Results 61 to 70 of about 865,036 (193)

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Prediction of pure loss of stability in following waves incorporating the effect of hydrodynamic lift force

Zhongguo Jianchuan Yanjiu
ObjectiveWhen ships sail in following waves, they often encounter complex nonlinear phenomena. Specifically, variations in waterplane area may lead to a significant reduction in the roll restoring force, and excessive surge forces on the ship can induce ...
Jinya ZHANG, Ning MA, Jianwen DUAN, Qiqi SHI   +3 more
doaj   +1 more source

Preparation and Characterization of MWCNTs/PVDF Conductive Membrane with Cross-Linked Polymer PVA and Study on Its Anti-Fouling Performance

Membranes, 2021
Based on carboxylated multi-walled carbon nanotubes (MWCNTs-COOH), a MWCNTs/PVDF conductive membrane was prepared by a vacuum filtration cross-linking method.
Yi Ding, Zhansheng Guo, Xinan Dong, Hong You, Junxue Mei, Xuguang Hou, Zhenlin Liang, Zhipeng Li   +7 more
doaj   +1 more source

Collagen-hyaluronic acid scaffolds for adipose tissue engineering. [PDF]

, 2010
Three-dimensional (3-D) in vitro models of the mammary gland require a scaffold matrix that supports the development of adipose stroma within a robust freely permeable matrix. 3-D porous collagen-hyaluronic acid (HA: 7.5% and 15%) scaffolds were produced
Cameron, RE, Campbell, JJ, Davidenko, N, Thian, ES, Watson, CJ   +4 more
core   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

State-of-the-art and prospects of direct stability assessment methods for second-generation intact stability criteria

Zhongguo Jianchuan Yanjiu
Intact stability of ships in waves is a fundamental guarantee for navigation safety. The direct stability assessment methods associated with the Second Generation Intact Stability Criteria (SGISC) remain undeveloped and have become a key focus of current
Min GU, Jilong CHU, Peijie ZHANG, Shuxia BU   +3 more
doaj   +1 more source

Preparation of Composite Insulating Paper With Decreased Permittivity, Good Mechanical and Thermal Properties by Kevlar/Nano Cellulose Fibrils/Softwood Pulp Hybrid

IEEE Access, 2019
Kevlar pulp treated with low-temperature plasma and nano cellulose fibrils (NCFs) have been introduced as reinforcements in the preparation for composite insulating paper with low relative permittivity, dielectric loss, good mechanical properties, and ...
Yang Mo, Lijun Yang, Tiantian Zou, Wei Hou, Ruijin Liao   +4 more
doaj   +1 more source

Co-Crystallization Approach to Enhance the Stability of Moisture-Sensitive Drugs

Pharmaceutics, 2023
Stability is an essential quality attribute of any pharmaceutical formulation. Poor stability can change the color and physical appearance of a drug, directly impacting the patient’s perception.
Madhukiran R. Dhondale, Pradip Thakor, Amritha G. Nambiar, Maan Singh, Ashish K. Agrawal, Nalini R. Shastri, Dinesh Kumar   +6 more
doaj   +1 more source

Polyetherimide foams filled with low content of graphene nanoplatelets prepared by scCO2 dissolution [PDF]

, 2019
Polyetherimide (PEI) foams with graphene nanoplatelets (GnP) were prepared by supercritical carbon dioxide (scCO2) dissolution. Foam precursors were prepared by melt-mixing PEI with variable amounts of ultrasonicated GnP (0.1–2.0 wt %) and foamed by one ...
Abbasi, Hooman, Antunes, Marcelo de Sousa Pais, Velasco Perero, José Ignacio   +2 more
core   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source