Results 41 to 50 of about 12,946,947 (287)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Decision-Making Within Technical Due Diligence for Land Development Using Machine Learning Algorithms

Applied Sciences
In the decision-making process related to the purchase of land properties intended for construction investments, the Technical Due Diligence (TDD) process plays a key role.
Elżbieta Radziszewska-Zielina, Marcin Waga, Bartłomiej Sroka   +2 more
doaj   +1 more source

The Industrial Purchasing Decision as a Political Process

European Journal of Marketing, 1975
Reports on an empirical study of the decision to purchase computers in a single firm. States it is a competitive bidding situation with several suppliers attempting to win a contract that eventually reached £3.5 million pounds. Illustrates how the politics of the firm can influence significant purchase decisions and, in particular, how gatekeepers ...
openaire   +2 more sources

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

The role of the brand in identifying patterns of the consumer decision-making process on the example purchasing a passenger car

Journal of Modern Science, 2023
Objectives Nowadays, the five-stage consumer decision-making process ends with the purchase of a specific brand of product. When searching for information, decision makers usually have specific categories that they search when solving a given decision ...
Paulina Agnieszka Jusiuk
doaj   +1 more source

Analysis of the consumer decision making process in purchasing rice

IOP Conference Series: Earth and Environmental Science, 2021
Abstract Rice is a food commodity that is consumed by many Indonesian people. With the presence of branded and unbranded rice in the sale of rice on the market, a study of consumer behavior needs to be done so that the consumer’s needs for rice products are in line with expectations.
A Amrullah, null Saadah, null Ferawati, A A Mandini, I Abubakar, S Y C Arfah, null Sulaeman   +6 more
openaire   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Influence of brand differential on motivation to conform and manufacturer versus store brand purchase intention [PDF]

International Journal of Business Science and Applied Management, 2014
Relationships and characteristics that influence consumers’ purchase decision between store brand and manufacturer brand product offerings have emerged as an interesting and practical area of research.
Tran, E., Balas, A. , Shao, C., Dubinsky, A., Jackson, L.   +4 more
doaj