Results 91 to 100 of about 3,677 (187)

Punicalagin Protects Diabetic Nephropathy by Inhibiting Pyroptosis Based on TXNIP/NLRP3 Pathway

open access: yes, 2020
Diabetic nephropathy is a diabetic complication caused by chronic inflammation. As the primary polyphenol in pomegranate, punicalagin is believed to have significant anti-inflammatory properties.
Jihua Chen   +5 more
core   +1 more source

Punicalagin Protects Ram Sperm from Oxidative Stress by Enhancing Antioxidant Capacity and Mitochondrial Potential during Liquid Storage at 4 °C

open access: yesAnimals
The aim of this study was to investigate the effect of punicalagin, an antioxidant, on ram sperm quality. Semen samples were collected and pooled from five rams, then diluted using a Tris-based diluent containing various concentrations (0, 5, 15, 30 and ...
Liuming Zhang   +7 more
doaj   +1 more source

Differential correlation of transcriptome data to treat Citrobacter rodentium infection with punicalagin

open access: yes, 2023
This study is part of the work investigating bioactive fruit enzymes as sustainable alternatives to parasite anthelmintics that can help reverse the trend of lost efficacy. The study looked to define biological and molecular interactions that demonstrate
USDA-ARS-APDL (17912864)
core  

Pomegranate Peel Extract Microemulsions for Skin Delivery: Insights into Drug Release, Skin Permeation and UV Protection

open access: yesCosmetics
Pomegranate peel, an abundant agro-industrial by-product, represents a sustainable source of bioactive polyphenols, particularly punicalagin, which has been associated with antioxidant and photoprotective potential.
Nataša Bubić Pajić   +6 more
doaj   +1 more source

Impact of Punicalagin on the Physicochemical and Structural Properties of Wheat Flour Dough

open access: yesFoods, 2019
The study explored punicalagin (PGN) as a wheat flour enhancer. The impact of PGN on the physicochemical and structural properties of wheat flour have been investigated. It turned out that PGN increased the formation time, stability, tensile resistance, extension, and viscoelasticity of the dough at the concentrations of 0.13 and 0.26 mg/g.
Peng, Hong, Li, Bin, Tian, Jing
openaire   +3 more sources

Dual hypopigmentary effects of punicalagin via the ERK and Akt pathways

open access: yesBiomedicine & Pharmacotherapy, 2017
Punicalagin is a phenolic compound with antioxidant properties. However, the effects of punicalagin on melanin synthesis have been poorly evaluated. Therefore, we investigated the effects of punicalagin on melanogenesis in Mel-Ab cells. Punicalagin significantly inhibited melanin synthesis in a dose-dependent manner.
Jun Seob Shin   +7 more
openaire   +2 more sources

Punicalagin Attenuates Palmitate‐Induced Lipid Droplet Content by Simultaneously Improving Autophagy in Hepatocytes

open access: yes, 2020
SCOPE: Several studies show that excessive lipid intake can cause hepatic steatosis. To investigate lipotoxicity on cellular level, palmitate (PA) is often used to highly increase lipid droplets (LDs).
Tobias Jung   +9 more
core   +1 more source

Cognition enhancement of Punicalagin following intracerebroventricular injection of Aβ (25-35) model of mice: Cognition enhancement of Punicalagin

open access: yesInternational Journal of Biomedical and Advance Research, 2018
The hallmark in the pathology of Alzheimer disease is the deposition of amyloid plaques throughout the brain which lead to the deterioration of neuronal function and eventually they die. This damage spreads to hippocampus, region responsible for forming memories. This will ultimately lead to impairment in cognition.
Ittiyavirah, Sibi P, Raju, Rakhi
openaire   +1 more source

Computational investigations of potential inhibitors of monkeypox virus envelope protein E8 through molecular docking and molecular dynamics simulations

open access: yesScientific Reports
The World Health Organization (WHO) has declared the monkeypox outbreak a public health emergency, as there is no specific therapeutics for monkeypox virus (MPXV) disease. This study focused on docking various commercial drugs and plant-derived compounds
Rohit Das   +3 more
doaj   +1 more source

The Role of Punicalagin in Slowing Down the Decaying of Neurons

open access: yesMalaysian Journal of Medical and Biological Research, 2017
Punicalagin is an active compound found in the Pomegranate rind. The hallmark of the compound is its antioxidant properties which is more than most other sources such as Red wine. The poly-phenol donates hydrogen to free radicals like peroxynitrites and prevents it from oxidizing and destroying microglial cells in the brain.
openaire   +1 more source

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