inflammatory, and antiatherogenic properties in the treatment of atherosclerosis.
Etimad Huwait +5 more
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Punicalagin Enhances Autophagy Through Sirtuin 1/FoxO3a Axis to Inhibit Intracellular Mycobacterium Abscessus Infection [PDF]
Advanced ScienceMycobacterium abscessus (MAB) is an increasingly recognized rapidly growing nontuberculous mycobacterial pathogen whose infection is particularly challenging to treat due to its antibiotic resistance and persistence, necessitating the exploration of ...
Kefan Bi +4 more
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A Systematic Study of the Hepatic–Intestinal First-Pass Effect and Excretion Pathways of Punicalagin Based on UPLC-MS/MS [PDF]
MoleculesPunicalagin, the major polyphenol in pomegranate peel, shows broad bioactivity but suffers from poor oral bioavailability. Whether hepatic or intestinal first-pass processes dominate this limitation remains unresolved. We developed a quantitative UPLC-MS/
Zixin Chen +3 more
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Integrated Phenotypic and Transcriptomic Analyses Unveil the Antibacterial Mechanism of Punicalagin Against Methicillin-Resistant Staphylococcus aureus (MRSA) [PDF]
FoodsThe growing emergence of multidrug-resistant bacterial pathogens drives the need for new antibacterial agents. Punicalagin exhibits efficacy against methicillin-resistant Staphylococcus aureus (MRSA), but its specific antibacterial mechanisms remain ...
Yiming Wang +7 more
doaj +2 more sources
Exploring Punicalagin Potential Against Cancers: A Comprehensive Review [PDF]
Food Science and NutritionABSTRACTPunicalagin, being a bioactive polyphenol, has gained significant interest owing to its potential anticancer effects. Researchers are studying punicalagin to determine its ability to inhibit cancer cell proliferation. This paper focuses on highlighting the therapeutic potential of punicalagin against tumors and cancers.
Tadesse Fenta
exaly +4 more sources
Bioactive potential of punicalagin: A comprehensive review
Applied Food ResearchPomegranates comprise bioactive components including polyphenols, tannins, and anthocyanins, which have demonstrated beneficial health effects. Pomegranates also act as a preventative measure for a variety of ailments, as per the promising results from ...
Irtiqa Shabir +10 more
doaj +2 more sources
Antifungal potential of punicalagin against Cryptococcus neoformans species complex [PDF]
Revista do Instituto de Medicina Tropical de São Paulo, 2018 This study evaluated the antifungal activity and cytotoxicity profile of the ellagitannin punicalagin, a compound extracted from the L. pacari A. St.-Hil (Lythraceae) leaf, against Cryptococcus neoformans species complex.
Thaísa Cristina Silva +9 more
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