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European Journal of Nutrition, 2003 11 pages, 10 figures, 1 table.[Background and Aims]: Punicalagin is an antioxidant ellagitannin of pomegranate juice. This compound is responsible for the high antioxidant activity of this juice.
Rafael Llorach +2 more
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Effects of Punicalagin and Punicalin on Carrageenan-Induced Inflammation in Rats
The American Journal of Chinese Medicine, 1999Punicalagin and punicalin were isolated from the leaves of Terminalia catappa L. In this study, we evaluated the anti-inflammatory activity of punicalagin and punicalin carrageenan-induced hind paw edema in rats. After evaluation of the anti-inflammatory effects, the edema rates were increased by carrageenan administration and reduced by drug ...
C C, Lin, Y F, Hsu, T C, Lin
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Gastroprotective activity of punicalagin and Lafoensia pacari in mice
Revista Brasileira de Farmacognosia, 2020Lafoensia pacari A. St.-Hil., Lythraceae, is used in Brazilian folk medicine to treat ulcer and gastritis; thus, it is important to conduct research so as to better understand its medicinal properties. The aim of this study was to assess the antisecretory and antiulcerogenic activities of lyophilized aqueous fraction and punicalagin isolated from ...
Beatriz A. Chaibub +5 more
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ChemInform Abstract: On the Structure of Punicalagin and Punicalin.
Chemischer Informationsdienst, 1986AbstractThe tanning agents punicalagin (I) and punicalin (II) both form an equilibrium mixture of α,β‐anomers.
G. SCHILLING, H. SCHICK
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Zur Struktur des Punicalagins und Punicalins
Liebigs Annalen der Chemie, 1985AbstractDie Gerbstoffe Punicalagin (1) und Punicalin (2) bilden in Lösung ein α,β‐Anomerengemisch. Die spektroskopischen Daten zeigen, daß diese Moleküle als natürliche Ansa‐Verbindungen angesehen werden können. Unter den Bedingungen der Glycosylierung weicht das System bei 2 in Richtung größerer Beweglichkeit des Makrocyclus aus: Entweder durch ...
Gerhard Schilling, Hartmut Schick
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Development of in situ forming implants for controlled delivery of punicalagin
International Journal of PharmaceuticsDue to efficient drainage of the joint, the development of intra-articular depots for long-lasting drug release is a difficult challenge. Moreover, a disease-modifying osteoarthritis drug (DMOAD) that can effectively manage osteoarthritis has yet to be identified.
Steven H. Elder +5 more
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Characterisation of Pomegranate‐Husk Polyphenols and Semi‐Preparative Fractionation of Punicalagin
Phytochemical Analysis, 2017AbstractIntroductionPomegranate‐husk is the main by‐product generated from the pomegranate industry. It is a potential source of compounds highly appreciated by different costumers. Punicalagin is the main compound present in pomegranate‐husk.ObjectiveTo characterise the pomegranate‐husk total polyphenols by HPLC‐ESI‐MS and to establish a method for ...
Pedro Aguilar‐Zárate +8 more
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Immune-suppressive activity of punicalagin via inhibition of NFAT activation
Biochemical and Biophysical Research Communications, 2008Since T cell activation is central to the development of autoimmune diseases, we screened a natural product library comprising 1400 samples of medicinal herbal extracts, to identify compounds that suppress T cell activity. Punicalagin (PCG) isolated from the fruit of Punica granatum was identified as a potent immune suppressant, based on its inhibitory
Sang-Ik, Lee +5 more
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Nephroprotection of punicalagin in rat model of endotoxemic acute kidney injury
Toxicology Mechanisms and Methods, 2016The potential nephroprotection of punicalagin (PNG) against lipopolysaccharide (LPS)-induced acute kidney injury in rats was investigated. Rats received a single i.v. dose of LPS (5 mg/kg), and treated with PNG (50 mg/kg, i.p.), 1 h before, and 1 h following LPS administration.
Amr A, Fouad +2 more
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Punicalagin as an Artemis inhibitor synergizes with photodynamic therapy in tumor suppression
Bioorganic ChemistryPhotodynamic therapy (PDT) is a minimally invasive treatment that utilizes a photosensitizer, specific light wavelengths, and oxygen to generate reactive oxygen species (ROS), causing oxidative damage and tumor cell death. However, the effectiveness of PDT can be reduced by the intrinsic antioxidant and DNA repair mechanisms of tumor cells.
Xuening, Chen +4 more
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