Results 151 to 160 of about 3,384 (184)
Punicalagin inhibits neuroinflammation in LPS‐activated rat primary microglia
Molecular Nutrition and Food Research, 2014 ScopeIn this study, the effects of punicalagin on neuroinflammation in LPS‐activated microglia were investigated.Methods and resultsThe ability of punicalagin to reduce the production of TNF‐α, IL‐6 and prostaglandin E2 was measured in culture medium using enzyme immunoassay.
Olumayokun A Olajide +2 more
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Punicalagin promotes human villous trophoblast differentiation
Placenta, 2016 Poor differentiation of trophoblasts is associated with placental dysfunction, predisposing women to multiple pregnancy disorders. Punicalagin, a prominent ellagitannin in pomegranate juice has been shown to exert anti-apoptosis and anti-oxidative effects in human trophoblasts. We hypothesized that punicalagin modulates trophoblast differentiation.
Baosheng, Chen +3 more
openaire +3 more sources
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One-Step Purification of Punicalagin by Preparative HPLC and Stability Study on Punicalagin
Separation Science and Technology, 2010A novel, rapid, and high efficiency method to purify natural punicalagin by preparative HPLC is described. The optimum purification condition for punicalagin purification was 14% methanol in 0.1% trifluoroacetic acid solution as the mobile phase. The flow rate was 12 ml/min.
Ke Ding, Qipeng Yuan
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Punicalagin alleviates hepatotoxicity in rats challenged with cyclophosphamide
Environmental Toxicology and Pharmacology, 2016This study investigated the possible hepatoprotection of punicalagin in rats received cyclophosphamide (20mg/kg/day, i.p., for 7 days). Punicalagin given at two doses, 15 and 30mg/kg/day, p.o., for 7 days, starting the same day of cyclophosphamide administration.
Amr A Fouad, Hatem O Qutub
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In Vitro Studies on the Binding, Antioxidant, and Cytotoxic Actions of Punicalagin
Journal of Agricultural and Food Chemistry, 2007 The protective bioactivity of punicalagin, a high molecular weight polyphenol isolated from pomegranate fruit pith and carpellary membrane, against oxidative damages to lipids, amino acids constituting the proteins, and guanosine as a model for DNA has been investigated.
Anand P, Kulkarni +3 more
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Multifaceted Neuroprotective Role of Punicalagin: A Review
Neurochemical Research, 2023Millions of people worldwide are currently afflicted with neurologic conditions like a seizure, depression, stress, Alzheimer's disease, Parkinson's disease, and Huntington's disease. However, the precise etiopathology of these diseases is still unknown. Substantial studies are being conducted to discover more treatments against these disorders because
Nazia, Siddiqui +5 more
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Apoptotic Effects of Punicalagin on Partially Hepatectomized Rat Liver
, 2020 WOS: 000560030100016The antioxidant potential of pomegranate is attributed to its polyphenols, including punicalagin. In this study, we searched the effects of punicalagin on 70% partially hepatectomized rats.
Öge Artagan +2 more
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Punicalagin is a neuraminidase inhibitor of influenza viruses
Journal of Medical Virology, 2020AbstractInfluenza A virus (IAV) causes great morbidity and mortality worldwide every year. However, there are only a limited number of drugs clinically available against IAV infection. Further, emergence of drug‐resistant strains can render those drugs ineffective. Thus there is an unmet medical need to develop new anti‐influenza agents. In this study,
Ping, Li +11 more
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Nutrients, 2019 Punicalagin, a hydrolysable tannin of pomegranate juice, exhibits multiple biological effects, including inhibiting production of pro-inflammatory cytokines in macrophages.
Jihua Chen, Guofeng Ren, Lina Yang
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