Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Consumers' purchase decision in the context of western imported food products: Empirical evidence from Pakistan. [PDF]
Heliyon, 2023 Bukhari F +7 more
europepmc +1 more source
Analisis Pengaruh Harga, Promosi Dan Kualitas Produk Terhadap Keputusan Pembelian Batik Danar Hadi Surakarta [PDF]
, 2016 This research was conducted in Danar Hadi Batik Surakarta, which aims to analyze the effect of the Purchase Price to the Decision, to analyze the effect of promotion to the purchase decision.
, Dr. Edi Purwo Saputro, S.E., M.Si. +1 more
core
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Retracted: Impact of Factors of Online Deceptive Reviews on Customer Purchase Decision Based on Machine Learning. [PDF]
J Healthc Eng, 2023 Healthcare Engineering JO.
europepmc +1 more source
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Research on the Influence Path of Online Consumers' Purchase Decision Based on Commitment and Trust Theory. [PDF]
Front Psychol, 2022 You Y, Hu Y, Yang W, Cao S.
europepmc +1 more source
BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
FEBS Open Bio, EarlyView.The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
Pengaruh Harga dan Promosi Grab terhadap Brand Image yang Mempengaruhi Keputusan Pembelian Konsumen Pengguna Transportasi Berbasis Online [PDF]
, 2017 This research aims to understand the influence of the price set and promotional activities of Grab towards consumer purchase decision of through brand image as intervening variables. This research is a quantitative research. A number of samples taken are
Herwin, H. (Herwin) +1 more
core
Normative Consideration on Purchase Decision
Golden Ratio of Mapping Idea and Literature Format, 2021 The theory of planned behavior is a development of the theory of reasoned action (Ajzen, 1991). Basically the individual behavior of every human being is influenced by individual intentions (behavior intention). Behavioral intentions are influenced by three components, namely attitude, subjective norm, and perceived behavior control (Madden et al ...
openaire +1 more source