Punicalagin Regulates Signaling Pathways in Inflammation-Associated Chronic Diseases [PDF]
Antioxidants, 2021 Inflammation is a complex biological defense system associated with a series of chronic diseases such as cancer, arthritis, diabetes, cardiovascular and neurodegenerative diseases.
Jie Xu +5 more
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Pharmacological Activities of Punicalagin: A Review [PDF]
Journal of Drug Delivery and Therapeutics, 2022 Traditional medicine was becoming more popular as a component of complementary and alternative medicine around the world. The ability to provide information on the pharmacological effects of plants requires a thorough understanding of the chemical components found in plants.
Fitra Fauziah, Sri Oktavia, Novia Rozadi
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Disruption of the nucleocapsid-RNA condensation by punicalagin is a broad-spectrum antiviral approach [PDF]
Fundamental ResearchThe formation of liquid condensates by nucleocapsid (N) protein and viral RNA is a critical and highly conserved event in the life cycle of numerous viruses. Targeting this process emerges as a possible strategy to combat viral infections.
Shao-Zhen Jiang +26 more
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A Comparative Analysis of Punicalagin Interaction with PDIA1 and PDIA3 by Biochemical and Computational Approaches [PDF]
Biomedicines, 2021 In a previous work, it was shown that punicalagin, an active ingredient of pomegranate, is able to bind to PDIA3 and inhibit its disulfide reductase activity.
Giuliano Paglia +7 more
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Pharmaceutical Biology, 2023 Context Punicalagin has myocardial protection; the mechanism of punicalagin on ventricular remodeling (VR) after acute myocardial infarction (AMI) remains unclear.Objective These studies explore the role and mechanism of punicalagin in preventing and ...
Jian-fei Peng +9 more
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Effect of punicalagin on proliferation of porcine ovarian granulosa cells in vitro [PDF]
Journal of Central European Agriculture, 2016 Punicalagin is a major component responsible for pomegranate's (Punica granatum) antioxidant properties. Punicalagin is the predominant ellagitannin of Punica granatum and present in two isomeric forms: punicalagin α and β.
Dagmara Packová, Adriana Kolesárová
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Punicalagin attenuated allergic airway inflammation via regulating IL4/IL-4Rα/STAT6 and Notch- GATA3 pathways [PDF]
Acta Pharmaceutica, 2022 Allergic asthma is an inflammatory disease of the airways which has a complex etiology. Punicalagin, a major polyphenol present in pomegranates, is reported to possess various biological properties including antioxidant and antiproliferative effects. The
Yu Li, Li Jianying
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Antibiofilm effects of punicalagin against Staphylococcus aureus in vitro
Frontiers in Microbiology, 2023 Staphylococcus aureus is a common foodborne pathogen which can form biofilms to help them resist to antimicrobials. It brings great harm to human health. Punicalagin has good antimicrobial activities against S. aureus, but its effect on biofilm formation
Yunfeng Xu +7 more
doaj +3 more sources
Punicalagin, a pomegranate compound, induces apoptosis and autophagy in acute leukemia [PDF]
PeerJ, 2021 Background Punicalagin is the major phenolic compound found in pomegranate peels. It has several reported medical benefits, including antioxidant, anti-inflammatory, and anticancer properties.
Paweena Subkorn +3 more
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Punicalagin promotes human villous trophoblast differentiation
Placenta, 2016 Poor differentiation of trophoblasts is associated with placental dysfunction, predisposing women to multiple pregnancy disorders. Punicalagin, a prominent ellagitannin in pomegranate juice has been shown to exert anti-apoptosis and anti-oxidative effects in human trophoblasts. We hypothesized that punicalagin modulates trophoblast differentiation.
Baosheng, Chen +3 more
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