Results 31 to 40 of about 2,738 (165)

Punicalagin attenuated allergic airway inflammation via regulating IL4/IL-4Rα/STAT6 and Notch- GATA3 pathways

open access: yesActa Pharmaceutica, 2022
Allergic asthma is an inflammatory disease of the airways which has a complex etiology. Punicalagin, a major polyphenol present in pomegranates, is reported to possess various biological properties including antioxidant and antiproliferative effects. The
Yu Li, Li Jianying
doaj   +1 more source

Punicalagin attenuates ventricular remodeling after acute myocardial infarction via regulating the NLRP3/caspase-1 pathway

open access: yesPharmaceutical Biology, 2023
Context Punicalagin has myocardial protection; the mechanism of punicalagin on ventricular remodeling (VR) after acute myocardial infarction (AMI) remains unclear.Objective These studies explore the role and mechanism of punicalagin in preventing and ...
Jian-fei Peng   +9 more
doaj   +1 more source

A Comparative Analysis of Punicalagin Interaction with PDIA1 and PDIA3 by Biochemical and Computational Approaches

open access: yesBiomedicines, 2021
In a previous work, it was shown that punicalagin, an active ingredient of pomegranate, is able to bind to PDIA3 and inhibit its disulfide reductase activity.
Giuliano Paglia   +7 more
doaj   +1 more source

Pharmacological Activities of Punicalagin: A Review

open access: yesJournal of Drug Delivery and Therapeutics, 2022
Traditional medicine was becoming more popular as a component of complementary and alternative medicine around the world. The ability to provide information on the pharmacological effects of plants requires a thorough understanding of the chemical components found in plants.
Fitra Fauziah, Sri Oktavia, Novia Rozadi
openaire   +1 more source

Differential Correlation of Transcriptome Data Reveals Gene Pairs and Pathways Involved in Treatment of Citrobacter rodentium Infection with Bioactive Punicalagin

open access: yesMolecules, 2023
This study is part of the work investigating bioactive fruit enzymes as sustainable alternatives to parasite anthelmintics that can help reverse the trend of lost efficacy. The study looked to define biological and molecular interactions that demonstrate
Damarius S. Fleming   +2 more
doaj   +1 more source

Punicalagin Damages the Membrane of Salmonella Typhimurium

open access: yesJournal of Food Protection, 2020
Salmonella, a bacterial foodborne pathogen, can contaminate meat, milk, and vegetables. While appropriate measures are available to control Salmonella, the inhibitory phytochemicals from plants are gaining increased attention. Punicalagin, a natural antimicrobial, is one of the main active tannins isolated from Punica granatum L.
Guanghui Li   +3 more
openaire   +2 more sources

Quantification of punicalagin in pomegranate peels from high-performance thin-layer chromatography

open access: yesBiomedical and Biotechnology Research Journal, 2022
Background: Punicalagin is the main phenolic compound present in pomegranate (Punica granatum), it possesses various kinds of activities which is very essential as a dietary supplement, herbal supplements, or nutraceuticals are widely available in the ...
Pooja Gadkari, Sanjay J Daharwal
doaj   +1 more source

Inhibitory Effect of Punicalagin on Inflammatory and Angiogenic Activation of Human Umbilical Vein Endothelial Cells

open access: yesFrontiers in Pharmacology, 2021
Punicalagin, a major ellagitannin isolated from pomegranate, is proved to have various pharmacological activities with an undefined therapy mechanism. The objective of this research was to demonstrate the effect of punicalagin on anti-inflammatory and ...
Wei Liu   +8 more
doaj   +1 more source

Punicalagin Ameliorates Lupus Nephritis via Inhibition of PAR2 [PDF]

open access: yesInternational Journal of Molecular Sciences, 2020
Lupus nephritis (LN) is the most frequent phenotype in patients with systemic lupus erythematosus (SLE) and has a high rate of progression to end-stage renal disease, in spite of intensive treatment and maintenance therapies. Recent evidence suggests that protease-activated receptor-2 (PAR2) is a therapeutic target for glomerulonephritis. In this study,
Yohan Seo   +10 more
openaire   +3 more sources

Punicalagin effect on total sleep deprivation memory deficit in male Wistar rats [PDF]

open access: yesJournal of Integrative Neuroscience, 2021
Sleep deprivation has deteriorating effects on cognitive functions and activation of brain inflammation mechanisms has been reported by some studies following total sleep deprivation.
Mohammad Nasehi   +3 more
doaj   +1 more source

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