Results 71 to 80 of about 72,484 (264)

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

PENGARUH IKLAN TELEVISI DAN HARGA TERHADAP KEPUTUSAN PEMBELIAN SABUN LUX (SURVEI PADA PENGUNJUNG MEGA BEKASI HYPERMALL)

open access: yesJurnal Riset Manajemen Sains Indonesia, 2012
Generally, the purpose of this research are: 1) To determine the analytical description of the television advertisement, price and purchase decision of Lux soap (Survey on visitors of Mega Bekasi Hypermall), 2) To determine the effect of television ...
Setyo Ferry Wibowo, Maya Puspita Karimah
doaj  

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

ANALISIS PERILAKU KONSUMEN DALAM KEPUTUSAN PEMBELIAN SEPEDA MOTOR PADA MAHASISWA SE-MALANG RAYA

open access: yesJurnal Ekonomi Modernisasi, 2010
The development of motor vehicle industries especially motorcycle industries is an interesting phenomenon. Since the economic of Indonesia was declined, motorcyle industries indicated the improvment of sales.
Asna Asna
doaj   +1 more source

Consumers' purchase decision in the context of western imported food products: Empirical evidence from Pakistan. [PDF]

open access: yesHeliyon, 2023
Bukhari F   +7 more
europepmc   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

Can Augmented Reality Influence Consumer Responses? An Experiential Hierarchy Model Perspective

open access: yesJurnal Manajemen Teori dan Terapan
Objective: This study aims to examine how the key characteristics of Augmented Reality (AR) affect consumers’ psychological responses and purchase intention.
Deandra Vidyanata   +2 more
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

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